[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"clinical-high-risk\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:clinical-high-risk":86},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,57],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100575602",false,"NCT06774417","Digital Strategies to Advance Help-Seeking - Aim 3","Digital Strategies to Advance Help-Seeking in Youth at Clinical High Risk for Developing Psychosis","Inclusion Criteria:\n\n* Ages 12-29 years\n* Living within a 50-mile radius of a US based AMP-SCZ site\n* Able to complete the English language PQ-B on MHA's screening platform","ALL","12 Years","29 Years",{"count":19,"type":20},25000,"ESTIMATED","INTERVENTIONAL",[23],"NA","This proposal aims to establish a Digital Laboratory focused on advancing help-seeking and expediting treatment initiation in youth ages 12-29 who are at Clinical High-Risk (CHR) for developing psychosis. Leveraging the Health Action Process Approach (HAPA) model, this study will identify help-seeking subtypes in 25,000 youth who screen positive for psychosis-risk on Mental Health America's national online screening platform, iteratively develop and test theory and data-driven, personalized strategies to advance help-seeking using Micro-Randomized Trials and a Sequential Multiple Assignment Randomized Trial, identify the most accurate CHR screening threshold in an online environment, and link youth, when indicated, to local clinical care via AMP-SCZ, a NIH funded national network of CHR programs throughout the US. This academic-industry partnership aims to curate one of the largest datasets of youth with CHR, and to develop effective strategies to enhance early help-seeking, in a population where help-seeking is critical and a significant barrier to care.",[26,27,28],"Clinical High Risk","Early Psychosis","First Episode Psychosis","RECRUITING","2026-06-16",{"date":32,"type":33},"2026-06-18","ACTUAL",{"date":35,"type":33},"2026-02-02",{"date":37,"type":20},"2028-05-31",{"name":39,"class":40},"Columbia University","OTHER",1,{"id":43,"slug":4,"hasResults":10,"nctId":44,"briefTitle":45,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":46,"targetDuration":4,"studyType":47,"phases":4,"briefSummary":48,"conditions":49,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":56,"locationsCount":41},"100575603","NCT06774430","Digital Strategies to Advance Help-Seeking Aim 1 and 2",{"count":19,"type":20},"OBSERVATIONAL","This proposal aims to establish a Digital Laboratory focused on advancing help-seeking and expediting treatment initiation in youth ages 12-29 who are at Clinical High-Risk (CHR) for developing psychosis. Leveraging the Health Action Process Approach (HAPA) model, this study will identify help-seeking subtypes in 25,000 youth who screen positive for psychosis-risk on Mental Health America's national online screening platform, iteratively develop and test theory and data-driven, personalized strategies to advance help-seeking using Micro-Randomized Trials and a Sequential Multiple Assignment Randomized Trial, identify the most accurate CHR screening threshold in an online environment, and link youth, when indicated, to local clinical care via Accelerating Medicines Partnership - Schizophrenia (AMP-SCZ), a NIH funded national network of CHR programs throughout the US. This academic-industry partnership aims to curate one of the largest datasets of youth with CHR, and to develop effective strategies to enhance early help-seeking, in a population where help-seeking is critical and a significant barrier to care.",[26,27,28],"2026-04-30",{"date":52,"type":33},"2026-05-05",{"date":54,"type":33},"2025-04-07",{"date":37,"type":20},{"name":39,"class":40},{"id":58,"slug":4,"hasResults":10,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":10,"sex":15,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":21,"phases":67,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":41},"100469846","NCT05398120","Skills Group for Youth at Clinical High-Risk for Psychosis","Testing the Feasibility of a Skills Group for Adolescents and Young Adults at Clinical High-risk for Psychosis","Participant Inclusion Criteria:\n\n* 13-18 years of age\n* Meet criteria for clinical high-risk syndrome (i.e., at clinical high risk for developing a psychotic disorder). CHR status is determined based off of scoring a 3 (moderate) - 5 (severe) on the Structured Interview for Psychosis-Risk Syndromes and\u002For having a first degree relative with psychotic disorder and\u002For the individual meets criteria for schizotypal personality disorder. Additionally individuals with a brief intermittent psychotic symptoms can be included as well (e.g., frankly psychotic symptoms that are very brief)\n* Individuals must be enrolled in the HOPE team at the University of Pittsburgh since this group is embedded within that service\n\nParticipation Exclusion Criteria:\n\n* Group member meeting criteria for a current\u002Fpast psychotic disorder\n\nInclusion Criteria for Parents or Legal Guardians:\n\n* Must be the parent, legal guardian of a 13-18 year-old\n* For parents of CHR adolescents, their adolescent must meet criteria for a psychosis-risk syndrome","13 Years","18 Years",{"count":66,"type":20},30,[23],"This study is intended to test the feasibility of an integrated cognitive behavioral therapy (CBT) and dialectical behavioral therapy (DBT) skills group for adolescents and young adults at clinical high-risk (CHR) for psychosis. The current study applies a skills group drawing from evidence-based practices (e.g., cognitive behavioral therapy (CBT), dialectical behavioral therapy (DBT)) to those at CHR for psychosis. Up to 30 CHR individuals (starting with a minimum of 3 participants, N accounts for attrition as well), aged 13-18, already receiving clinical services within the HOPE team at University of Pittsburgh will be offered a weekly skills group. Data collected on feasibility and outcome measures will occur pre (within 1 month) -post (up to 4-5 months) and half-way (up to 2-3 months) through the intervention. Taken together, the aim of the proposed intervention is to provide novel insights regarding the utility of a newly developed intervention that integrates both CBT and DBT skills for those at CHR for psychosis.",[70,71],"Clinical High-Risk","Psychological",[73,74,75,76],"Group intervention","Dialectical behavioral therapy skills","Cognitive behavioral therapy skills","Psychosis-risk","2026-02-06",{"date":79,"type":33},"2026-02-10",{"date":81,"type":33},"2022-04-26",{"date":83,"type":20},"2026-12-31",{"name":85,"class":40},"University of Pittsburgh",""]