[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"emergency-laparotomies\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:emergency-laparotomies":77},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100635222",false,"NCT07549880","The Spotlight Study: Early Identification of Post-Surgical Infections Using Bedside Ultrasound.","Post-Laparotomy Fluid Monitoring With Point of Care Ultrasonography : Predicting Surgical Site Infection & Optimizing Patient Convalescence (SPOTLIGHT Study).","SPOTLIGHT","Inclusion Criteria:\n\n* Adults \\>18 years.\n* Undergoing emergency or elective laparotomy.\n* Primary or delayed primary wound closure (DPC).\n* Wound classification: clean, clean-contaminated, contaminated, or dirty.\n* Informed consent obtained.\n\nExclusion Criteria:\n\n* Laparoscopic surgery\n* Wounds healing by secondary intention.\n* Ongoing wound dehiscence treatment with Negative Pressure Wound Therapy (NPWT).\n* Non-Danish residents","ALL","18 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","Introduction:\n\nThe goal of this observational study is to learn whether point-of-care ultrasound (POCUS) can help detect early fluid build-up under the skin after open abdominal surgery (laparotomy) and whether these findings can predict surgical site infection. The study includes adults who recently had emergency or planned open abdominal surgery.\n\nHypothesis:\n\nThe main questions it aims to answer are:\n\n1. Does ultrasound identify subcutaneous fluid collections early after surgery?\n2. Do these fluid collections help predict which participants will develop a surgical site infection?\n\nIntervention:\n\nParticipants will:\n\n1. Have a superficial wound swab taken once at the start of the study (for research only).\n2. Receive three ultrasound scans of their surgical wound during days 1-3, 4-6, and 7-9 after surgery.\n3. Have their wound checked for redness, swelling, tenderness, or discharge before each scan.\n4. Be followed for 7 and 30 days after surgery (and up to 90 days if they have implanted mesh) to see whether an infection develops.\n\nUltrasound is non-invasive and safe. According to the protocol, \"no serious adverse effects are expected,\" though some participants may feel brief discomfort from pressure on a tender wound.\n\nThis study will help researchers understand whether routine bedside ultrasound can support earlier detection of wound infections and improve postoperative care in the future.",[26,27,28],"Surgical Site Infection (SSI)","Emergency Laparotomies","Point of Care Ultrasound (POCUS)",[30,31,32],"point of care ultrasound (POCUS)","surgical site infection (SSI)","Emergency laparotomies","RECRUITING","2026-04-17",{"date":36,"type":37},"2026-04-24","ACTUAL",{"date":39,"type":37},"2026-04-10",{"date":41,"type":20},"2027-08-30",{"name":43,"class":44},"Slagelse Hospital","OTHER",3,{"id":47,"slug":4,"hasResults":10,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100515275","NCT05989386","Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies","Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of Intraoperative Incision Wound in Preventing Surgical Site Infections in Emergency Laparotomies: A Randomized Controlled Trial","Inclusion Criteria:\n\n* • Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi\n\n  * The age of patients should be between 18-60 years old.\n\nExclusion Criteria:\n\n* Diabetic patients\n* Immune-suppressed patients\n* Patients taking steroids\n* Patients undergoing chemo-radiotherapy.\n* Pregnant females\n* Previous abdominal surgery within the last 30 days.\n* Presence of concurrent abdominal wall infections.\n* Trauma Laparotomies\n* Large Bowel perforations","60 Years",{"count":54,"type":20},200,[56,57],"PHASE2","PHASE3","The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are:\n\n* Incidence of SSI after intervention\n* Length of hospital stay\n\nParticipants will be randomly assigned to two groups receiving either of the two groups:\n\nGroup A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation.\n\nResearchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.",[60,61,62,27,63,64,65,66],"Surgical Site Infection","Surgical Wound","Surgical Incision","Laparotomies","Post Operative Wound Infection","Wound Infection","Seroma","2025-06-14",{"date":69,"type":37},"2025-06-18",{"date":71,"type":37},"2023-04-29",{"date":73,"type":20},"2025-12-29",{"name":75,"class":44},"Dow University of Health Sciences",1,""]