Distal Radius Fracture

19

Review clinical trials related to Distal Radius Fracture. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Wrist Injury Strengthening Exercise (WISE) Versus Usual Care Advice for Improving Pain and Function

The goal of this clinical trial is to find out whether a therapist-guided exercise program helps people aged 50 and older recover better, in terms of pain and function, after a wrist fracture, compared to the usual care advice they would normally receive. The main question it aims to answer is: • Will participants who receive a therapist-supervised exercise program have better improvement in pain and function, as measured by the Patient Rated Wrist Evaluation questionnaire, six months after their injury? Researchers will compare these participants with those who receive usual care, which includes advice on self-management, to see if the supervised exercise program leads to greater recovery. Participants will: * Either receive supervised exercise, with a therapy session of up to 60 minutes and two additional sessions of up to 30 minutes each in addition to usual-care, or they will receive solely usual-care, consisting of advice on self-management. * Complete questionnaires electronically at baseline, 3-months, and 6-months.

Participants needed: 588
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: University of AarhusUpdated: Jun 30, 2026Locations: 1
Eligibility criteria

Distal radius fracture treated surgically or non-surgically [+1]

Injury is more than two months old [+3]

Status: Not yet recruiting

Kinesiophobia and Functional Outcomes in Distal Radius Fractures

Distal radius fractures are among the most common fractures in adults and are frequently treated with closed reduction and cast immobilization. Although fracture healing is generally successful, some patients may develop fear of movement (kinesiophobia) after cast removal because of pain, reinjury concerns, or reduced confidence in using the injured wrist. The purpose of this study is to evaluate the level of kinesiophobia in adults with conservatively treated distal radius fractures and to investigate how kinesiophobia changes over time following cast removal. The study will also examine the relationship between kinesiophobia and functional recovery. Participants will be assessed after cast removal and again at three months following injury. Kinesiophobia, pain intensity, hand and wrist function, range of motion, grip strength, and upper extremity disability will be evaluated using standardized assessment tools. The findings may help clinicians better understand the role of movement-related fear in recovery and support the development of rehabilitation strategies aimed at improving functional outcomes after distal radius fractures.

Participants needed: 100
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Ebru Aloğlu ÇiftçiUpdated: Jun 25, 2026
Eligibility criteria

Age range: 18-65 years [+4]

History of previous fracture or neurological pathology in the same extremity [+3]

Status: Recruiting

Satisfaction and Recovery After Distal Radius Fracture

Distal radius fracture is the most common fracture in Sweden, but little is known about the patient's experience of pain and hand function during the first three months after the injury. This observational study will provide detailed information on a daily basis regarding pain, use of analgesic drugs, use of splints and hand function as measured weekly by a condition-specific questionnaire.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Sahlgrenska University HospitalUpdated: Apr 24, 2026Locations: 2
Eligibility criteria

Unilateral distal radius fractures in patients without any other significant inj... [+1]

Compound injuries [+4]

Status: Recruiting

The Investigation of Kinesiophobia in Conservative Distal Radius Fractures

This study aimed to investigate the predictability of kinesiophobia on functional outcomes in conservatively treated patients with distal radius fractures. For this purpose, patients' level of kinesiophobia will be assessed using the Tampa Kinesiophobia Scale. To assess the functional status of patients, joint range of motion and upper extremity weight bearing measurements will be performed. Patients' functionality will be additionally assessed with the Patient Rated Wrist Evaluation Questionnaire.

Participants needed: 34
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Pamukkale UniversityUpdated: Mar 10, 2026Locations: 2Duration: 18 Weeks
Eligibility criteria

Having been treated conservatively with an isolated distal radius fracture diagn... [+1]

Comorbid musculoskeletal-neurovascular injuries [+1]

Status: Recruiting

Hematoma Block for Distal Radius Fracture

The purpose of this study is to determine the efficacy of ultrasound guided hematoma block versus traditional "blind" hematoma block for analgesia in distal radius fracture reduction.

Participants needed: 115
Trial details
Age: 18-100Biological sex: AllType: InterventionalSponsor: Beth Israel Deaconess Medical CenterUpdated: Mar 3, 2026Locations: 1
Eligibility criteria

Adult patient ≥ 18 years old presenting to the emergency department with complai...

High acuity/distress per the Attending ED physician [+3]

Status: Recruiting

Home-Based Photobiomodulation Effects in the Postoperative Period of Distal Radius Fractures

This double-blind, randomized controlled clinical trial aims to evaluate the adjuvant effect of home-based photobiomodulation (PBM) therapy on the rehabilitation of surgically treated DRFs combined with an unsupervised home exercise program. A total of 42 participants will be randomly allocated into two groups. The Control Group will undergo the standard surgical procedure, perform the prescribed home exercises recommended by the hospital service, and use an inactive LED plate (photobiomodulation device). The PBM Group will follow the same surgical and exercise protocols but will use an active PBM device. Home exercises will begin 24 hours after surgery and should be performed twice daily for a total of 12 weeks. The device will be applied once daily to the wrist for 12 minutes (6 minutes on the dorsal side and 6 minutes on the palmar side). The primary outcome will be functional wrist assessment using the QuickDASH (Quick Disabilities of the Arm, Shoulder, and Hand) questionnaire at 2 weeks. Secondary outcomes will include wrist range of motion, grip strength, wrist function, and pain (assessed using the PRWE-BR instrument), as well as fracture healing. Assessments will be performed at 2, 4, 6, and 12 weeks post-surgery, except for bone consolidation (assessed starting at week 4) and for pain and range of motion, which will also be evaluated at 24 hours.

Participants needed: 42
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: University of Nove de JulhoUpdated: Feb 23, 2026Locations: 1
Eligibility criteria

Adults aged 18 to 65 years, [+8]

Previous wrist injuries, sequelae, or motor deficits due to neurological lesions... [+9]

Status: Recruiting

Impact of Early ADL Participation on Outcomes Post DRF

This study is a randomized controlled trial (RCT). This RCT which will study the effect of performing daily activities early after a distal radius fracture being treated conservatively in a cast. This study will have two groups. The experimental group will watch a video and be given a handout on how to perform daily activities with the hand of the injured wrist while in a cast and cast care. The control group will watch a video on cast care and be given a handout on cast care. Outcome measures will be taken at initial evaluation between 0-3 weeks, at 6 weeks, at 9 weeks, and at 3 months. Outcome measures will include the Michigan Wrist Evaluation, Visual Analog Pain Scale, Tampa Scale of Kinesiophobia-11 Scale, finger mobility testing, grip and pinch strength, and the 9 hole peg test to test fine motor coordination. Outcome measure scores will be compared between groups using a t-test statistical test. Outcome measure scores will also be tested within groups using a paired t-test.

Participants needed: 64
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: George Washington UniversityUpdated: Feb 12, 2026Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

No Reduction Compared to Closed Reduction for Distal Radius Fractures in Patients Over 65 or Older

DISCLOSE trial is a randomized controlled trial including 532 participants with low-energy distal radius fractures. The primary objective is to evaluate whether casting without prior closed reduction is equivalent to casting following closed reduction with respect to wrist-related pain and disability, as measured by the Patient-Rated Wrist Evaluation (PRWE) score at 12 months, in patients aged 65 years or older with a displaced distal radius fracture. * Primary endpoint will be PRWE at 12 months * Follow-up visits are scheduled at 3 and 12 months. 5-year follow-up will be considered as an exploratory endpoint

Participants needed: 532
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: Tampere University HospitalUpdated: Jan 21, 2026Locations: 10
Eligibility criteria

Age 65 years or older [+4]

Patient unable to provide consent [+8]

Status: Not yet recruiting

Minimal Clinically Important Difference of the Push-Off Test

The aim was to determine the minimal clinically important difference of the push-off test in distal radius fractures.

Participants needed: 109
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Pamukkale UniversityUpdated: Jan 14, 2026Locations: 1
Eligibility criteria

Diagnosis of distal radius fracture (DRF) and treatment with either conservative... [+3]

Presence of concomitant musculoskeletal or neurovascular injuries in the affecte... [+1]

Status: Recruiting

Quantitative and Clinical Assessment of Flexor Tendon Gliding Following Application of a Bioresorbable Hydrogel: A Prospective, Randomized Study in Patients Undergoing Distal Radius Fracture Repair

The investigators will be evaluating the use of versawrap in the setting of distal radius fractures by placing membrane between plate and flexor tendons. Investigators will then evaluate tendon gliding morphology and number of tendon ruptures

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Colorado, DenverUpdated: Oct 2, 2025Locations: 2
Eligibility criteria

Cognitively able to converse in English or in native language supported by a cer... [+1]

open injury; [+5]

Status: Not yet recruiting

Use of a Vibration Tool for Postoperative Pain Control in Distal Radius Fractures

The purpose of this research study is to determine if using a vibration tool improves pain control after surgical treatment of distal radius fracture. Additionally, the investigators would like to determine if this tool has any impact on consumption of pain medications postoperatively.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Northwestern UniversityUpdated: Sep 29, 2025Locations: 1
Eligibility criteria

Patients with a distal radius fracture who have undergone an open reduction and... [+2]

Patients undergoing oncologic surgery [+3]

Status: Not yet recruiting

Digital Aftercare for Wrist and Clavicle Fractures

This prospective, two-arm, open-label clinical trial compares digital aftercare with traditional follow-up in adult patients after surgical treatment of uncomplicated distal radius or clavicle fractures. The primary objective is to assess functional recovery at three months, using the Patient-Rated Wrist Evaluation (PRWE) for wrist fractures and the QuickDASH for clavicle fractures. Secondary outcomes include range of motion, patient satisfaction, quality of life, complication rates, healthcare costs, and work disability. In the digital aftercare group, program adherence and user experience will also be evaluated through app usage data and a structured questionnaire. The study aims to determine whether digital aftercare is a clinically and economically equivalent alternative to standard in-person care.

Participants needed: 84
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Luzerner KantonsspitalUpdated: Jul 8, 2025Locations: 1
Eligibility criteria

Age between 18 and 65 years [+4]

Polytrauma or additional injuries to the same upper extremity [+4]

Status: Not yet recruiting

RemeOs™ DrillPin for Fixation of Distal Radius Fractures in Children

This is a pre-market, single-arm, open-label, monocenter clinical investigation evaluating the safety and performance of the magnesium (Mg)-based bioresorbable RemeOs™ DrillPin for surgical fixation of distal radius fractures in pediatric patients. The study will enroll 20 children aged over 5 and under 14 years to assess implantation success, early safety outcomes, and long-term effects on growth and bone healing.

Participants needed: 20
Trial details
Age: 5-13Biological sex: AllType: InterventionalSponsor: Bioretec Ltd.Updated: Jun 19, 2025
Eligibility criteria

Distal Radius Fractures [+2]

Pathological bone lesions (e.g. bone cyst or osteomyelitis) [+7]

Status: Recruiting

Early Strengthening Rehabilitation Training for Post-operative Fracture Distal Radius

The primary objective of this study is to demonstrate safety and efficacy of an early strengthening and passive mobilization rehabilitation program for post-operative distal radius fracture fixation surgery compared to current conventional rehabilitation.

Participants needed: 50
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: The University of Hong KongUpdated: Apr 25, 2025Locations: 1
Eligibility criteria

Aged 50 years or older [+3]

History of previous hand or wrist surgery [+8]

Status: Recruiting

"Supracondylar Radial Nerve Block Guided by Ultrasound Versus Hematoma Block for Analgesic Management in Closed Reduction of Distal Radius Fractures"

Non-surgical treatment with closed reduction and immobilization using a splint or cast is the preferred approach for stable distal radius fractures, particularly in elderly patients. It is also the initial intervention for displaced fractures with a surgical indication before the procedure, aiming to reduce edema, manage pain, and prevent associated complications. However, the maneuvers required for bone reduction can cause significant pain, and there is still insufficient evidence to favor one anesthetic method over another. In recent years, there has been a trend toward utilizing local methods, such as hematoma block or ultrasound-guided supracondylar block of the radial nerve, due to their lower incidence of complications. Nonetheless, there are currently no studies comparing the efficacy of these two analgesic approaches. This study aims to compare the analgesic effect of ultrasound-guided supracondylar block with that obtained through hematoma block in patients with distal radius fracture during closed reduction, using the Numeric Rating Scale. Additionally, it aims to compare the quality of the reduction through radiographic measures and assess the frequency of adverse events after the two interventions.

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Hospital Universitario San IgnacioUpdated: Mar 17, 2025Locations: 1
Eligibility criteria

Patients over 18 years old with skeletal maturity evidenced in the initial radio... [+4]

• Patients with bilateral distal radius fractures [+8]

Status: Recruiting

The Effects of Whirlpool and Contrast Bath in Patients with Complex Regional Pain Syndrome After Distal Radius Fracture

The aim of our study is to investigate the effects of whirlpool bath and contrast bath treatments on pain, disability, functionality and grip strength in patients with complex regional pain syndrome after distal radius fracture.

Participants needed: 40
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Afyonkarahisar Health Sciences UniversityUpdated: Jan 30, 2025Locations: 1
Eligibility criteria

Patients with complex regional pain syndrome type-1 (CRPS-type 1) after distal r...

Orthopedic injuries (other accompanying orthopedic fractures, such as ulna fract... [+9]

Status: Recruiting

Fracture Registry University Hospital Basel

The primary goal of this research project is to measure the accuracy of the classifications of the distal radius fracture in the fracture database. The evaluation of the extracted data analyzes the validity of the fracture classifications that the medical staff carry out in everyday clinical practice. Endpoint of this project is the reclassification of the selected fractures by an in-house group of experts in order to be able to carry out a subsequent statistical evaluation. It is analyzed whether there are significant deviations between the classifications of the expert group and the fracture database.

Participants needed: 216
Trial details
Age: 16+Biological sex: AllType: ObservationalSponsor: University Hospital, Basel, SwitzerlandUpdated: Dec 9, 2024Locations: 1
Eligibility criteria

Patients at least 16 years of age and regardless of gender [+3]

Existence of a documented refusal [+7]

Status: Recruiting

Functional Outcome After EPL-rupture After Distal Radius Fracture

Rupture of the extensor pollicis longus, (EPL) is a common complication after distal radius fractures. A rupture prevents the thumb extension, which in turn has a negative impact on hand function. An EPL-rupture can either be surgically treated by primary suture, which means that the ends of the tendon are sutured. This is however not recommended if the tendon is weakened. In such cases the rupture can be treated by a transfer of, most often, extensor indicis proprius (EIP) to the thumb. Distal radius fractures are common and a rupture of the EPL-tendon is a known complication thar interferes with hand function and therefore more studies on this patient group are warranted. The aim of this prospective study is to compare regaining of thumb function after surgery, with the non-injured side, after primary suture and EIP-transfer after EPL-rupture as a complication following distal radius fracture.

Participants needed: 60
Trial details
Age: 16+Biological sex: AllType: ObservationalSponsor: Vastra Gotaland RegionUpdated: Nov 14, 2024Locations: 1
Eligibility criteria

Distal Radius Fracture [+1]

comorbidity interfering with thumb function [+1]

Status: Not yet recruiting

Minimally Invasive Fixation for Distal Radius Fractures

Minimally invasive surgery avoids the tissue damage and impairment of physiological function caused by open surgery because of its precise location techniques and can effectively promote the early recovery of wrist function. Under conditions of no cutting of fracture fragments, no blood supply compromise in the fracture fragments

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Assiut UniversityUpdated: Aug 5, 2024
Eligibility criteria

patients with unstable distal radial fracture [+2]

contaminated open fractures. [+1]