[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cervical-myelopathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cervical-myelopathy":239},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,53,80,104,127,150,172,193,220],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100451833",false,"NCT05163639","Spinal Cord Associative Plasticity Study","SCAP","NON-INVASIVE\n\nInclusion Criteria:\n\n(All participants)\n\n* Age between 18-80 years.\n* Must have stable prescription medication for 30 days prior to screening\n* Must be able to: abstain from alcohol, smoking and caffeine consumption on the day of each experiment; abstain from recreational drugs for the entirety of the study; commit to study requirements (i.e., 7 visits); provide informed consent.\n\n(Able-bodied participants)\n\n* No known central or peripheral neurological disease or injury.\n\n(SCI participants - including patients scheduled for intraoperative procedures)\n\n* Score of 1-4 (out of 5) on manual muscle testing of finger extension, finger flexion, or finger abduction in left or right hand.\n\nExclusion criteria:\n\n(All participants)\n\n* Personal or extensive family history of seizures;\n* Ventilator dependence or patent tracheostomy site;\n* Use of medications that significantly lower seizure threshold, such as amphetamines, neuroleptics, dalfampridine, and bupropion;\n* History of stroke, brain tumor, brain abscess, or multiple sclerosis;\n* History of moderate or severe head trauma (loss of consciousness for greater than one hour or evidence of brain contusion or hemorrhage or depressed skull fracture on prior imaging);\n* History of implanted brain\u002Fspine\u002Fnerve stimulators, aneurysm clips, ferromagnetic metallic implants in the head (except for inside mouth); cochlear implants; cardiac pacemaker\u002Fdefibrillator; intracardiac lines; currently increased intracranial pressure; or other contraindications to brain or spine stimulation;\n* Significant coronary artery or cardiac conduction disease; recent history of myocardial infarction and heart failure with an ejection fraction of less than 30% or with a New York Heart Association Functional Classification of Class III or IV;\n* Recent history (within past 6 months) of recurrent autonomic dysreflexia, defined as a syndrome of sudden rise in systolic pressure greater than 20 mm Hg or diastolic pressure greater than 10 mm Hg, without rise in heart rate, accompanied by symptoms such as headache, facial flushing, sweating, nasal congestion, and blurry vision (this will be closely monitored during all screening and testing procedures);\n* History of significant hearing problems;\n* History of bipolar disorder;\n* History of suicide attempt;\n* Active psychosis;\n* Recent history (\\>1 year) of chemical substance dependency or significant psychosocial disturbance;\n* Heavy alcohol consumption (greater than equivalent of 5oz of liquor) within previous 48 hours;\n* Open skin lesions over the face, neck, shoulders, or arms;\n* Pregnancy; and\n* Unsuitable for study participation as determined by study physician.\n\nINTRA-OPERATIVE\n\nInclusion Criteria:\n\n* Clinical indication for cervical spine surgery.\n\nExclusion criteria:\n\n(For experiments involving cortical stimulation)\n\n* Epilepsy;\n* A history of skull surgery with metal implants;\n* Cochlear implants;\n* Patients with aneurysm stents in neck or brain blood vessels;\n* Evidence of skull shrapnel; (For experiments involving spinal cord stimulation)\n* Stimulation devices in the neck or chest (e.g., vagal nerve stimulation, cardiac patients with pacemakers)",true,"ALL","18 Years","80 Years",{"count":20,"type":21},92,"ESTIMATED","INTERVENTIONAL",[24],"EARLY_PHASE1","Spinal cord associative plasticity (SCAP) is a combined cortical and spinal electrical stimulation technique developed to induce recovery of arm and hand function in spinal cord injury.\n\nThe proposed study will advance understanding of SCAP, which is critical to its effective translation to human therapy. The purpose of the study is to:\n\n1. Determine whether signaling through the spinal cord to the muscles can be strengthened by electrical stimulation.\n2. Improve our understanding of the spinal cord and how it produces movement.\n3. Determine whether spinal surgery to relieve pressure on the spinal cord can improve its function.\n\nAim 1 is designed to advance mechanistic understanding of spinal cord associative plasticity (SCAP).\n\nAim 2 will determine whether SCAP increases spinal cord excitability after the period of repetitive pairing. In rats, SCAP augments muscle activation for hours after just 5 minutes of paired stimuli.\n\nWhereas Aims 1 and 2 focused on the effects of paired stimulation in the context of uninjured spinal cord, Aim 3 assesses whether paired stimulation can be effective across injured cord segments. Aim 3 will incorporate the experiments from Aim 1 and 2 but in people with SCI, either traumatic or pre-operative patients with myelopathy in non-invasive experiments, or targeting myelopathic segments in intraoperative segments.",[27,28,29],"Cervical Spinal Cord Injury","Tetraplegia\u002FTetraparesis","Cervical Myelopathy",[31,32,33,34,35,36,37,38,39],"spinal cord injury","paired brain and spinal cord stimulation","convergent stimulation","spinal cord associative plasticity","transcutaneous spinal cord stimulation","intraoperative monitoring","upper-limb muscle activation","motor cortex","cervical spinal cord","RECRUITING","2026-06-16",{"date":43,"type":44},"2026-06-18","ACTUAL",{"date":46,"type":44},"2021-09-10",{"date":48,"type":21},"2027-12-30",{"name":50,"class":51},"Columbia University","OTHER",3,{"id":54,"slug":4,"hasResults":10,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":63,"conditions":64,"keywords":65,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100643685","NCT07636135","Timing of Rehabilitation Following Cervical Spinal Surgery in Degenerative Myelopathy","Feasibility of Early Post-operative Rehabilitation Following Cervical Spinal Surgery in Degenerative Myelopathy","Inclusion Criteria:\n\n* adult (\\>18 years of age) with diagnosis of degenerative cervical myelopathy, within 2 weeks of spinal decompression surgery\n* plan to be discharged home from acute care (i.e., not admitted to another facility for post-operative rehabilitation)\n* able to stand with a maximum of one-person assist (+\u002F- use of gait aid)\n* persistent functional impairment in lower extremity strength, balance, coordination, and\u002For gait\n* ability to attend an 8-week in-person rehabilitation program in Edmonton, Alberta\n\nExclusion Criteria:\n\n* discharge from acute care facility \\> 2 weeks post-operative\n* intra-operative or early post-operative complication delaying discharge or precluding participation in early rehabilitation",{"count":60,"type":21},20,[62],"NA","The goal of this clinical trial is to learn whether starting rehabilitation earlier after surgery can improve recovery and is feasible and acceptable for adults with degenerative cervical myelopathy (DCM) undergoing cervical spine surgery. The main question it aims to answer is:\n\nDoes starting rehabilitation earlier improve walking, balance, physical activity, quality of life, and nervous system function after surgery?\n\nResearchers will compare participants who begin rehabilitation two weeks after surgery with participants who begin rehabilitation six weeks after surgery to see if earlier rehabilitation leads to better recovery outcomes and participation.\n\nParticipants will:\n\nBe randomly assigned to begin rehabilitation either two weeks or six weeks after surgery.\n\nAttend physical therapy sessions twice per week for eight weeks focused on strength, balance, and walking.\n\nComplete assessments of walking ability, balance, physical activity, quality of life, and nervous system function over several months after surgery.\n\nProvide feedback about their experience with the rehabilitation program, including satisfaction and any side effects or challenges related to participation.",[29],[66,67,68,69,31],"physical therapy","post-operative rehabilitation","walking","degenerative cervical myelopathy","NOT_YET_RECRUITING","2026-06-04",{"date":73,"type":44},"2026-06-09",{"date":75,"type":21},"2026-06-15",{"date":77,"type":21},"2027-12-31",{"name":79,"class":51},"University of Alberta",{"id":81,"slug":4,"hasResults":10,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":15,"sex":16,"minAge":86,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":89,"phases":4,"briefSummary":90,"conditions":91,"keywords":92,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":103},"100453394","NCT05183971","Proprioceptive Deficits in Degenerative Cervical Myelopathy","Early Detection of Proprioceptive Dysfunction in Degenerative Cervical Myelopathy by Proprioceptive Functional Analysis in Activities of Daily Living","Inclusion Criteria:\n\n* Chinese\n* Aged 50 or above\n* With radiological evidence of degenerative cervical myelopathy, both symptomatic and asymptomatic\n* Nurick grade less than 3\n\nExclusion Criteria:\n\n* Non-Chinese ethnicity\n* Aged under 50\n* without any radiological proof of cervical myelopathy\n* Active problems of tuberculosis spine, lumbar spinal diseases, and other problems causing pain or deformities over the limbs that may affect their balance and movement\n* Presents with extra-pyramidal or other disorders involving the cerebellum or frontal lobe of the cerebrum leading to poor balance and gait disturbance\n* Previous spinal operation with residual disturbance in balance or gait\n* Non-communicable patients with insufficient cognitive ability to express their symptoms clearly\n* Non-walker\n* Blind or deaf","50 Years",{"count":88,"type":21},100,"OBSERVATIONAL","Proprioceptive deficits in degenerative cervical myelopathy (DCM) is a progressive neurological deficits in somatosensory and motor function which affects the body balance and motor control. DCM usually presents with body incoordination, hand clumsiness and gait disturbance associated with proprioceptive dysfunction that hinders the physical performance and functions. In this study, a non-invasive assessment protocol on proprioception will be developed for detecting subtle proprioceptive deficits at the early stage of disease through simple Physical Performance Tests for population older than 45. By adopting the physical performance tests as the diagnostic predictors of DCM, we aim to avoid the development of devastating consequences and disabilities.",[29],[93,94],"Degenerative Cervical Myelopathy","Proprioceptive Deficits","2026-06-02",{"date":71,"type":44},{"date":98,"type":44},"2022-09-01",{"date":100,"type":21},"2046-09-30",{"name":102,"class":51},"The University of Hong Kong",1,{"id":105,"slug":4,"hasResults":10,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":10,"sex":16,"minAge":86,"maxAge":4,"enrollmentInfo":109,"targetDuration":4,"studyType":22,"phases":111,"briefSummary":112,"conditions":113,"keywords":115,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":52},"100584749","NCT06893406","Cervical Myelopathy in Hip Fracture Patients","Inclusion Criteria:\n\n* Patient admitted to Eskenazi, Methodist, or IU North hospital for a hip fracture (femoral neck, intertrochanteric, subtrochanteric, or pertrochanteric fracture) that was caused by a ground level fall.\n\nExclusion Criteria:\n\n* Neurologic or cognitive disorder explaining the fall (dementia, Parkinson's disease, delirium, etc.)\n* Syncopal fall or fall caused by stroke or a heart condition",{"count":110,"type":21},75,[62],"Recent evidence has demonstrated a high rate of undiagnosed cervical myelopathy in patients presenting with hip fractures from a ground level fall. Identification and treatment of cervical myelopathy can help prevent falls and future fragility fractures. The purpose of this study is to screen ground level fall hip fracture patients for cervical myelopathy using a history, physical exam, and then offer an MRI if indicated.",[29,114],"Hip Fractures",[116,117],"Hip fracture","Cervical myelopathy","2026-05-26",{"date":120,"type":44},"2026-05-28",{"date":122,"type":44},"2025-05-01",{"date":124,"type":21},"2026-07-30",{"name":126,"class":51},"Indiana University",{"id":128,"slug":4,"hasResults":10,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":4,"eligibilityCriteria":132,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":133,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":135,"conditions":136,"keywords":139,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":4},"100583414","NCT06876012","Impact of Tai Chi in Cervical Myelopathy","Impact of Tai Chi on Balance and Fall Risk in Patients With Cervical Myelopathy","Inclusion Criteria:\n\n* Diagnosis of Cervical Myelopathy with planned surgery\n* 18 years of age or older\n* Able to participate in intervention (attend and participate in classes)\n\nExclusion Criteria:\n\n* Wheelchair bound at initial visit\n* Other verified potential cause of gait instability\u002Fbalance problems\n* Unable to participate in intervention (unable to attend\u002Fparticipate in classes)",{"count":60,"type":21},[62],"The goal of this observational study is to determine if patients with cervical myelopathy who participate in a Tai Chi program will demonstrate improved gait and balance compared to patients who undergo usual care.\n\nParticipants must be 18 years or older and have a diagnosis of cervical myelopathy.",[29,137,138],"Balance Assessment","Fall Risk",[140],"Surgery","2026-04-10",{"date":143,"type":44},"2026-04-15",{"date":145,"type":21},"2026-12",{"date":147,"type":21},"2028-07",{"name":149,"class":51},"West Virginia University",{"id":151,"slug":4,"hasResults":10,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":155,"eligibilityCriteria":156,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":157,"enrollmentInfo":158,"targetDuration":160,"studyType":89,"phases":4,"briefSummary":161,"conditions":162,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":103},"100473543","NCT05446259","Degenerative Cervical Myelopathy Repository","Development of a Predictive Outcome Model for Patients With Degenerative Cervical Myelopathy Using Objective Functional and Biological Measures.","DCM","Inclusion Criteria:\n\n* Diagnosis of degenerative cervical myelopathy\n* Diagnosis of cervical degenerative disease without myelopathy\n\nExclusion Criteria:\n\n* None outside or diagnostic requirements and age limits.","100 Years",{"count":159,"type":21},245,"2 Years","To create a research repository of patients with known degenerative cervical myelopathy (DCM) and a control cohort of subjects who have non-myelopathic spinal disease. This repository will be used to assess functional and\u002For biological measures that may allow for improved prediction of symptomatic progression and response to treatment in patients with DCM. In addition, this repository will be used to develop a risk assessment scale to accurately predict functional outcomes following operative management of DCM.",[29],"2026-02-10",{"date":165,"type":44},"2026-02-13",{"date":167,"type":44},"2022-07-13",{"date":169,"type":21},"2028-05",{"name":171,"class":51},"Francis Farhadi",{"id":173,"slug":4,"hasResults":10,"nctId":174,"briefTitle":175,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":22,"phases":179,"briefSummary":180,"conditions":181,"keywords":182,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":192},"100569990","NCT06701422","Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery","Inclusion Criteria:\n\n•Clinical indication for cervical spine surgery.\n\nExclusion criteria:\n\n•Stimulation devices in the neck or chest (e.g., vagal nerve stimulation, cardiac patients with pacemakers)",{"count":178,"type":21},36,[62],"The proposed study seeks to understand how the cervical spinal cord should be stimulated after injury through short-term physiology experiments that will inform a preclinical efficacy trial. The purpose of this study is to determine which cervical levels epidural electrical stimulation (EES) should target to recruit arm and hand muscles effectively and selectively in spinal cord injury (SCI).",[27,28,29],[31,37,39,183],"myelopathy","2025-11-20",{"date":186,"type":44},"2025-11-24",{"date":188,"type":44},"2024-12-06",{"date":190,"type":21},"2026-06-30",{"name":50,"class":51},2,{"id":194,"slug":4,"hasResults":10,"nctId":195,"briefTitle":196,"officialTitle":196,"acronym":197,"eligibilityCriteria":198,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":199,"targetDuration":4,"studyType":22,"phases":201,"briefSummary":202,"conditions":203,"keywords":207,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":219,"locationsCount":103},"100556048","NCT06520020","Evaluating Safety and Feasibility of Transcutaneous Spinal Cord Stimulation Following Traumatic and Non-Traumatic Spinal Cord Injury: A Pilot Study","STIM","Inclusion Criteria:\n\n* Age: = 18 years and = 80 years.\n* Written informed consent by patient and\u002For legal authorized representative (LAR).\n* No other life-threatening condition.\n* No evidence of sepsis.\n* No evidence of superficial skin infection at site of surgery and intervention.\n* An established diagnosis of either:\n\n  * cervical myelopathy with modified Japanese Orthopaedic Association score of 8-14, or\n  * acute cervical \u002F thoracic SCI with ASIA Impairment Scale grade A-D (as assessed within 72 hours of injury) with neurologic level of injury (NLI) from C2 to T12.\n* The ability to undergo, or have had, surgical intervention. -. The ability to undergo transcutaneous intervention including study procedures in the posterior cervical or thoracic midline at or after 14 days from surgery.\n\nExclusion Criteria:\n\n* Any concomitant impairment of the upper and lower limb at baseline that could potentially confound the neurologic assessments; including but not limited to traumatic or disease conditions like brachial plexus injury, peripheral neuropathy, spinal hematoma, transverse myelitis, non-compressive myelopathy, dementia, and Parkinson's disease.\n* mJOA of \\>= 15 and \\\u003C= 7, or AIS grade E tSCI at baseline assessment.\n* Currently involved in another non-observational ntSCI or tSCI study, or receiving another interventional drug, that could interfere with recordings and confound adverse events.\n* Other illness (including mental disorder) that could preclude accurate medical and neurological evaluation, at discretion of the treating surgeon and\u002For principal investigator.\n* Unable to commit to the follow-up schedule.\n* Recent history of regular substance abuse (illicit drugs, alcohol), which in the opinion of the investigator would interfere with the subject's participation in the study.\n* Any condition likely to result in the patient's death within the next 12 months.\n* Prisoner.\n* Pregnancy.\n* Cardiac pacemaker dependent, unable to undergo electrical stimulation.\n* Brain implant, skull prosthesis, plate and screws limiting transcranial stimulation.\n* Tattoo at site of skin electrode that causes heat\u002Fpain during stimulation.\n* Subjects who in the opinion of the investigator are not suitable for inclusion in the study, with reason documented.",{"count":200,"type":21},30,[62],"The study will be a non-randomized, non-blinded pilot study to analyze the safety and feasibility of a non-significant risk device, transcutaneous spinal cord stimulation. The aim is to include 30 total patients, 10 patients in each of 3 groups:\n\n1. Non-traumatic spinal cord injury (ntSCI) with diagnosis of degenerative cervical myelopathy and offered surgical intervention.\n2. Early tSCI screened during the hospital admission when cervical\u002Fthoracic spinal injury was diagnosed.\n3. Delayed tSCI (control) screened 6-24 months after acute cervical\u002Fthoracic spinal injury.",[204,205,206,29],"Spinal Cord Stimulation","Electric Stimulation Therapy","Traumatic Spinal Cord Injury",[208,209,210,211,212],"Stimulation","Transcutaneous","MagStim","Transcranial","Magnetic","2025-06-05",{"date":215,"type":44},"2025-06-06",{"date":217,"type":44},"2024-10-23",{"date":190,"type":21},{"name":171,"class":51},{"id":221,"slug":4,"hasResults":10,"nctId":222,"briefTitle":223,"officialTitle":223,"acronym":224,"eligibilityCriteria":225,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":226,"targetDuration":4,"studyType":22,"phases":227,"briefSummary":228,"conditions":229,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":231,"startDateStruct":233,"completionDateStruct":235,"leadSponsor":237,"locationsCount":103},"100553434","NCT06486038","Quatitative MRI of the Spinal Cord in Cervical Myelopathy: Assessment of Microstuctural Damage for Outcome Improvement","QCEMY","Inclusion Criteria:\n\n1. Subjects willing and able to give informed consent for participation in the study.\n2. Age 18-80.\n3. Subjects under evaluation for potential surgical intervention of anterior cervical discectomy and fusion as established by a board-certified neurosurgeon based on clinical and radiological findings according to good clinical practice.\n4. Grade I-III single level sub-axial (C3-C7) cervical spinal canal stenosis (Kang, AJR 2011) on a preliminary anatomical MRI.\n5. Deficitary or irritative cervical spinal cord symptoms and\u002For signs in concordance with MRI findings.\n\nExclusion Criteria:\n\n1. Subjects unable o.r unwilling to give informed consent .\n2. Age \\\u003C18 or \\> 80\n3. Subjects with pacemaker or any other contraindication to undergo high-field (3 Tesla) MRI exam.\n4. Pregnancy or planned pregnancy before the end of the study .\n5. Co-existing or prior neurological disease of the brain, SC, or peripheral nervous system.\n6. Co-existing or prior oncologic disease .\n7. Prior surgery in the brain or spine.",{"count":88,"type":21},[62],"The aim of this low interventional study is to detect microstructural degeneration prior to the presentation, worsening, or persistence following surgical or conservative treatment of cervical degenerative myelopathy signs and symptoms using quantitative imaging metrics and functional biometric analysis.\n\nThe endpoints of the study are to collect and compare the clinical, biometric, neurophysiological and imaging data.\n\nThe objectives of the study are:\n\n* to implement and validate a novel quantitative Magnetic Resonance (qMRI) protocol clinically for the identification and quantification of microstructural spinal cord damage\n* to compare qMRI data to clinical and neuromotor's and corresponding neurophysiological data\n* to create an integrated diagnostic tool for early diagnosis and disease monitoring of myelopathy, and for identification of a more reproducible and quantitative scale for assessing reversible and irreversible spinal cord damage combining clinical, biometric, imaging and neurophysiological data in patients suitable for surgical or non-surgical treatment.\n\nPatient will undergo:\n\n* MRI (baseline - 1 month- 6 months)\n* clinical data collection (baseline- 1 month - 6 months)\n* neuromotor assessment (baseline - 1 month - 6 months)\n* neurophysiological assessment (baseline - 6 months)\n* surgery if applicable Quantitative MRI of the spinal cord could provide a new objective system for identification of patients who require surgery before developing irreversible clinical damage, and to avoid surgical treatment in those who do not require it. Additionally, quantitative MRI, in combination with clinical data such as, neuromotor tests, could provide an important approach to assess the effectiveness of the therapeutical approach.",[29],"2024-07-08",{"date":232,"type":44},"2024-07-10",{"date":234,"type":44},"2024-04-03",{"date":236,"type":21},"2025-05-31",{"name":238,"class":51},"Istituto Clinico Humanitas",""]