Cdh17 Positive Advanced Solid Tumors

2

Review clinical trials related to Cdh17 Positive Advanced Solid Tumors. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma

This study is looking at how safe BHB810 is in adults with gastric and gastroesophageal adenocarcinoma (GEJ). The purpose of this study is also to look at: how well the study drug works, how the study drug moves into, through, and out of the body, and how your body reacts to the study drug. Participants will get an IV infusion of BHB810 every 2 weeks while on study treatment.

Participants needed: 164
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: BigHat Biosciences, Inc.Updated: May 8, 2026
Eligibility criteria

Participant must be ≥ 18 years or the legal age of consent in the jurisdiction i... [+6]

Chemotherapy or targeted therapy withing 4 weeks or 5-halflives (whichever is sh... [+11]

Status: Recruiting

Safety and Preliminary Efficacy of Anti-CDH17 CAR-T Cell Therapy in Patients with CDH17-positive Advanced Solid Tumors

This is a single-center, open-label, single-arm study to evaluate the safety and preliminary efficacy of anti-CDH17 CAR-T cells in patients with CDH17-positive advanced solid tumors.

Participants needed: 30
Trial details
Phase: Early Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: 920th Hospital of Joint Logistics Support Force of People's Liberation Army of ChinaUpdated: Feb 11, 2025Locations: 1
Eligibility criteria

The patient understands and voluntarily signs the informed consent form, and is... [+7]

Patients with prior or current other malignancies; [+14]