[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dysphotopsia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dysphotopsia":78},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,37],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":4,"maxAge":4,"enrollmentInfo":15,"targetDuration":4,"studyType":18,"phases":4,"briefSummary":19,"conditions":20,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":32,"leadSponsor":34,"locationsCount":4},"100638417",false,"NCT07577635","Impact of Iridotomy\u002FIridectomy Size on Postoperative Pupillary Block and Dysphotopsia Following DMEK","Inclusion Criteria:\n\n* Adults aged ≥ 18 years\n* Patients undergoing Descemet membrane endothelial keratoplasty (DMEK) at the Department of Ophthalmology, University Hospital Leipzig\n* Preoperative Nd:YAG laser iridotomy or intraoperative surgical iridectomy performed as part of standard care\n* Ability to provide written informed consent\n* Willingness to complete the postoperative dysphotopsia questionnaire\n\nExclusion Criteria:\n\n* Inability to provide informed consent or refusal to participate\n* Pre-existing surgical iridectomy\n* Missing or incomplete preoperative or postoperative anterior segment OCT data\n* Active anterior uveitis or panuveitis at the time of surgery","ALL",{"count":16,"type":17},100,"ESTIMATED","OBSERVATIONAL","Descemet membrane endothelial keratoplasty (DMEK) is the standard surgical treatment for corneal endothelial disorders. A postoperative pupillary block may occur despite routine preoperative laser iridotomy or intraoperative surgical iridectomy. Insufficient size or incomplete patency of the iridotomy\u002Firidectomy (IT) may contribute to this complication, while excessively large openings may be associated with postoperative dysphotopsia. This prospective observational study investigates the association between IT size measured by anterior segment optical coherence tomography (AS-OCT) and the occurrence of postoperative pupillary block and dysphotopsia after DMEK.",[21,22,23,24],"Pupillary Block After DMEK","Laser Iridotomy \u002F Surgical Iridectomy","Dysphotopsia","Descemet Membrane Endothelial Keratoplasty (DMEK)","NOT_YET_RECRUITING","2026-07-01",{"date":28,"type":29},"2026-07-02","ACTUAL",{"date":31,"type":17},"2026-06-01",{"date":33,"type":17},"2027-07-01",{"name":35,"class":36},"University of Leipzig","OTHER",{"id":38,"slug":4,"hasResults":10,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":4,"eligibilityCriteria":42,"healthyVolunteers":10,"sex":14,"minAge":43,"maxAge":4,"enrollmentInfo":44,"targetDuration":46,"studyType":18,"phases":4,"briefSummary":47,"conditions":48,"keywords":53,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":77},"100609329","NCT07213167","Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants","Clinical Evaluation of Low Contrast Defocus Curves, Low Light Photic Phenomena, and Dysphotopsia Profiles in Pseudophakic Patients","Inclusion Criteria:\n\n* Minimum 22 years of age\n* Bilateral pseudophakia, at least 3 months postoperative from IOL implantation, with one of the study IOL models in at least one eye.\n* Availability, willingness, and sufficient cognitive awareness to comply with examination procedures\n* Signed informed consent and HIPAA authorization or equivalent documentation necessary to comply with applicable privacy laws pertaining to medical treatment in the governing countries\n* Ability to understand and respond to a questionnaire in English\n\nExclusion Criteria:\n\n* Any clinically significant pupil abnormalities (non-reactive, fixed pupils, or abnormally shaped pupils.\n* Inability to focus or fixate for prolonged periods of time (e.g., due to strabismus, nystagmus, etc.)\n* Uncorrected distance visual acuity worse than 20\u002F25 in either eye\n* Prior corneal refractive surgery (LASIK, LASEK, RK, PRK, etc.) or intraocular surgery. Note: Prophylactic peripheral iridotomies and peripheral laser retinal repairs that, in the opinion of the investigator will not confound study outcomes are acceptable.\n* Posterior capsular opacification with grading worse than 1+\n* Ocular findings that may, in the opinion of the investigator, affect vision and\u002For contrast sensitivity","22 Years",{"count":45,"type":17},120,"1 Day","The goal of this clinical investigation is to evaluate visual acuity and contrast sensitivity in low lighting conditions using several different testing devices, and measure nighttime side effects of intraocular lens (IOL) implants after cataract surgery.\n\nResearchers will compare the results for three different types of IOLs to see how each lens contributes to overall visual function, patient experience and satisfaction.\n\nParticipants will:\n\n* Complete two different questionnaires about their current vision\n* Undergo visual testing using several different devices",[23,49,50,51,52],"Posterior Capsule Opacification","Visual Acuity","Visual Function","Contrast Sensitivity",[23,49,54,55,56,57,58,59,60,61,62,63,64,65,66],"Halometry","Manifold Vision Meter","PRVSQ","AIOLIS","TECNIS Eyhance IOL","TECNIS Symfony Optiblue IOL","TECNIS Odyssey IOL","Low Contrast","Defocus Curves","Low Light Photic Phenomena","Dysphotopsia Profiles","Pseudophakia","TECNIS 1-Piece","RECRUITING","2026-03-31",{"date":70,"type":29},"2026-04-06",{"date":72,"type":29},"2025-09-24",{"date":74,"type":17},"2026-08",{"name":76,"class":36},"Dr. Daniel H. Chang, MD",1,""]