Health Trials

Fasting Mimicking Diet

2

Review clinical trials related to Fasting Mimicking Diet. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

The purpose of this study is to learn the effects of fasting on cancer cells while you get maintenance treatment.

Participants needed: 66
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: VA Office of Research and DevelopmentUpdated: Nov 10, 2025Locations: 4
Eligibility criteria

18 years at the time of informed consent [+6]

Self-reported weight loss of > 10% in the 6 weeks prior to study entry [+7]

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Status: Not yet recruiting

Fasting-Mimicking Diet as an Adjunct to Neoadjuvant Chemotherapy for Hormone-Receptor-Positive Breast Cancer

This is a phase II, Single-Arm Clinical Study evaluating the efficacy and safety of a fasting-mimicking diet (FMD) combined with neoadjuvant chemotherapy in patients with ER-positive, HER2-negative breast cancer. Participants will be assigned to Intervention group: 4-day FMD cycles (827± 100kcal/day on Day 1, 637± 100kcal/day on Days 2-4) synchronized with T-EC chemotherapy. The primary endpoint is pathological complete response (pCR) rate. Secondary endpoints include metabolic changes, immune markers, quality of life, and safety (CTCAE v5.0). A total patients will be enrolled to detect a 15% pCR improvement (25% vs. 10%, α=0.05, power=80%).

Participants needed: 45
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Guangdong Provincial People's HospitalUpdated: Jul 22, 2025Locations: 1
Eligibility criteria

Histologically confirmed ER-positive , HER2-negative invasive ductal carcinoma m... [+6]

Prior history of any malignancy (including contralateral breast cancer) [+6]

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