[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"endoscopic-video-assisted-nipple-sparing-mastectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:endoscopic-video-assisted-nipple-sparing-mastectomy":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100637699",false,"NCT07579117","Endoscopic Video-Assisted Nipple-Sparing Mastectomy","EVA - Endoscopic Video-Assisted Nipple-Sparing Mastectomy (E-NSM): A Pilot Study","EVA","Inclusion Criteria:\n\n* Female patients aged ≥18 years\n* Candidates for nipple-sparing mastectomy (NSM) with immediate reconstruction\n* Histologically confirmed invasive carcinoma cT1N0, or carriers of pathogenic germline mutations undergoing prophylactic mastectomy\n* Breast size I-III and absence of significant glandular ptosis\n* Signed informed consent\n\nExclusion Criteria:\n\n* Inflammatory breast cancer\n* Locally advanced clinical stage (cT2-T4 or N+)\n* Ductal carcinoma in situ (DCIS) without invasive component\n* Previous radiotherapy to the affected breast\n* Locoregional recurrence\n* Clinical conditions contraindicating prosthetic reconstruction\n* Indication for skin-sparing (SSM) or skin-reducing mastectomy (SRM)\n* Ongoing or completed neoadjuvant chemotherapy before surgery\n* Refusal or inability to sign informed consent\n* Inability to complete scheduled follow-up","FEMALE","18 Years",{"count":19,"type":20},10,"ESTIMATED","INTERVENTIONAL",[23],"NA","Endoscopic video-assisted nipple-sparing mastectomy (E-NSM) is an advancement in minimally invasive breast surgery designed to reduce surgical trauma and improve cosmetic outcomes while maintaining strict oncologic safety. The procedure will be carried out by a dedicated surgical team in which at least one operator holds certified laparoscopic surgical training issued by a recognized scientific society, ensuring appropriate technical expertise and adherence to surgical safety standards.",[26,27,28],"Endoscopic Video-assisted Nipple-sparing Mastectomy","Breast Surgery","Breast Cancer","RECRUITING","2026-05-28",{"date":32,"type":33},"2026-06-01","ACTUAL",{"date":35,"type":33},"2026-05-23",{"date":37,"type":20},"2027-07",{"name":39,"class":40},"European Institute of Oncology","OTHER",""]