Cognitive Impairments

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Review clinical trials related to Cognitive Impairments. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

TIS for Improving Cognitive Impairment in Schizophrenia

This study aims to evaluate the efficacy, safety, and underlying neural mechanisms of TIS targeting the hippocampus in ameliorating cognitive impairment associated with schizophrenia (CIAS). Researchers will compare active TIS to a sham control to see if TIS works to treat CIAS. Participants will receive TIS twice a day for 2 weeks. Their clinical data, including the baseline clinical symptom scale score, cognitive function, E/I imbalance index recorded by EEG, and MRI data, will be collected at baseline, at the end of the 2-week intervention, and 4 weeks after the intervention.

Participants needed: 50
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: Central South UniversityUpdated: Jun 15, 2026Locations: 1
Eligibility criteria

Age 18-50 years old; [+8]

Presence of other psychiatric comorbidities, intellectual disability, obvious mo... [+6]

Status: Recruiting

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

This Phase III trial will examine the efficacy of computerized cognitive training methods on perceived cognitive impairment in breast cancer survivors.

Participants needed: 386
Trial details
Age: 18-100Biological sex: AllType: InterventionalSponsor: NRG OncologyUpdated: Apr 23, 2026Locations: 680
Eligibility criteria

The participant must provide study-specific informed consent prior to any study... [+4]

Scoring less than or equal to 3 on the 6-item cognitive screen. [+9]

Status: Not yet recruiting

The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine Users

The study aims to address the neurobiological basis of cognitive impairments in chronic cocaine users by investigating the potential impact of an acute potassium channel blockade on working memory performance and other cognitive functions.

Participants needed: 40
Trial details
Age: 20-50Biological sex: AllType: InterventionalSponsor: Boris QuednowUpdated: Apr 20, 2026Locations: 1
Eligibility criteria

Current diagnosis of mild, moderate, or severe CoUD according to DSM-5 [+9]

Presence or history of severe neurological disorders or head injuries [+19]

Status: Recruiting

Psychiatric Status and Symptom Severity in Graft-versus-Host Disease (GvHD).

This prospective observational study evaluates the association between psychiatric status, GvHD-related symptom severity, and health-related quality of life in patients with graft-versus-host disease. Standardized and validated assessment tools, including the Lee Symptom Scale, will be used to collect psychiatric, clinical, and demographic data.

Participants needed: 200
Trial details
Age: 18-75Biological sex: AllType: ObservationalSponsor: Medical University of GdanskUpdated: Jan 2, 2026Locations: 1Duration: 1 Year
Eligibility criteria

Adult patients with a clinically established diagnosis of graft-versus-host dise...

Severe psychiatric disorders precluding adequate cooperation, terminal-stage mul...