[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"dysthymia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:dysthymia":52},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":32,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100571777",false,"NCT06724666","Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression","NEURO4C","Inclusion Criteria:\n\n* elevated symptoms of anxiety or depression\u002F internalizing problems (T score\\> 60) at intake (based on Youth self-report completed by adolescents)\n* primary diagnosis of an anxiety\u002Fdepressive disorder based on DSM-5 criteria according to ADIS-5-C\u002FP interview\n* age 13-17\n* able to read and understand Romanian language\n* Currently unmedicated or on stable and adequate doses of medication for at least 6 weeks before treatment onset\n* Internet access\n\nExclusion Criteria:\n\n* severe mental disorder (psychosis, severe depression, bipolar disorder, based on clinical interview)\n* any condition that interferes with the protocol implementation (e.g., physical illness or sensory impairment that interferes with behavioral tasks such as exposure, behavioral activation, unavailable for the next 3 months),\n* active suicidal ideation (assessed by child psychiatrist during clinical interview) in the last month\n* currently following CBT\u002F psychotherapy for anxiety\u002Fdepression, in the last 6 months\n* fMRI incompatible (based on safety questionnaire)\n* Being diagnosed with an intellectual disability, pervasive developmental disorder, an alcohol and\u002For substance dependence disorder, reading disabilities (based on clinical interview).\n* Current treatment with benzodiazepines","ALL","13 Years","17 Years",{"count":19,"type":20},198,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to test the efficacy of a transdiagnostic Internet-delivered interventions for Romanian adolescents with anxiety and\u002F or depression. The main questions it aims to answer are:\n\n* What is the clinical efficacy of the Internet-delivered intervention?\n* How accurate is the prediction model in predicting who will respond to treatment? Participants will undergo non-invasive fMRI to measure variability in brain signal as a proxy of the neural systems' adaptability before receiving the intervention, then they will be allocated either to the Internet-delivered intervention or control group.",[26,27,28,29,30,31],"Anxiety Disorders","Depressive Disorder","Social Anxiety Disorder","Major Depressive Disorder","Dysthymia","Generalized Anxiety Disorder",[33,34,35,36,37,38],"Internet-delivered intervention","transdiagnostic","adolescents","internalizing","anxiety","depression","RECRUITING","2025-04-02",{"date":42,"type":43},"2025-04-04","ACTUAL",{"date":45,"type":43},"2025-04-01",{"date":47,"type":20},"2026-06-30",{"name":49,"class":50},"Babes-Bolyai University","OTHER",2,""]