[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-disease":742},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,59,0,25,[9,47,74,113,143,169,195,223,250,276,306,356,386,415,453,487,516,548,572,600,622,648,667,692,711],{"id":10,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100573579",false,"NCT06748118","Improving Patients' Adherence to Their Chronic Treatments by Implementing a Simple, Standardized and Redundant Message Delivered by Healthcare Professionals.","Improving Patients' Adherence to Their Chronic Treatments by Implementing a Simple, Standardized and Redundant Message Delivered by Healthcare Professionals: a Stepped-wedge Multicenter Randomized Trial","MAPS","Inclusion Criteria:\n\n* Adult patients (age ≥ 18 years)\n* Affiliated to the French social security system\n* Followed in hospital for a chronic pathology within a formalized care pathway\n* Having signed a consent form to participate in the study.\n\nExclusion Criteria:\n\n* Patients included in the control period.\n* Patients under guardianship.\n* Pregnant or breast-feeding patients.\n* Patients taking part in research on compliance","ALL","18 Years",{"count":20,"type":21},1210,"ESTIMATED","INTERVENTIONAL",[24],"NA","The primary objective in this study is to achieve a 15% 6-month improvement in therapeutic adherence among patients with chronic pathologies, thanks to a simple, standardized and redundant message delivered by healthcare professionals during consultations\u002Finterviews Trained healthcare professionals deliver a simple, standardized and redundant 3-point message to patients, based on the levers of action concerning therapeutic adherence. This message is delivered with the aim of modifying the patient's behavior with regard to treatment intake.",[27,28,29,30],"Chronic Disease","Therapeutic Adherence","Training Group, Sensitivity","Delivery Simple, Standardized & Redundant Message to Patient",[32,33],"intervention study","stepped wedge study","RECRUITING","2026-06-29",{"date":37,"type":38},"2026-07-01","ACTUAL",{"date":40,"type":38},"2026-03-18",{"date":42,"type":21},"2028-03",{"name":44,"class":45},"Assistance Publique - Hôpitaux de Paris","OTHER",10,{"id":48,"slug":4,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100644131","NCT07666373","Burden of Care and Health Literacy of Caregivers in the Emergency Department","The Relationship Between Caregiver Burden and Health Literacy Among Caregivers of Patients With Chronic Diseases Presenting to the Emergency Department","The patient having visited the Yalova Training and Research Hospital Emergency Department.\n\nBeing at least 18 years of age. Being cognitively capable of answering the data collection tools (scales\u002Fquestionnaires).\n\nVolunteering to participate in the study and providing informed consent.\n\nExclusion Criteria:\n\nRefusal to participate in the research voluntarily. Not being the primary caregiver for the patient. Inability to communicate or complete the scales due to cognitive or language barriers.\n\n\\-",true,{"count":55,"type":21},350,"OBSERVATIONAL","This study aims to investigate the relationship between caregiver burden and health literacy among primary caregivers of patients with chronic diseases presenting to the emergency department. The study will be conducted in the Emergency Department of Yalova Training and Research Hospital and will include at least 300 caregivers. Data will be collected using a sociodemographic questionnaire, the Turkish Health Literacy Scale-32 (THLS-32), and the Zarit Burden Interview (ZBI). The findings are expected to contribute to a better understanding of caregivers' needs and to clarify the role of health literacy in caregiver burden among those providing care for individuals with chronic illnesses.",[59,60,27,61],"Caregiver Burden","Health Literacy","Emergency Service Utilization",[59,60,63,64],"Family Caregivers","Emergency Service","NOT_YET_RECRUITING","2026-06-18",{"date":68,"type":38},"2026-06-24",{"date":37,"type":21},{"date":71,"type":21},"2027-05-31",{"name":73,"class":45},"University of Yalova",{"id":75,"slug":4,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":22,"phases":82,"briefSummary":83,"conditions":84,"keywords":93,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":112},"100626901","NCT07441655","Families Implementing Good Health Traditions for Life","FIGHT for Life","Inclusion Criteria:\n\n1. Family 1.a.) Black Parent\u002FGuardian: age 18 years or older residing in the same household with child (i.e., biological or have legal guardianship for child) 1.b.) Child: age 8-15 years old\n2. Parent\u002FGuardian have HbA1c level 5.7-6.4% (prediabetes)\n3. Parent\u002FGuardian willing to commit to participation in a 20-month research study and have no plans to move from the area over the next 20-months\n4. Parent\u002Fchild are ambulatory and able to participate in physical activity\n\nExclusion Criteria:\n\n1. Individuals with severe psychological disorders that may prevent\u002Finterfere with study participation\n2. Physical impairments that may prevent participation in moderate intensity physical activity;\n3. Previous diagnosis of diabetes\n4. History of congestive heart failure, renal failure, or recent (\\\u003C12 months) cardiovascular events such as myocardial infarction or stroke;\n5. Person taking medications that may affect endpoint analyses\n6. Persons with co-morbid contraindications to physical activity or dietary changes.\n7. Currently pregnant or planning to become pregnant in the next year.",{"count":81,"type":21},70,[24],"This study will provide evidence for the utility of using a community-engaged research approach to implement a tailored, family-oriented adaptation of the Diabetes Prevention Program that will have positive effects on risk factors associated with type 2 diabetes morbidity and mortality among Black families in a Southwest Georgia community.",[85,27,86,87,88,89,90,91,92],"Diabetes","Type 2 Diabetes","Healthy Lifestyle","Nutrition, Healthy","Sedentary Behavior","Family","Family Research","Family and Household",[94,95,96,97,98,99,100,101,102,103],"diabetes","rural","type 2 diabetes","nutrition","physical activity","diabetes prevention","family research","family and household","chronic disease","sedentary behavior",{"date":105,"type":38},"2026-06-23",{"date":107,"type":38},"2026-02-04",{"date":109,"type":21},"2028-04-30",{"name":111,"class":45},"Morehouse School of Medicine",1,{"id":114,"slug":4,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":17,"minAge":119,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":22,"phases":122,"briefSummary":123,"conditions":124,"keywords":128,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":142},"100563444","NCT06616246","Training Community Members to be Coaches to Deliver the HealthyLifetime Program","Evaluating the Use of Community Members Trained as Health Coaches to Deliver the HealthyLifetimeTM Program","Inclusion Criteria:\n\n* Be at least 30 years of age, with no more than three, uncomplicated chronic conditions and want to learn to take better care of their health.\n* Independent Living Index (ILI) greater than 35. ILI is derived by averaging the outcome measures scores.\n* A score of less than 4 on items related to anxiety and depressive symptoms\n* Have Medicare and\u002For Medicaid insurance.\n* Be able to read, speak, and hear English - but may use glasses or hearing aids, if needed;\n* Tell us their age, date of birth, address, and phone number, and explain their health problems;\n* Have a computer, iPad (Tablet), or Smartphone with an Internet connection, email address, a working camera, and microphone;\n* Be able to use their computer\u002Ftablet to connect to video chat sessions like Zoom in a private space in their home or a private room\n* Are not currently participating in any other studies involving diet, weight management, exercise and\u002For coaching at the current time; and\n* Reside in Michigan.\n\nExclusion Criteria:\n\n* ● Are less than 30 years of age.\n\n  * Have more than three, uncomplicated chronic conditions.\n  * A score of more than 4 on items related to anxiety and depressive symptoms\n  * Do not have Medicare and\u002For Medicaid insurance.\n  * Do not reside in Michigan.\n  * Have a new acute health problem that requires seeing a doctor more than once a month for acute medical treatment.\n  * Have been told their illness is not curable.\n  * Need help remembering their name, date of birth, or health problems.\n  * Cannot use glasses or a hearing aid to see or hear well enough to read materials on the computer or talk to the nurse easily.\n  * Are currently participating in any other studies involving diet, weight management, exercise and\u002For coaching at the current time; and\n  * Do not have, or cannot use, a computer, iPad, or another device with the Internet at home to use Zoom (e.g., internet streaming).","30 Years",{"count":121,"type":21},300,[24],"The goal of this randomized controlled study is to learn if, in addition to nurses, community members can be trained as health coaches to deliver the HealthyLifetime (HL) program to people without complex chronic health conditions, an intervention that provides a short-term and effective health coaching intervention delivered through a virtual platform to improve health, resiliency, and independent self-care to participants who are without complex chronic conditions. The main question it aims to answer is:\n\n• Can Community Health Coaches achieve the same level of competency and outcome as Nurse Health Coaches in participants without complex chronic conditions?",[125,126,27,127],"Health Behaviors","Functional Decline","Risk Factors",[129,130,131,132,133],"health coach","health resiliency","independent self-care","community health workers","independent aging",{"date":135,"type":38},"2026-06-22",{"date":137,"type":38},"2025-05-15",{"date":139,"type":21},"2028-12",{"name":141,"class":45},"University of Michigan",2,{"id":144,"slug":4,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":149,"targetDuration":4,"studyType":22,"phases":151,"briefSummary":152,"conditions":153,"keywords":154,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":168},"100499246","NCT05780762","Impact of an Intervention Integrating the MPHS Nursing Model of Care on the Partnership in Health, With the Patient Followed in Primary Care by an Advanced Practice Nurse (APN) for One or More Stabilized Chronic Pathologies","IMPACT","Inclusion Criteria:\n\n* A patient receiving care from an advanced practice nurse (APN) for the management of one or more of the following chronic conditions: stroke; chronic arterial disease; heart disease, coronary artery disease; type 1 diabetes and type 2 diabetes; chronic respiratory failure; Parkinson's disease; epilepsy.\n* Care provided by an IPA falls under one of the following categories:\n\nEither as direct care when the IPA practices within a healthcare facility, in accordance with current regulations, Or as care referred or prescribed by a physician when the IPA practices in private practice.\n\n* Affiliated or entitled to a social security plan\n* Having received informed information about the study and having co-signed, with the investigator, a consent to participate in the study\n\nExclusion Criteria:\n\n\\- A patient who is not under the care of a nurse practitioner under the conditions set forth in the Public Health Code (lack of authorized direct access or a required physician referral, depending on the practice model).",{"count":150,"type":21},420,[24],"The WHO and our governance advocate that health professionals should organize care around the patient, considering his or her values, needs and preferences, and enabling the patient to develop the capacity to self-manage the chronic health problems he or she faces. Chronic disease is an ongoing dynamic process and adaptation to this process is complicated by the interaction of several determinants: self-management capacity, level of health literacy, quality of life and experience of care. To best support chronic disease, the recommendation is to adopt a management strategy that allows chronic patients to play an active role in the management of their condition and in the day-to-day decision-making process. The management of chronic pathologies is one of the specialties in which Advanced Practice Nurses are positioned, in primary care, outside hospital. Nursing care benefits from care models that allow for more adapted responses, regarding particular care situations, or certain patient typologies. The Humanistic Partnership Health Care Model (MPHS) implement in current Advanced Practice Nurse (APN) practice.",[27],[155,156,157,158],"advanced practice nurse (APN)","patient partnership","health literacy","self-management","2026-06-08",{"date":161,"type":38},"2026-06-10",{"date":163,"type":38},"2024-04-12",{"date":165,"type":21},"2028-11-30",{"name":167,"class":45},"Centre Hospitalier Universitaire de Saint Etienne",5,{"id":170,"slug":4,"hasResults":11,"nctId":171,"briefTitle":172,"officialTitle":172,"acronym":4,"eligibilityCriteria":173,"healthyVolunteers":11,"sex":17,"minAge":174,"maxAge":4,"enrollmentInfo":175,"targetDuration":4,"studyType":22,"phases":177,"briefSummary":178,"conditions":179,"keywords":181,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":112},"100639938","NCT07589673","Development and Evaluation of an Online Shared Decision-Making Educational Program for Nurses and Patients With Chronic Diseases","Inclusion Criteria for Nurse:\n\n* Registered nurses currently providing direct patient care in participating general hospitals\n* Able to understand the purpose and procedures of the study and provide informed consent\n* Able to use a computer, tablet, or smartphone to access the online program\n\nExclusion Criteria for Nurse:\n\n* Not currently engaged in direct patient care\n* Unable to clearly express willingness to participate\n* Unable to complete the educational program or questionnaires because of technical or language limitations\n\nInclusion Criteria for Patients:\n\n* Adults aged 19 years or older living in the community\n* Diagnosed with one or more chronic diseases requiring ongoing management, including but not limited to hypertension, diabetes mellitus, dyslipidemia, arthritis, chronic respiratory disease, or cardiovascular disease, with at least 3 months elapsed since diagnosis\n* Able to understand the purpose and procedures of the study and provide informed consent\n* Able to read and respond to survey questions\n* Able to use a computer, tablet, or smartphone to access the online program\n\nExclusion Criteria for Patients:\n\n* Cognitive impairment or communication problems that make participation difficult\n* Unable to complete the educational program or questionnaires because of technical or language limitations","19 Years",{"count":176,"type":21},288,[24],"This study aims to develop and evaluate an online shared decision-making (SDM) educational program for nurses and patients with chronic diseases. Shared decision-making is a process in which healthcare professionals and patients make health-related decisions together based on the best available evidence and the patient's values and preferences. The study includes an evaluation phase. In the evaluation phase, the program will be tested among nurses working in general hospitals and adults with chronic diseases living in the community. Outcomes related to shared decision-making will be assessed at baseline, immediately after the 4-week program, and 1 month later. The study is expected to improve shared decision-making competence, experience, and preparedness among both nurses and patients.",[27,180],"Shared Decision-making",[182,183,184,185],"Shared decision-making","Chronic disease","Online education","Decision support","2026-05-21",{"date":188,"type":38},"2026-05-26",{"date":190,"type":21},"2026-05-10",{"date":192,"type":21},"2027-04-03",{"name":194,"class":45},"Chungnam National University",{"id":196,"slug":4,"hasResults":11,"nctId":197,"briefTitle":198,"officialTitle":199,"acronym":4,"eligibilityCriteria":200,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":201,"targetDuration":4,"studyType":22,"phases":203,"briefSummary":204,"conditions":205,"keywords":207,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":4},"100637731","NCT07594418","Phenotype-Guided Weaning in Mechanically Ventilated Patients With Chronic Comorbidities","Effect of a Phenotype-Guided Precision Intervention Strategy on 28-Day Ventilator-Free Days in Mechanically Ventilated Patients With Chronic Comorbidities: A Multicenter Open-Label Randomized Controlled Trial","Inclusion Criteria:\n\n1. Age 18 years or older.\n2. Presence of at least one chronic cardiovascular, cerebrovascular, or respiratory comorbidity. Cardiovascular and cerebrovascular comorbidities include stroke, hypertension, ischemic heart disease, valvular heart disease, heart failure, pulmonary heart disease, cardiomyopathy, and arrhythmia. Respiratory comorbidities include chronic obstructive pulmonary disease, asthma, bronchitis, emphysema, interstitial lung disease, and pneumoconiosis. These conditions will be identified according to the International Classification of Diseases 11th Revision diagnosis codes.\n3. Receiving invasive mechanical ventilation for at least 24 hours and expected to require mechanical ventilation for at least 72 hours.\n4. Not receiving neuromuscular blocking agents and having a Richmond Agitation-Sedation Scale score of -3 or higher.\n5. PaO2\u002FFiO2 of 150 mmHg or higher.\n\nExclusion Criteria:\n\n1. Severe neuromuscular disease, such as Guillain-Barre syndrome, myasthenia gravis, amyotrophic lateral sclerosis, multiple sclerosis, or high spinal cord injury.\n2. Severe dysfunction of other organs with expected death in the short term.\n3. Severe end-stage irreversible respiratory, cardiac, neurological, or malignant disease, or receiving palliative care.\n4. Pregnancy.\n5. Participation in another clinical study.\n6. Written informed consent not provided.",{"count":202,"type":21},1380,[24],"The goal of this clinical trial is to learn whether a phenotype-guided weaning strategy can help adults with chronic comorbidities be liberated from invasive mechanical ventilation earlier. It will also learn about the safety of this strategy.\n\nThe main questions it aims to answer are:\n\n* Does the phenotype-guided weaning strategy increase the number of ventilator-free days within 28 days after enrollment?\n* Does the strategy improve the process and success of ventilator liberation?\n* What safety events occur when this strategy is used?\n\nResearchers will compare the phenotype-guided weaning strategy with standard care in mechanically ventilated patients with chronic cardiovascular, cerebrovascular, or respiratory comorbidities.\n\nIn the intervention period, participants will receive a protocolized ventilator weaning pathway. This pathway includes assisted ventilation transition, daily weaning readiness screening, a 0 cmH2O continuous positive airway pressure test, spontaneous breathing trial, extubation assessment, and post-extubation respiratory support when appropriate.\n\nThe phenotype-guided part of the strategy is mainly used for participants who fail a spontaneous breathing trial or have difficult weaning. These participants will undergo structured ABCDE screening to identify the main phenotype or mechanism of weaning failure:\n\n* A: airway or lung dysfunction\n* B: brain dysfunction, including delirium, anxiety, agitation, or impaired consciousness\n* C: cardiac dysfunction\n* D: diaphragm or respiratory muscle dysfunction\n* E: endocrine, metabolic, or nutritional problems\n\nBased on the identified phenotype, clinicians will provide targeted assessment and treatment. Participants will be followed for ventilator-free days through day 28 and for clinical outcomes through day 90.",[206,27],"Mechanical Ventilation Weaning",[208,209,210,211,212,213],"Phenotype-Guided Weaning","Ventilator Liberation","Ventilator-Free Days","Chronic Comorbidities","Spontaneous Breathing Trial","ABCDE Screening","2026-05-17",{"date":216,"type":38},"2026-05-19",{"date":218,"type":21},"2026-09",{"date":220,"type":21},"2027-11",{"name":222,"class":45},"Southeast University, China",{"id":224,"slug":4,"hasResults":11,"nctId":225,"briefTitle":226,"officialTitle":227,"acronym":4,"eligibilityCriteria":228,"healthyVolunteers":53,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":229,"targetDuration":4,"studyType":22,"phases":230,"briefSummary":231,"conditions":232,"keywords":233,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":112},"100625460","NCT07422922","Click & Pick Study","A Longitudinal, Randomized-Controlled Experiment of Healthy Food Policies in Online Retail Settings","Inclusion Criteria:\n\n* ≥18 years old\n* Not currently eligible for or participating in SNAP or another government program that automatically qualifies the person for SNAP (e.g., WIC, TANF)\n* Meets the following income eligibility requirements:\n\nFor participants living in the Houston or San Antonio areas, their household income must be greater than 165% of the federal poverty level, but less than the Texas state median household income (based on the 2023 American Community Survey) for their household size \\[11\\].\n\nFor participants living in the Philadelphia area, their income must be greater than 200% of the federal poverty level, but less than the Pennsylvania state median household income (based on the 2023 American Community Survey) for their household size \\[11\\].\n\n* Reports consuming food from McDonald's or a similar fast-food chain at least once a month\n* Does most of the grocery shopping for the household\n* Can adhere to the study schedule (e.g., receive a lunch on a Wednesday)\n* Has regular internet access\n* Has a smart phone that can take pictures\n* Resident of Houston, TX, San Antonio, TX or Philadelphia, PA or the surrounding areas and plans to be there for the next six weeks\n* Household size of six or fewer people\n* Have an address eligible for receiving Grubhub+ and Walmart+ deliveries\n\nExclusion Criteria:\n\n* Does not meet all of the inclusion criteria\n* Cognitive impairment; per PIs discretion\n* Participant is under 18 years old\n* Does not speak English or Spanish",{"count":121,"type":21},[24],"Unhealthy diets significantly contribute to major preventable chronic diseases including type 2 diabetes, obesity, heart disease and stroke, which disproportionally impact racial\u002Fethnic minority groups and those with lower income \\[1-3\\]. Although taxes and warning labels targeting sugar-sweetened beverages (SSB) have been successful at shifting behavior \\[4-7\\], there are many other ultra-processed food products that contribute to unhealthy diets \\[8\\]. What is less well-known is whether a suite of healthy food policies that are expanded to target a range of ultra-processed foods can shift dietary choices and intake in meaningful ways. Our research team's long-term goal is to identify and understand the degree to which combinations of healthy food policies can improve nutrition security and reduce nutrition-related diseases.",[27],[102,234,235,97,236,237,238,239,240],"behavioral economics","warning label","ultra-processed food","unhealthy food","sugar-sweetened beverage","advertisement restriction","nutrition policy","2026-05-15",{"date":243,"type":38},"2026-05-18",{"date":245,"type":38},"2026-02-25",{"date":247,"type":21},"2028-04-21",{"name":249,"class":45},"University of Pennsylvania",{"id":251,"slug":4,"hasResults":11,"nctId":252,"briefTitle":253,"officialTitle":254,"acronym":255,"eligibilityCriteria":256,"healthyVolunteers":11,"sex":17,"minAge":119,"maxAge":257,"enrollmentInfo":258,"targetDuration":260,"studyType":56,"phases":4,"briefSummary":261,"conditions":262,"keywords":265,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":269,"lastUpdatePostDateStruct":270,"startDateStruct":271,"completionDateStruct":272,"leadSponsor":274,"locationsCount":112},"100639542","NCT07592962","Whole-life Investigation of Lishui Longevity","Whole-life Investigation of Lishui Longevity Cohort Study","WILL","Inclusion Criteria:\n\n* Aged 30 to 80 years old; male-to-female ratio of 1:1; permanent residents in Lishui City; physically healthy; voluntary participation in the project with signed informed consent.\n\nExclusion Criteria:\n\n* Individuals ever diagnosed with malignant tumors or cardiovascular and cerebrovascular diseases by physicians or other health professionals; those with unstable vital signs or an expected survival time of less than 3 months; participants with incomplete basic information, and those unable to cooperate with subsequent follow-up.","80 Years",{"count":259,"type":21},4500,"10 Years","1. To establish a standardized, normalized and scientific joint screening and follow-up management system for chronic disease multimorbidity in Lishui City, and early identify common risk factors of major chronic diseases such as cardiovascular and cerebrovascular diseases and tumors.\n2. To carry out targeted intervention and long-term follow-up for high-risk populations, reduce the incidence risk of major chronic diseases in the target population, improve residents' health status and grassroots comprehensive prevention and treatment capacity of chronic diseases, and provide scientific evidence and practical support for the construction of Healthy Lishui.",[263,27,264],"Ischemic Stroke","Cardiovascular",[266,267,268],"acute ischemic stroke","carotid artery stenosis","Hepatic fibrosis","2026-05-12",{"date":243,"type":38},{"date":243,"type":21},{"date":273,"type":21},"2036-05-31",{"name":275,"class":45},"The Fifth Affiliated Hospital of Wenzhou Medical University & Lishui Central Hospital",{"id":277,"slug":4,"hasResults":11,"nctId":278,"briefTitle":279,"officialTitle":280,"acronym":4,"eligibilityCriteria":281,"healthyVolunteers":11,"sex":17,"minAge":282,"maxAge":283,"enrollmentInfo":284,"targetDuration":4,"studyType":22,"phases":286,"briefSummary":287,"conditions":288,"keywords":293,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":297,"lastUpdatePostDateStruct":298,"startDateStruct":300,"completionDateStruct":302,"leadSponsor":304,"locationsCount":4},"100614494","NCT07280325","Moxie Self-Management and Education Support Program","Moxie: A Self-management Education and Support Program Using Advertising Principles to Reduce Rehospitalization for Cardiovascular-related Illnesses","Inclusion Criteria:\n\nEligible participants will be adults aged 40-85 years who are being discharged to their home from general internal medicine or family medicine inpatient services (hospitalist) in one of 10 Alberta acute care facilities, whose admitting diagnosis was diabetes, coronary artery disease, heart failure, chronic kidney disease, or hypertension (see appendix for list of inclusion diagnoses).\n\nExclusion Criteria:\n\nIndividuals who live at the same address\u002Fhousehold as a person who is already in the study and\u002For those discharged from hospitals to continuing care facilities, rehabilitation facilities or another hospital will not be eligible to take part in the study. Individuals whose goals of care at the time of discharge from acute care were oriented towards comfort (i.e. C1 or C2 Goals of Care) will not be eligible to take part in the study. Individuals with markers indicating lack of competency\u002Fcapacity in their inpatient ConnectCare record such as anything but full capacity on the medical record (i.e. \"incapacitated\" or \"needs review\"), or presence of an alternative decision maker, agent, or legal guardian listed on the medical record.","40 Years","85 Years",{"count":285,"type":21},9000,[24],"Health education and self-management support are key facilitators of health behaviours. Moxie is a mixed media, self-management, education and support program for Albertans living with cardiovascular-related chronic conditions. Moxie is built upon our previous work within the ACCESS study (2015-21, n=4761), a RCT that previously tested the Moxie intervention in Alberta. Results demonstrated that MOXIE reduced the rate of hospitalizations (notably for hypertension, angina, hyper\u002Fhypoglycemia, heart failure decompensation, and acute kidney complications) by 34% in a population of low-income seniors living with cardiovascular-related chronic conditions.\n\nHowever, before Moxie can be effectively implemented province-wide, another trial is necessary to determine whether benefits can be observed in a larger cohort of patients with cardiovascular-related chronic conditions recruited immediately after hospital discharge (n=9000). Furthermore, the effectiveness of the two components of the ACCESS trial intervention will be assessed individually:\n\n(a) The Moxie Program, a tailored health and disease education component developed by a user-experience-centric design process incorporating patients, behavioural scientists, disease specialists, health system administrators and marketing\u002Fadvertising professionals; and (b) the facilitated relay of clinical information to healthcare providers (letters).\n\nThe trial is designed as a 2x2 factorial pragmatic, individual-level randomized pragmatic trial of these different interventions. This would yield the following groups:\n\n1. Moxie SMES Program\n2. Facilitated Relay\n3. Moxie SMES Program and Facilitated Relay\n4. True control\n\nSelf-management education and support (SMES) intervention: This includes weekly physical mailers sent directly to patients' homes throughout the study containing information about chronic conditions, medication use, diet, physical activity, smoking cessation, and self-management\u002Fwellness principles. These messages will be refined by the social impact creative design partner and reviewed by clinicians and patients to ensure clinical safety and appropriate tone. Weekly mailers will encourage participants to enroll and consent to participate in the digital program by scanning a QR code or accessing a website where they will sign up for their own personalized Moxie mobile health app, complete a digital consent form and opt-in for electronic delivery of Moxie messages.\n\nFacilitated relay intervention: Participants allocated to this intervention will receive letters by mail, one addressed to them, one to their primary care provider, and one to their pharmacist. The letters will not be sent to their primary care provider directly; rather, they will be sent to patients who will be encouraged to take them to their primary care provider and pharmacist should they decide to do so. We hope this will empower patients to start discussions with their healthcare providers. This also supports patient autonomy by enabling patients to decide whether they want to take them to their provider or not. If for whatever reason they do not feel that this is going to be beneficial or of interest, they are not required to do so. The letter would contain a note to the patient's healthcare provider stating that their patient is at-risk of cardiovascular disease and that evidence has shown that the pharmacotherapy is effective in improving outcomes for patients similar to the participant.\n\nThe primary outcome is readmission for cardiovascular-specific ambulatory care-sensitive conditions (ACSC) based on the most responsible diagnosis listed in CIHI Discharge Abstract Database-(DAD), using established algorithms within 12 months from randomization. This outcome includes all repeat admissions in the study period as recorded in the health record. This outcome is a count variable. We will calculate and compare each intervention arm's mean number and distribution of hospitalizations.",[289,290,291,292,27],"Chronic Kidney Disease","Diabetes (DM)","Heart Disease","Stroke",[294,295,296],"Chronic Disease Self-Management","Pragmatic Trial","Chronic Disease Education","2026-05-08",{"date":299,"type":38},"2026-05-11",{"date":301,"type":21},"2026-06-01",{"date":303,"type":21},"2029-12-31",{"name":305,"class":45},"University of Calgary",{"id":307,"slug":4,"hasResults":11,"nctId":308,"briefTitle":309,"officialTitle":310,"acronym":311,"eligibilityCriteria":312,"healthyVolunteers":53,"sex":17,"minAge":119,"maxAge":313,"enrollmentInfo":314,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":316,"conditions":317,"keywords":333,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":347,"lastUpdatePostDateStruct":348,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":354,"locationsCount":112},"100346729","NCT03794531","Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico","Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic Disease Trends","PROSPECT","Inclusion Criteria:\n\n1. Age 30-75 years old at the time of enrollment\n2. Non-institutionalized\n3. Living in PR at the time of the first interview and the year before and not planning to move from the island within 3 years\n4. Able to answer questions without assistance\n5. Living in a stable dwelling\n\nExclusion Criteria:","75 Years",{"count":315,"type":21},2500,"The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing cardiovascular-related disparities in Puerto Rico. To this end, investigators will establish 'PROSPECT: Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic disease Trends', an island-wide, longitudinal population cohort of 2,500 adults (30-75 years) in PR recruited with a community-wide sampling strategy, and assessed in a network of several partner clinics across the island. The study will collect comprehensive data on multiple psychosocial, dietary, and food-related factors, CVD biological markers, and medical record data, with follow-up at 2-years, and will assess variations by urban-rural area and by timing before-after Maria.",[318,319,320,321,322,323,324,27,325,326,327,328,329,330,331,332],"Heart Diseases","Type2 Diabetes","Hypertension","Obesity","Dyslipidemias","Metabolic Syndrome","Cardiovascular Diseases","Inflammation","Psychological Stress","Physiological Stress","Depressive Symptoms","Coping Behavior","Diet Habit","Lifestyle","Food Insecurity",[334,335,336,337,338,339,340,341,342,343,344,345,346],"Hispanics\u002FLatinos","Minority health","Puerto Rico","Cardiovascular disease","Cardiometabolic health","Chronic disease risk factors","Disaster research","Caribbean and Latin America","Population health","Prospective study","Allostatic load","Food insecurity","Longitudinal study","2026-04-30",{"date":349,"type":38},"2026-05-05",{"date":351,"type":38},"2019-03-01",{"date":353,"type":21},"2029-04-30",{"name":355,"class":45},"Harvard School of Public Health (HSPH)",{"id":357,"slug":4,"hasResults":11,"nctId":358,"briefTitle":359,"officialTitle":360,"acronym":361,"eligibilityCriteria":362,"healthyVolunteers":11,"sex":17,"minAge":363,"maxAge":4,"enrollmentInfo":364,"targetDuration":4,"studyType":22,"phases":366,"briefSummary":367,"conditions":368,"keywords":371,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":377,"lastUpdatePostDateStruct":378,"startDateStruct":380,"completionDateStruct":382,"leadSponsor":384,"locationsCount":112},"100621217","NCT07367750","Testing the Feasibility of a Self-Management Support Program for Patient With Chronic Diseases in Israel","Implementation of a Self-Management Support Program Among People With Kidney Transplant and Cancer Survivors in Israel: Testing Feasibility and Effects","CDSMP-IL","Inclusion Criteria:\n\n* Age 21 years or older\n* Diagnosed with at least one chronic disease (as documented in the medical record)\n* Community-dwelling\n* Fluent in Hebrew\n\nExclusion Criteria:\n\n* Documented cognitive impairment\n* Diagnosis of major depression or other psychiatric disorder (based on self-report or medical records)\n* Hospitalization in the past 3 months","21 Years",{"count":365,"type":21},45,[24],"This study explores an intervention to support people in Israel who are living with chronic health conditions such as cancer or after kidney transplantation. It focuses on a well-known international program called the Chronic Disease Self-Management Program (CDSMP), which was developed at Stanford University. The program helps individuals build confidence and skills to better manage their health, feel more in control, and improve their day-to-day quality of life.\n\nParticipants will take part in a six-week group program, delivered online, where they will learn practical strategies for managing symptoms like fatigue or pain, setting achievable health goals, communicating effectively with healthcare professionals, and staying active and engaged. The sessions are guided by trained facilitators and include support from others facing similar health challenges.\n\nThe study will involve surveys before and after the program, as well as a follow-up six months later, to understand how the program may have helped participants. Some participants will also be invited to share their experiences in small discussion groups.\n\nBy testing this program in Israel, the researchers hope to learn how it can be adapted and offered more widely to help others living with chronic conditions.",[27,369,370],"Kidney Transplantation","Cancer Survivorship",[27,372,373,374,375,376],"Self-Management","CDSMP","Kidney","Transplantation","Cancer Survivors","2026-04-28",{"date":379,"type":38},"2026-04-29",{"date":381,"type":38},"2025-02-01",{"date":383,"type":21},"2027-03-28",{"name":385,"class":45},"University of Haifa",{"id":387,"slug":4,"hasResults":11,"nctId":388,"briefTitle":389,"officialTitle":390,"acronym":4,"eligibilityCriteria":391,"healthyVolunteers":53,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":392,"targetDuration":394,"studyType":56,"phases":4,"briefSummary":395,"conditions":396,"keywords":398,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":406,"lastUpdatePostDateStruct":407,"startDateStruct":409,"completionDateStruct":411,"leadSponsor":413,"locationsCount":112},"100634581","NCT07541547","Adult Disease Risk Prediction Using Wearables, Hearing, and Health Data","A Study to Build a Disease Risk Prediction Model for Adults by Integrating Data From Wearable Devices, Hearing Tests, and Multiple Health Databases","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Living in the community in Taiwan\n* Able to understand the study procedures and provide written informed consent\n* Able and willing to complete the study questionnaire, hearing assessment, and wearable device monitoring procedures\n* Has access to a smartphone and is able to install and use the study-related application, with assistance from study staff if needed\n\nExclusion Criteria:\n\n* Diagnosis of dementia\n* Too frail or has other health conditions that make participation in the study procedures not feasible\n* Bilateral deafness without use of any hearing assistive device\n* Does not have a smartphone or is unable to use a smartphone application required for the study procedures",{"count":393,"type":21},1500,"2 Weeks","This prospective cohort study aims to develop and validate a personalized disease risk prediction model for adults by integrating multiple sources of health data. The study will recruit community-dwelling adults aged 18 years and older in Taiwan. After providing informed consent, participants will complete a structured questionnaire, undergo pure tone hearing testing, and wear a smartwatch for 2 weeks to collect continuous physiological data, including heart rate and physical activity. With participant authorization, the study will also collect data from personal health records and national health insurance databases to allow longer-term follow-up of health outcomes.\n\nThe main goals of the study are to examine the relationships among hearing, lifestyle factors, and wearable device data; to identify combinations of risk factors associated with progression from health to subclinical or chronic disease states; and to develop analytical methods for integrating heterogeneous health data from questionnaires, physiological monitoring, hearing tests, and medical databases. Machine learning methods will be used to identify important predictors and build risk prediction models.\n\nThe study hypothesis is that combining hearing measures, lifestyle information, wearable physiological data, and longitudinal medical record data will improve the ability to identify individuals at higher risk of future disease compared with using a single source of information alone. The long-term objective is to support early risk identification, personalized health management, and prevention strategies in community adults.",[27,397],"Risk Assessment",[399,397,27,400,401,402,403,404,405],"Wearable Devices","Disease Prediction","Machine Learning","Cohort Studies","Physiological Monitoring","Personal Health Records","Health Insurance Claims","2026-04-13",{"date":408,"type":38},"2026-04-21",{"date":410,"type":38},"2026-01-09",{"date":412,"type":21},"2029-01",{"name":414,"class":45},"National Health Research Institutes, Taiwan",{"id":416,"slug":4,"hasResults":11,"nctId":417,"briefTitle":418,"officialTitle":419,"acronym":420,"eligibilityCriteria":421,"healthyVolunteers":11,"sex":17,"minAge":422,"maxAge":423,"enrollmentInfo":424,"targetDuration":4,"studyType":22,"phases":426,"briefSummary":427,"conditions":428,"keywords":435,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":445,"lastUpdatePostDateStruct":446,"startDateStruct":448,"completionDateStruct":449,"leadSponsor":451,"locationsCount":112},"100634174","NCT07536256","Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being","Kamaehu o ke Kaiāulu: Fostering Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being","Kamaehu","Inclusion Criteria:\n\n* youth 12 to 25 years of age;\n* live in the Wai'anae zip code 96792;\n* utilize Waianae Coast Comprehensive Health Center (WCCHC) for their healthcare, including the WCCHC School-based Health Centers;\n* assessed by WCCHC providers as being \"at-promise\" or having a physical or behavioral\u002Fmental health concern that may benefit from further support from Kaiona CBO Programs. Conditions may include chronic disease risk factors such as asthma, obesity, diabetes, or prediabetes, as well as behavioral health concerns.\n\nExclusion Criteria:\n\n* Rather than strict exclusionary criteria, we will rely on the onboarding process that allows for screening for program fit at 4 levels: the referring Pediatric\u002FBehavioral Health provider, the Community Connections Manager, the youth participant\u002Ffamily member, and the receiving CBO. All 4 of these levels will need to assess a potential participant as fit to participate. General considerations include ability to work in groups with other youth, ability to be outdoors for hours at a time, and ability to receive basic instruction and complete basic physical and cognitive tasks associated with the program independently. All 4 layers will also have the opportunity to end the youth's participation in the program at any point if serious safety or health concerns arise for the participant or others involved in the program. If a participant needs to leave a program, the Community Connections Manager will remain engaged with the youth and family to explore other options through the pilot or elsewhere.","12 Years","25 Years",{"count":425,"type":21},100,[24],"The goal of this pilot clinical trial is to learn if a community referral program can improve services for youth with mental health and chronic health conditions in a predominantly Native Hawaiian and Pacific Islander community. The main questions the trial aims to address are:\n\n* What is the best way for a community health center to connect youth with community programs rooted in cultural practices and traditions?\n* Does participation in community programs engage youth and mental health and chronic health outcomes?\n\nParticipants will:\n\n* Participate in a community program for youth that will strengthen connection to 'āina (land) and culture. Programs in the summer are 5 hours per day, 4 days a week, for 4 weeks. Programs in the school-year are 2.5 hours per day, 2 days a week, for 16 weeks.\n* Take surveys on their demographics, general well-being, mental health, and chronic health conditions they may have at 4 different times: Before the program begins, immediately after the program finishes, 3-4 months after finishing, and 6-8 months after finishing.\n* Have an adult family member complete surveys on their youth's demographics and general well-being at the same 4 times",[27,429,430,431,432,433,434],"Adolescent Asthma","Obesity & Overweight","Youth Mental Health","Youth Obesity","Prediabetes","Asthma",[436,437,438,439,440,441,442,443,444],"Adolescent Health Services","Community Health Centers","Mental Health Services","Native Hawaiian or Other Pacific Islander","Community Health Services","Adolescent","Young Adult","Child","youth mental health","2026-04-10",{"date":447,"type":38},"2026-04-17",{"date":445,"type":38},{"date":450,"type":21},"2028-08-31",{"name":452,"class":45},"Waianae Coast Comprehensive Health Center",{"id":454,"slug":4,"hasResults":11,"nctId":455,"briefTitle":456,"officialTitle":457,"acronym":4,"eligibilityCriteria":458,"healthyVolunteers":53,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":459,"targetDuration":4,"studyType":22,"phases":461,"briefSummary":462,"conditions":463,"keywords":472,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":478,"lastUpdatePostDateStruct":479,"startDateStruct":481,"completionDateStruct":483,"leadSponsor":485,"locationsCount":112},"100619127","NCT07340580","Implementation Facilitation of Exercise is Medicine Greenville","Facilitating Health System Implementation of Physical Activity Screening and Referral to Community-Based Programs: Exercise is Medicine Greenville","The primary aim of this study is implementation facilitation at the clinic level. The secondary aim of this study is at the patient level. Therefore we have divided our inclusion\u002Fexclusion eligibility criteria by primary and secondary aim.\n\n1\\. Clinic (primary aim) Inclusion criteria\n\n* Currently EIMG-activated Prisma Health-Upstate Primary Care clinic (family or internal medicine)\n* Adopted EIMG \\>= 6 months prior to the beginning of this study\n\nExclusion criteria\n\n* Not EIMG-activated\n* Adopted EIMG \\\u003C 6 months prior to the beginning of this study\n* Greater than 15 miles from the nearest YMCA\n\n  1\\. Primary care clinic staff (primary aim) Inclusion criteria\n* At least 18 years of age\n* Has worked at the Prisma Health-Upstate clinic since the start date of the intervention in the respective wave, i.e., Pre-IF start date for each wave\n* Has clinical encounters with a minimum of 25 patients per month\n* Study clinic is their primary clinic (\\>50% of their working time)\n* Able to understand and communicate in English\n\nExclusion criteria\n\n* Less than 18 years of age\n* Work at the Prisma Health-Upstate clinic started after the Pre-IF phase began\n* Has clinical encounters with \\\u003C25 patients per month\n* Unable to speak or understand English\n* Adults unable to provide consent\n\n  2\\. Patient (secondary aim) Inclusion criteria (must meet all of below)\n* Age \\>= 18 and \\\u003C= 80 years\n* Clinically eligible (diagnosis of hypertension, dyslipidemia, obesity, diabetes, or physical inactivity) to receive an EIMG referral\n* A healthcare visit with an eligible encounter type (evaluation, telemedicine, consult, office visit, e-visit, follow-up, appointment, education, multidisciplinary visit, nutrition, occupational medicine-office visit)\n* A healthcare visit at a participating clinic\n\nExclusion criteria\n\n* Age \\\u003C 18 or \\> 80 years\n* Current referral to Physical therapy or occupational therapy\n* Current referral to cardiac, pulmonary, or oncology rehab\n* One of the following visit diagnoses listed below:\n\n  * Alzheimer's disease\n  * Amyotrophic lateral sclerosis\n  * angina or chest pain\n  * congenital stenosis of aortic valve\n  * congenital insufficiency of aortic valve\n  * moderate or severe persistent asthma\n  * typical or atypical atrial flutter\n  * autonomic dysreflexia\n  * acute bronchitis\n  * cerebral infarction\n  * encounter for chemotherapy\n  * chronic kidney disease (stage 3-5)\n  * end stage renal disease\n  * coma\n  * acute chronic obstructive pulmonary disease\n  * unspecified dementia\n  * dependence on renal dialysis\n  * trisomy 21\n  * pulmonary embolism\n  * venous embolism and thrombosis\n  * history of falling\n  * acute fracture\n  * left ventricular failure\n  * congestive heart failure\n  * hypertensive urgency, emergency or crisis\n  * diabetes with ketoacidosis\n  * chronic respiratory failure\n  * dependence on supplemental oxygen\n  * myocardial infarction\n  * osteoporosis with current fracture\n  * encounter for palliative care\n  * paraplegia or quadriplegia\n  * Parkinson disease\n  * pneumonia\n  * encounter for supervision of pregnancy\n  * encounter for radiation therapy\n  * serious mental illness (schizophrenia, psychotic disorder)\n  * homicidal or suicidal ideations\n  * sepsis\n  * injury of spinal cord\n  * presence of coronary stent\n  * dependence on wheelchair or ambulatory aid\n\nFor patients completing accelerometry data collection, the additional inclusion\u002Fexclusion criteria apply:\n\nInclusion criteria:\n\n* Received an EIMG referral and scheduled for orientation\n* Attending orientation at two pre-determined community PA facilities (these sites were selected due to each being the largest urban and rural YMCA referral sites in the study)\n\nExclusion criteria:\n\n* Unable to provide verbal informed consent\n* Planning on travel or vacation during data collection, as patient PA behavior is anticipated to differ from 'everyday' PA behavior at home\n* Unable to wear a watch during work hours due to employment restrictions e.g., food service, healthcare, operating heavy machinery\u002Fconstruction, laboratory-based work etc.\n\nIn addition, for patients completing interviews, the additional inclusion\u002Fexclusion criteria apply:\n\nInclusion criteria:\n\n\\- Received an EIMG referral\n\nExclusion criteria:\n\n* Unable to provide verbal informed consent\n* Unable to speak or understand English\n* \\\u003C18 years of age",{"count":460,"type":21},35,[24],"A public health priority exists for the U.S. healthcare sector to integrate physical activity (PA) as a part of the patient care model. This research will provide valuable information on facilitating optimal implementation of a clinic-to-community model that identifies, refers, and enrolls physically inactive patients to community-based PA programs for the prevention and treatment of chronic diseases. Further, this work will provide evidence on the cost-effectiveness of integrating PA in healthcare systems as a population health management strategy.",[464,465,466,320,85,467,468,27,469,470,471],"Physical Inactivity","Dyslipidemia","Obesity and Overweight","Health Care Delivery","Patients","Exercise","Physical Activity","Implementation Science",[473,474,475,476,477],"Implementation Facilitation","Physical activity referral scheme","Effectiveness-implementation hybrid type 3","Pragmatic design","Stepped wedge","2026-03-27",{"date":480,"type":38},"2026-04-02",{"date":482,"type":21},"2026-05-01",{"date":484,"type":21},"2030-07-31",{"name":486,"class":45},"University of South Carolina",{"id":488,"slug":4,"hasResults":11,"nctId":489,"briefTitle":490,"officialTitle":490,"acronym":491,"eligibilityCriteria":492,"healthyVolunteers":53,"sex":17,"minAge":493,"maxAge":4,"enrollmentInfo":494,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":496,"conditions":497,"keywords":498,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":506,"lastUpdatePostDateStruct":507,"startDateStruct":509,"completionDateStruct":511,"leadSponsor":513,"locationsCount":112},"100427639","NCT04848623","Identification of Vocal Biomarkers to Monitor the Health of People With a Chronic Disease","CoLive Voice","Inclusion Criteria:\n\n* Adolescents and adults \\> 15 years\n* With or without health conditions\n* From all countries\n\nExclusion Criteria:\n\n* Children \\\u003C 15 years","15 Years",{"count":495,"type":21},50000,"The CoLive Voice research project aims to identify vocal biomarkers of severe conditions and frequent health symptoms. The project is based on digital technologies and statistical algorithms. This is an international anonymous survey where vocal recordings are collected simultaneously with large validated clinical and epidemiological data, in the context of various chronic diseases or frequent health symptoms in the general population.",[27],[499,500,501,502,503,504,505],"vocal biomarker","digital biomarker","digital health","artificial intelligence","telemonitoring","medical devices","precision health digital biomarker","2026-03-24",{"date":508,"type":38},"2026-03-30",{"date":510,"type":38},"2021-06-26",{"date":512,"type":21},"2031-05-01",{"name":514,"class":515},"Luxembourg Institute of Health","OTHER_GOV",{"id":517,"slug":4,"hasResults":11,"nctId":518,"briefTitle":519,"officialTitle":520,"acronym":521,"eligibilityCriteria":522,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":523,"targetDuration":4,"studyType":22,"phases":525,"briefSummary":526,"conditions":527,"keywords":532,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":541,"lastUpdatePostDateStruct":542,"startDateStruct":543,"completionDateStruct":544,"leadSponsor":546,"locationsCount":4},"100631070","NCT07495891","Sustainability of the Effects of an Adapted Physical Activity Program on Physical Fitness and Psycho-behavioral Factors in Patients With Chronic Diseases","Sustainability of the Effects of an Adapted Physical Activity Program on Physical Fitness and Psycho-behavioral Factors in Patients With Chronic Diseases: the Influence of Program Duration and the Use of a Smartwatch","DURATECH-APA","Inclusion Criteria:\n\n* Patients over the age of 18\n* French-speaking patients\n* Patients with a chronic condition diagnosed by a doctor\n* Patients with a doctor's prescription for APA\n* Patients capable of understanding instructions\n* Patients enrolled in the Social Security system\n* Patients referred to Maison Sport Santé La Musse by a doctor for the first time\n\nNon inclusion Criteria :\n\n* Medical contraindications to physical exertion\n* Pregnant women\n* Individuals under legal guardianship, conservatorship, or judicial protection.\n* Severe cognitive or motor impairment\n* Lack of proficiency in French\n* Patients in the acute phase requiring specialized care\n* Patients simultaneously participating in another interventional research study\n* Inability to attend sessions regularly or adhere to the schedule of evaluations.\n* Patients who have already completed a program at the Maison Sport Santé\n\nExclusion Criteria:\n\n* Completion of fewer than 16 APA sessions (less than 70% of sessions)\n* Acute exacerbation of a chronic condition during follow-up\n* For groups without smartwatches, the use of a digital tool such as a physical activity tracker by participants would constitute an exclusion criterion\n* Completion of a patient therapeutic education program",{"count":524,"type":21},280,[24],"This study aims to determine the extent to which different approaches to adapted physical activity coaching influence physical fitness, psycho-behavioral, and anthropometric parameters in patients with stabilized chronic conditions who have been referred to a Sport-Health Center by their physician. The trial includes four parallel groups, distinguishing between two program durations (3 months or 6 months) and the use or non-use of a smartwatch as a tool for monitoring activity. All participants complete 24 sessions of adapted physical activity (APA), in accordance with the standard practices of the La Musse Sport-Health Center, where the study is entirely conducted. However, the distribution of sessions differs by group: two sessions per week over three months or one session per week over six months. Randomization is stratified by age, sex, and baseline fitness level. Assessments are conducted at the following five time points: enrollment (T0), end of the 3-month program (T1), end of the 6-month program (T2), followed by follow-up at 12 months (T3) and 18 months (T4), to observe the durability of the effects after the supervised phase. The primary outcome measure is improvement in physical fitness and anthropometric parameters, objectively measured using tests recognized for their reliability (TDM6, Sit-to-Stand 30s, Timed Up and Go, Sit and Reach, grip strength, BMI, waist circumference). The secondary outcomes focus on changes in motivation toward health-related physical activity (EMAPS), perceived self-efficacy to engage in physical activity (ECS), and self-reported physical activity (IPAQ-SF), which will be collected regularly throughout the program, more frequently than in standard care. A total of 280 patients will be enrolled to ensure sufficient statistical power, taking into account an anticipated loss-to-follow-up rate over 18 months. Data collection and processing will be pseudonymized and conducted on the secure network of La Musse Hospital.",[528,529,27,530,531],"Adapted Physical Activity","Smartwatches","Motivation for Physical Activity","Physical Fitness",[533,534,535,536,537,538,539,540],"Adapted physical activity","Chronic diseases","Smartwatch","Sustainability of effects","Motivation for physical activity","Self-efficacy in physical activity","Physical fitness","Longitudinal follow-up","2026-03-23",{"date":478,"type":38},{"date":508,"type":21},{"date":545,"type":21},"2028-12-31",{"name":547,"class":45},"Hopital La Musse",{"id":549,"slug":4,"hasResults":11,"nctId":550,"briefTitle":551,"officialTitle":551,"acronym":552,"eligibilityCriteria":553,"healthyVolunteers":53,"sex":554,"minAge":18,"maxAge":4,"enrollmentInfo":555,"targetDuration":4,"studyType":22,"phases":557,"briefSummary":558,"conditions":559,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":562,"lastUpdatePostDateStruct":563,"startDateStruct":565,"completionDateStruct":567,"leadSponsor":569,"locationsCount":571},"100571739","NCT06724172","CHIME: Comparing Health Interventions for Maternal Equity","CHIME","Inclusion Criteria:\n\n* Maternal age 18 years or older\n* Maternal gestational age ≤ 20 weeks with viable singleton pregnancy documented on first trimester ultrasound with an intention to continue pregnancy to term\n* Plans to continue receiving antenatal care at the recruitment site\u002Fnetwork\n* Maternal characteristics include at least one of the following:\n* Self identifies as Black\u002FAfrican American\n* Self identifies as Hispanic\u002FLatino\u002Fa\u002Fe\u002Fx\n* Insured by Medicaid\n* Maternal ability to speak English or Spanish\n* Completion of baseline data collection (maternal survey data, weight, and height measurement prior to randomization)\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years at baseline because of unique developmental differences of adolescents and regulations regarding age of consent\n* Underweight (BMI \\\u003C18 kg\u002Fm2) at pre-pregnancy period\n* Underlying disease\u002Ftreatment that might impact weight status (e.g., significant gastrointestinal conditions, major psychiatric disorders, and others at the discretion of the study clinician)\n* Unwillingness or inability to complete study visits or intervention components\n* Unwillingness or inability to commit to intervention components for self or infant, including plans to move more than 100-mile radius from recruitment site\n* Multiple gestations","FEMALE",{"count":556,"type":21},795,[24],"The goal of this comparative effectiveness trial is to compare how three different approaches to overcome barriers to resources and provide nutrition and physical activity counseling improve maternal healthy weight in pregnancy and postpartum.\n\nThe main question it aims to answer is which of the two multi-level, multi-component interventions has greater effectiveness in reducing maternal postpartum weight retention at 12-months postpartum.\n\nHypothesis (primary): Both multi-level, multi-component interventions will have greater effectiveness reducing maternal postpartum weight retention at 12-months postpartum than the usual care group.\n\nHypothesis (secondary): The community-based intervention will have greater effectiveness than the self-management intervention.\n\nParticipants will be asked to participate in one of the study interventions from early pregnancy until 12 months postpartum and complete five research visits. General procedures include completion of:\n\n* Questionnaires\n* Dietary recalls\n* In-depth interviews\n* Anthropometric measurements\n* Collection of blood via finger stick or blood panel",[466,560,27,85,561],"Nutrition","Pregnancy","2026-03-03",{"date":564,"type":38},"2026-03-05",{"date":566,"type":38},"2026-01-22",{"date":568,"type":21},"2030-04-01",{"name":570,"class":45},"Stanford University",4,{"id":573,"slug":4,"hasResults":11,"nctId":574,"briefTitle":575,"officialTitle":576,"acronym":577,"eligibilityCriteria":578,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":579,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":580,"conditions":581,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":591,"lastUpdatePostDateStruct":592,"startDateStruct":594,"completionDateStruct":596,"leadSponsor":598,"locationsCount":4},"100623008","NCT07391046","Integrating Vaccination Into Hospital Care Pathways for Vulnerable Patients","Integrating Vaccination Into Hospital Care Pathways for Vulnerable Patients: A Scalable and Sustainable Model","AMBU-VAX","Inclusion Criteria:\n\n* Adults aged ≥18 years\n* Presence of at least one chronic or immunocompromising condition eligible for vaccination according to national guidelines\n* Written informed consent provided\n\nExclusion Criteria:\n\n* Age \\\u003C18 years\n* Conditions not included among the predefined eligibility criteria",{"count":393,"type":21},"AMBU-VAX is a prospective, single-center observational study designed to develop and implement an organizational model for delivering recommended vaccinations within a hospital setting.\n\nThe study targets adult and elderly patients with chronic diseases or immunocompromising conditions who are eligible for vaccination according to national immunization guidelines. Vaccination is actively proposed during outpatient visits, hospital admissions, or at discharge and, when accepted, administered within the hospital or coordinated with local public health vaccination services.\n\nThe study aims to evaluate the feasibility, uptake, and completion of hospital-based vaccination pathways and to support integration between hospital and territorial prevention services for vulnerable populations.",[27,582,583,289,584,585,586,587,588,589,590],"Immunocompromised","HIV Infection","Solid Organ Transplantation","Hematopoietic Stem Cell Transplantation","Cancer","Autoimmune Diseases","Inflammatory Bowel Disease","Asplenia","Frailty","2026-01-29",{"date":593,"type":38},"2026-02-05",{"date":595,"type":21},"2026-02",{"date":597,"type":21},"2027-02",{"name":599,"class":45},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS",{"id":601,"slug":4,"hasResults":11,"nctId":602,"briefTitle":603,"officialTitle":604,"acronym":4,"eligibilityCriteria":605,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":606,"targetDuration":4,"studyType":22,"phases":608,"briefSummary":609,"conditions":610,"keywords":611,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":615,"lastUpdatePostDateStruct":616,"startDateStruct":617,"completionDateStruct":619,"leadSponsor":620,"locationsCount":112},"100586505","NCT06916247","Evaluation of AI Cost Prediction Model to Enroll Patients in Complex Care Management Program","Evaluation of MA Proactive Care Program Using Cost Prediction Model With Randomized Waitlist","Inclusion Criteria:\n\n* At least 18 years of age\n* Enrolled in a UCLA Managed Care Plan\n* Cost prediction model identifies patient as having high predicted costs over the next 12 months\n\nExclusion Criteria:\n\n* Currently enrolled in any UCLA care management program\n* Enrolled in any UCLA care management program in the last 12 months\n* Already has an active referral to a care management program",{"count":607,"type":21},5000,[24],"Currently, UCLA Health (specifically the Office of Population Health and Accountable Care, or OPHAC) runs a complex care management program called Proactive Care (goal is to reduce care utilization by providing personalized care navigation\u002Fcase management). Every month, an AI Population Risk tool runs to identify around 250 of the 480,000 or so UCLA primary care patients, and RNs contact these 250 patients to enroll in Proactive Care. Starting in December 2024, OPHAC launched a new method of enrolling UCLA's Medicare Advantage (MA) patients into Proactive Care: an AI Cost Prediction model. The idea is the same-- the top 250 highest predicted cost patients will be enrolled in Proactive Care. The investigators will evaluate this model and subsequent enrollment into the program by randomizing the waitlist of MA patients waiting to enroll in Proactive Care, thereby creating a control group. The top 500 highest predicted cost patients will be identified each month, and following a 1:1 randomization, 250 will be contacted for enrollment and the rest will be put on a wait-list control group for 10 months unless otherwise requested by their provider to be enrolled in the Proactive Care program earlier.",[27],[612,613,614],"High utilization","Complex care management","Cost prediction model","2026-01-27",{"date":591,"type":38},{"date":618,"type":38},"2024-08-16",{"date":269,"type":21},{"name":621,"class":45},"University of California, Los Angeles",{"id":623,"slug":4,"hasResults":11,"nctId":624,"briefTitle":625,"officialTitle":626,"acronym":4,"eligibilityCriteria":627,"healthyVolunteers":53,"sex":17,"minAge":628,"maxAge":629,"enrollmentInfo":630,"targetDuration":4,"studyType":22,"phases":632,"briefSummary":633,"conditions":634,"keywords":638,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":641,"lastUpdatePostDateStruct":642,"startDateStruct":643,"completionDateStruct":645,"leadSponsor":647,"locationsCount":112},"100618362","NCT07330635","Chronic Wounds and Blood Circulation Detection","Constructing a Holistic Care New Model for Chronic Wounds and Blood Circulation Detection to Enhance Home Care Quality","Inclusion Criteria:\n\nGeneral criteria (applied to all participants):\n\nWillingness to participate in this study and comply with all study procedures. Able to perform basic physical activity and complete lower limb circulatory and functional assessments.\n\nNormal cognitive function sufficient to understand instructions and provide informed consent.\n\nGroup-specific criteria:\n\nYoung Adults (Control Group):Aged 20-40 years.No known chronic diseases or peripheral circulatory disorders.Considered healthy volunteers.\n\nOlder Adults (Healthy Elderly Group):Aged 65-95 years.No major chronic diseases affecting lower limb circulation.\n\nOlder Adults with Chronic Disease (Impaired Circulation Group):Aged 65-95 years.Diagnosed with one or more conditions known to impair peripheral circulation, including but not limited to peripheral arterial disease (e.g., atherosclerosis, thromboangiitis obliterans), chronic venous insufficiency (e.g., varicose veins), diabetes mellitus, hypertension, or hyperlipidemia.\n\nExclusion Criteria:\n\nRecent acute lower limb injury resulting in tissue exudation, swelling, or other conditions that prevent safe participation in the assessment or intervention procedures.","20 Years","95 Years",{"count":631,"type":21},425,[24],"Lower limb circulatory insufficiency and the associated chronic wounds are common health problems among the elderly. These issues not only affect the individual's mobility and quality of life but also potentially increase medical costs and caregiving expenses. Traditional treatment methods often employ medications to enhance blood circulation, but these clinical approaches have limited effectiveness and induce the risk of side effects. Utilizing exercise as an intervention strategy can help improve lower limb blood circulation in the elderly while reducing the side effects associated with medications. However, due to physical frailty, elderly individuals often cannot participate in high-intensity exercises to improve their circulatory performance.\n\nTherefore, this study will develop a lower limb circulation enhancement exercise system to improve the circulatory performance in individuals with poor lower limb circulation. It will compare the effects of lower limb circulation enhancement exercise, vibration exercise, and mixed exercise on improving blood circulation and functional performance in the elderly or individuals with poor lower limb circulation.\n\nParticipants will be randomly assigned into three groups: the lower limb circulation enhancement exercise group, the vibration exercise group, and the mixed exercise group. In addition, a separate group of young adults (control group) will serve as a reference for baseline comparisons. Initially, all participants will undergo a one-time exercise test, followed by a 12-week intervention. The lower limb circulation enhancement exercise group will perform a 30-minute leg press rowing exercise three times a week, while the vibration exercise group will engage in vibration exercise at the same frequency, and the mixed exercise group will perform group-based mixed exercise training at the same frequency. The young adult control group will not receive any intervention but will undergo the same assessments.\n\nOutcome evaluations before and after the intervention include lower limb blood perfusion monitoring, pain scales, and functional performance assessments.",[635,636,637,27],"Aging","Walking, Difficulty","Chronic Limb-Threatening Ischemia",[639,640,27],"Poor Lower Limb Circulation","Older Adults","2025-12-29",{"date":410,"type":38},{"date":644,"type":38},"2024-09-04",{"date":646,"type":21},"2027-12-31",{"name":414,"class":45},{"id":649,"slug":4,"hasResults":11,"nctId":650,"briefTitle":651,"officialTitle":652,"acronym":653,"eligibilityCriteria":654,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":655,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":656,"conditions":657,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":658,"lastUpdatePostDateStruct":659,"startDateStruct":661,"completionDateStruct":663,"leadSponsor":664,"locationsCount":666},"100596055","NCT07040475","Effects of the Clinical Application of Traditional, Complementary and Integrative Medicine (TCIM) Procedures During Inpatient Stays in Germany","Effects of the Clinical Application of TCIM Procedures During Inpatient Stays in Germany - a Multicenter Observational Study","Minerva","Inclusion criteria:\n\n* Beginning (first 24 hours) inpatient TCIM treatment at Immanuel Hospital Berlin, Bamberg Hospital, or Evangelische Kliniken Essen-Mitte\n* Written consent form\n\nExclusion criteria:\n\n* Insufficient language skills\n* Dementia or other severely impairing cognitive disorders\n* Pregnancy or breastfeeding\n* Participation in a clinical study",{"count":315,"type":21},"The aim of this healthcare research project is to evaluate the effects of routine inpatient TCIM (Traditional, Complementary and Integrative Medicine) care in Germany. The focus is on the TCIM centers at Immanuel Krankenhaus Berlin, Klinikum Bamberg und Evang. Kliniken Essen-Mitte, where inpatient TCIM therapies are to be systematically evaluated. This form of therapy, which is reimbursed by statutory health insurance providers (under certain conditions), is based on a combination of various evidence-based TCIM approaches. These include hyperthermia, exercise therapy, Mind-Body Medicine, phytotherapy, nutritional therapy, fasting therapy inter alia.",[27],"2025-12-19",{"date":660,"type":38},"2025-12-26",{"date":662,"type":38},"2025-07-01",{"date":646,"type":21},{"name":665,"class":45},"Charite University, Berlin, Germany",3,{"id":668,"slug":4,"hasResults":11,"nctId":669,"briefTitle":670,"officialTitle":670,"acronym":671,"eligibilityCriteria":672,"healthyVolunteers":53,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":673,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":675,"conditions":676,"keywords":680,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":684,"lastUpdatePostDateStruct":685,"startDateStruct":686,"completionDateStruct":688,"leadSponsor":690,"locationsCount":112},"100616646","NCT07308314","Taining Golden Lake Comprehensive Chronic Disease Management Initiative","TAIGOLD-CDM","Inclusion Criteria:\n\n* Age ≥18 years, male or female.\n* Resident of Taining County for ≥6 months and expected to remain in the county for at least the next 3 years.\n* Full civil capacity and able to understand study procedures.\n* Willing to voluntarily participate and provide written informed consent.\n* Able to complete baseline survey and follow-up visits.\n\nExclusion Criteria:\n\n* Refusal to sign informed consent.\n* Severe psychiatric disorders or cognitive impairment preventing participation.\n* End-stage disease with expected survival \\\u003C1 year.\n* Long-term migrants (≥6 months per year outside the county), unable to guarantee follow-up.\n* Participation in other clinical studies that may interfere with this research.",{"count":674,"type":21},20000,"This study aims to establish the first county-level, population-based prospective cohort in Taining County, Fujian Province, China. The cohort will include at least 20,000 residents aged 18 years or older. The project will systematically collect questionnaires, physical measurements, laboratory tests, imaging data, and biological samples to build a multi-dimensional health database and biobank. Through 3-year follow-up, the study seeks to reveal the epidemiological patterns and risk factors of chronic diseases, characterize the natural course of multimorbidity and aging syndromes, and develop a comprehensive chronic disease management model suitable for rural and mountainous regions.",[27,677,320,678,322,590,679],"Chronic Disease Management","Diabetes Mellitus","Sarcopenia",[677,681,320,678,465,682,590,679,635,683],"Prospective Cohort","Cardiovascular Disease","Healthy Aging","2025-12-15",{"date":641,"type":38},{"date":687,"type":38},"2025-08-01",{"date":689,"type":21},"2028-07-01",{"name":691,"class":45},"First Affiliated Hospital of Fujian Medical University",{"id":693,"slug":4,"hasResults":11,"nctId":694,"briefTitle":695,"officialTitle":696,"acronym":4,"eligibilityCriteria":697,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":698,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":699,"conditions":700,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":702,"lastUpdatePostDateStruct":703,"startDateStruct":705,"completionDateStruct":707,"leadSponsor":709,"locationsCount":112},"100374820","NCT04160429","Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving Meditations","Pilot Study to Evaluate Substances in Sweat, Saliva, and Blood","Inclusion Criteria:\n\n* Scheduled to receive medications including, but not limited to, cyclophosphamide, mycophenolic acid, mycophenolate mofetil, metformin or busulfan (any dose, any number of doses, any dosing frequency) as part of treatment at any time. Patients with chronic or infectious diseases can participate\n* Willingness to:\n\n  * Provide blood, sweat, and saliva samples\n  * Permit medical record review\n\nExclusion Criteria:\n\n* Pilocarpine allergy\n* Difficulty with understanding written English",{"count":425,"type":21},"This trial collects and analyzes sweat and saliva samples compared to blood in detecting chemical concentrations in the body in patients with chronic or infectious diseases receiving medications. Wearable sweat sensors are capable of monitoring electrolytes and metabolites (sodium, potassium, glucose, lactate, etc.) for health monitoring and disease diagnosis. Designing wearable sweat sensors capable of providing information regarding drug administration may be challenging due to ultralow concentrations in biofluids. This trial seeks to determine if the use of a smart wristband can accurately measure the levels of chemicals and substances in sweat.",[27,701],"Infectious Disorder","2025-11-06",{"date":704,"type":38},"2025-11-10",{"date":706,"type":38},"2018-11-09",{"date":708,"type":21},"2029-07-30",{"name":710,"class":45},"City of Hope Medical Center",{"id":712,"slug":4,"hasResults":11,"nctId":713,"briefTitle":714,"officialTitle":715,"acronym":716,"eligibilityCriteria":717,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":313,"enrollmentInfo":718,"targetDuration":4,"studyType":22,"phases":720,"briefSummary":721,"conditions":722,"keywords":723,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":733,"lastUpdatePostDateStruct":734,"startDateStruct":736,"completionDateStruct":738,"leadSponsor":740,"locationsCount":142},"100553302","NCT06484322","Strategies Empowering Activities in Everyday Life: An Internet-based Occupational Therapy Intervention","Strategies Empowering Activities in Everyday Life (SEE 2.0); A Feasibility Evaluation of an Internet-based Occupational Therapy Intervention","SEE2:0","Inclusion Criteria:\n\n* Diagnosed with, or at risk of developing, a chronic disease\u002Flong-term condition such as long-term pain, stress-related conditions, chronic fatigue syndrome, rheumatological diseases, lung diseases, or neurological conditions.\n* Age: 18-75 years\n* Experiencing difficulties to have an active everyday life and\u002For experiencing a need to develop self-management strategies in everyday life.\n* Have access to a screen\u002Fcomputer, internet and e-ID as well as being able to use them\n* Be able to participate in the program, including be ready for a process of change\n* Understanding of the Swedish language in written and oral form.\n\nExclusion Criteria:\n\n* Sickness or disease which causes difficulties with understanding written and verbal advice (e.g. mental or cognitive illness).\n* Having an ongoing misuse\n* Receiving palliative care",{"count":719,"type":21},40,[24],"The purpose of the study is to evaluate the feasibility, potential outcomes and the implementation process of a second updated version of an internet-based intervention in occupational therapy, focusing on self-management in activities of everyday life to promote health in people with chronic diseases.",[27],[183,724,725,726,727,728,729,730,731,732],"Self-management","Activities of daily life","Internet-based","Tele-rehabilitation","E-health","Occupational therapy","Prevention","Rehabilitation","Long-term health conditions","2025-09-11",{"date":735,"type":38},"2025-09-17",{"date":737,"type":38},"2024-09-10",{"date":739,"type":21},"2027-06-01",{"name":741,"class":45},"Luleå Tekniska Universitet",""]