[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"corneal-melting-in-boston-keratoprosthesis-type-i\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:corneal-melting-in-boston-keratoprosthesis-type-i":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100288987",false,"NCT03041883","Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting","Corneal Collagen Crosslinking to Increase the Resistance of the Graft Used as a Support for the Boston Keratoprosthesis Type I Against Corneal Melting","CXL-KPro","Inclusion Criteria:\n\n* Candidate for KPro type I\n* Capacity to give written consent\n* Ability to be followed for the duration of the study\n\nExclusion Criteria:\n\n* Participation in another interventional study\n* Failure to wear a therapeutic contact lens due to abnormalities of the eyelids.\n* Inability to give written consent\n\nContraindications to the KPro type I:\n\n* Severe dryness with keratinization of the ocular surface\n* Intraocular tumor\n* Terminal glaucoma\n* Inoperable retinal detachment\n* Phthisis bulbi","ALL","18 Years","80 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to demonstrate the safety and efficacy of the corneal collagen crosslinking with riboflavin and ultraviolet A in aim to increase the resistance of the graft used as a support for the Boston keratoprosthesis (KPro) type I against corneal melting (keratolysis or sterile necrosis).",[27],"Corneal Melting in Boston Keratoprosthesis Type I","RECRUITING","2026-04-24",{"date":31,"type":32},"2026-04-28","ACTUAL",{"date":34,"type":32},"2017-01-04",{"date":36,"type":21},"2028-01",{"name":38,"class":39},"Centre hospitalier de l'Université de Montréal (CHUM)","OTHER",""]