Geriatrics

15

Review clinical trials related to Geriatrics. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Aging, Geriatric Syndromes and Clonal Hematopoiesis

In this study the investigators will incorporate a wide range of clinical variables associated with aging and cardiovascular disease to determine whether they are associated with mutation status independent of chronologic age. Clinically, aging can be operationalized using geriatric assessment, which entails a comprehensive multi-dimensional assessment of the health of an older adult, including measures of comorbidity, polypharmacy, functional status, cognition, depression, falls, social activities and social support. Given that aging is heterogeneous, geriatric assessment allows greater specificity for aging than chronological age alone.

Participants needed: 2,000
Trial details
Age: 50+Biological sex: AllType: ObservationalSponsor: Washington University School of MedicineUpdated: Jul 13, 2026Locations: 1
Eligibility criteria

At least 50 years of age. [+2]

Inability or unwillingness to complete health questionnaire (with the exception... [+7]

Status: Recruiting

Patient Experience of Older Adults Living Alone With Injuries

This study aims to explore the patient experiences of living alone older adults with injuries, and to examine the effects of a "Geriatric Trauma Care Program" in older adults with limb injuries who live alone. A three-year design will be used to reach the purposes of this study. The first stage of this study will use descriptive phenomenology to get patient experiences of living alone older adults with injuries. In the second stage of this study, a two-arm experimental design will be used.

Participants needed: 110
Trial details
Age: 65-74Biological sex: AllType: InterventionalSponsor: Kaohsiung Medical University Chung-Ho Memorial HospitalUpdated: May 27, 2026Locations: 2
Eligibility criteria

willing to join this study for 12 weeks [+6]

with an ISS greater than 16 (severe injuries) [+3]

Status: Recruiting

Manual Versus Autoflow Ventilation During Anesthesia Inductıon in Geriatric Patients

The objective of this study is to compare the effects of manual ventilation and AutoFlow ventilation, administered during the induction of general anesthesia, on cerebral (s-rSO₂) and peripheral (somatic) oxygenation (p-rSO₂) in geriatric patients.

Participants needed: 106
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: Ankara City Hospital BilkentUpdated: May 15, 2026Locations: 1
Eligibility criteria

Patients aged 65 years and older. [+3]

Patients with severe heart failure or severe pulmonary disease. [+4]

Status: Recruiting

Aging, Geriatric Syndromes and Clonal Hematopoiesis

In this study the investigators will incorporate a wide range of clinical variables associated with aging and cardiovascular disease to determine whether they are associated with mutation status independent of chronologic age. Clinically, aging can be operationalized using geriatric assessment, which entails a comprehensive multi-dimensional assessment of the health of an older adult, including measures of comorbidity, polypharmacy, functional status, cognition, depression, falls, social activities and social support. Given that aging is heterogeneous, geriatric assessment allows greater specificity for aging than chronological age alone.

Participants needed: 2,000
Trial details
Age: 50+Biological sex: AllType: ObservationalSponsor: Washington University School of MedicineUpdated: May 12, 2026Locations: 1
Eligibility criteria

At least 50 years of age. [+2]

Inability or unwillingness to complete health questionnaire (with the exception... [+7]

Status: Recruiting

Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions

The goal of this pilot clinical trial is to learn if providing a clinical decision framework for managing older adults chronic conditions during hospitalization to inpatient clinicians improves clinicians' ability to individualize chronic condition prescribing decisions for hospitalized older adults (65 and older). The main questions it aims to answer are: * Will the clinical decision framework lead to clinicians having greater confidence to individualize discharge prescribing? * Will clinicians using the framework discharge make fewer changes to hospitalized older adults with home diabetes and hypertension medications than they did prior to receiving the framework? * Will older adult patients of participating clinicians will report fewer gaps in understanding of medication changes after the clinician is exposed to the framework? Researchers will compare participating clinician survey responses and prescribing records from before and after an educational session presenting the clinical decision framework. Participants will be asked to * Attend a one-time educational session on the clinical decision framework * Complete 2 electronic surveys, one before and one following the educational session. * Agree for researchers to contact their patients, in order for patients to complete a one-time phone survey about changes made to home medications during hospitalization and quality of communication from the hospital team.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of PittsburghUpdated: Apr 14, 2026Locations: 1
Eligibility criteria

Attending clinicians who practice on the general medicine or hospital medicine s... [+1]

Anticipating leaving current clinical position within next 3 months [+5]

Status: Recruiting

Strength-based Tailored-Exercise Program at Home for Geriatric Patients

This study focuses on the "Strength-based Tailored-Exercise Program at Home (STEP@Home)" aimed at improving health outcomes for geriatric patients at risk of hospitalization-associated functional decline. It is a sequential mixed-method study that combines quantitative and qualitative approaches.

Participants needed: 256
Trial details
Age: 60+Biological sex: AllType: InterventionalSponsor: The University of Hong KongUpdated: Apr 6, 2026Locations: 1
Eligibility criteria

i) aged 60 or above [+5]

i) admitted with a disabling condition leading to significant functional loss su... [+3]

Status: Not yet recruiting

Evaluation of Efficacy of Coconut Oil Mouth Care for Non-autonomous Hospitalised Elderly People.

This is a prospective, longitudinal, randomised, open-label, multicentric, interventional, comparative superiority study. The main objective is to demonstrate the superiority of oral care with coconut oil on the oral status of elderly people hospitalised in geriatrics, versus oral care with glycerol sticks.

Participants needed: 94
Trial details
Age: 75+Biological sex: AllType: InterventionalSponsor: University Hospital, LimogesUpdated: Feb 12, 2026Locations: 2
Eligibility criteria

Patients aged 75 and over [+4]

Patients with a known allergy to coconut [+9]

Status: Not yet recruiting

Geriatrics in the Intensive Care Unit

Life expectancy is longer in populations of medium- and high-income countries. Older adults are an increasingly large population in intensive care units (ICUs). There are limited publications about the epidemiology, benefits, expenditure, and outcomes of elderly and very old critically ill patients. We are designing a study to characterize older adults admitted to the intensive care unit and determine factors associated with adverse outcomes. The discharge registry of the ICU of a third-level hospital was reviewed. Records from January to December 2024 were reviewed. Three age groups were selected for comparison: A. \<65 years; B. 65-79 years; C. 80 years and above. The outcomes to compare will be: mortality, need for invasive mechanical ventilation, ICU length of stay, and duration of mechanical ventilation.

Participants needed: 1,000
Trial details
Age: 18-120Biological sex: AllType: ObservationalSponsor: Hospital Departamental de VillavicencioUpdated: Feb 9, 2026Locations: 1
Eligibility criteria

Registry of adults older than 18 years, discharged from the critical care unit.

None.

Status: Recruiting

Carotid Artery Corrected Flow Time and Inferior Vena Cava Collapsibility Index for Prediction of Hypotension After Induction of General Anesthesia in Geriatric Patients Undergoing Elective Surgery

In this observational study, we will assess cFT by Carotid ultrasound and IVC collapsibility index for prediction of hypotension after induction of general anesthesia in geriatric patients undergoing elective surgery.

Participants needed: 189
Trial details
Age: 65+Biological sex: AllType: ObservationalSponsor: Tanta UniversityUpdated: Jul 1, 2025Locations: 1
Eligibility criteria

American Society of Anaesthesiologists Physical Status I to Ⅱ [+2]

• patients who refused to participate in the study [+7]

Status: Recruiting

Perturbation-Based Treadmill Training to Prevent Unrecovered Falls in Geriatric Patients

The goal of this clinical trial is to determine the effectiveness of perturbation-based balance training (PBT) in preventing unrecovered falls among geriatric patients aged ≥70 years with a prospective fall risk of ≥40%. The study will also assess the safety and feasibility of PBT. The main research questions are: A total of 396 participants will receive 9 training sessions of either PBT or conventional treadmill training and will attend an assessment before and after the intervention, as well as 6 and 12 months follow up. Falls will be documented throughout the entire study period using calendars, telephone interviews, and proxy information. The primary outcome, unrecovered falls, will be recorded after the end of the intervention until 12 months follow up.

Participants needed: 396
Trial details
Age: 70+Biological sex: AllType: InterventionalSponsor: University of OldenburgUpdated: May 14, 2025Locations: 3
Eligibility criteria

≥ 70 years [+4]

MoCA score < 10 pts (or MMSE < 17 pts) [+10]

Status: Recruiting

Pericapsular Nerve Group and Lumbar Erector Spinae Plane Blocks for Geriatrics Undergoing Total Hip Arthroplasty

This study will be conducted to evaluate the effect of pericapsular nerve group and erector spinae plane block as adjuvants to general anesthesia in geriatrics undergoing total hip arthroplasty.

Participants needed: 120
Trial details
Age: 75+Biological sex: AllType: InterventionalSponsor: Tanta UniversityUpdated: Apr 1, 2025Locations: 1
Eligibility criteria

Aged >75 years. [+3]

Patient refusal. [+5]

Status: Recruiting

Understanding the Preferences and Views of Older Adults on the Use of Geriatric and Objective Functional Assessments for Cancer Treatment Planning.

This Interventional clinical study aims to explore how receiving information about their health and physical abilities affects the treatment decisions of older adults. The study will look at whether sharing detailed assessments of their health and functional status helps older adults better understand their condition and make informed decisions about their care. The main question it aims to answer is if providing this information changes the treatment priorities of older adults, helping them focus on what matters most to them in their medical care.

Participants needed: 100
Trial details
Age: 65+Biological sex: AllType: InterventionalSponsor: Fox Chase Cancer CenterUpdated: Feb 27, 2025Locations: 1
Eligibility criteria

Age ≥ 65 [+2]

Patients will be excluded if they [+4]

Status: Recruiting

RISK FACTOR ANALYSIS OF CHEWING AND SWALLOWING PERFORMANCE IN GERIATRICS

Various structural and functional problems in neural, sensory and perceptual, cardiovascular, pulmonary, gastrointestinal, endocrine, and musculoskeletal systems occur in geriatrics not associated with a specific disease. One of the problems observed in geriatrics is chewing and swallowing disorders. Failure to detect changes in chewing and swallowing performance in elderly individuals at an early stage may lead to chewing and swallowing disorders and serious complications in later stages. Therefore, it is necessary to comprehensively and systematically address the possible factors affecting chewing and swallowing performance in geriatric individuals. The first aim of the study is to analyze the factors affecting chewing and swallowing performance in geriatric individuals within the scope of the International Classification of Functioning, Disability, and Health (ICF). The second aim of the study is to create a dysphagia risk prediction model for geriatric individuals based on the results of the analyses to be conducted. In the study, the dependent variables, chewing performance, will be evaluated with the Chewing and Swallowing Test of Solids, and swallowing performance will be assessed with the Repetitive Saliva Swallowing Test and Dysphagia Limit. Independent variables affecting chewing and swallowing performance have been considered within the scope of the ICF, and all possible factors determined for both geriatrics and swallowing have been listed, and the evaluation parameters and assessment tools have been decided. The evaluation parameters have been categorized under ICF headings such as personal factors, body structures, body functions, activity and participation, and environmental factors, and the evaluations to be conducted have been divided into two groups: geriatric and physiotherapy evaluations. The geriatric evaluations are part of routine geriatric assessment and do not include any specific evaluation for the study. Physiotherapy evaluations will be applied in a certain order to use time efficiently and will take approximately 35-45 minutes. Through geriatric and physiotherapy evaluations, a holistic assessment of participants within the scope of ICF will be ensured.

Participants needed: 240
Trial details
Age: 65-120Biological sex: AllType: ObservationalSponsor: Atılım UniversityUpdated: Jul 9, 2024Locations: 1Duration: 1 Day
Eligibility criteria

being voluntary to participation, [+3]

Having a problem that prevents communication and/or following simple instruction...

Status: Recruiting

Comparative Effects of Sensory Integration Therapy and Balance Board Training in Community Dwelling Older Adults

Balance plays a significant role in stability and walking and it's essential for improving the quality of life and functional autonomy while reducing the risk of falling. This research intends to shed light on the advantages of sensory integration therapy and balance board training because it is important to addressing the issues related to ageing and their possible effects.

Participants needed: 58
Trial details
Age: 60-75Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Jun 26, 2024Locations: 2
Eligibility criteria

Should be living independently (FIM 108-126). [+3]

Individuals with recent cardiac or neurological changes in medical status. [+3]

Status: Recruiting

Comparative Effects of Modified Otago and Frenkel's Exercises in Geriatric Population

The goal of this randomized clinical trial is to compare the effects of modified Otago and Frenkel's exercises on balance, motor function, fear of fall and quality of life in the geriatric population. The main questions it aims to answer are: * How modified Otago and Frenkel's exercises affect balance, motor function, fear of fall and quality of life in the geriatric population? * Is there any difference between the effects of these two exercises? Researchers will compare the effects of modified Otago and Frenkel's exercises to see which kind of exercise has superior effects on the mentioned outcomes. Participants will be randomly divided into two groups who will perform their respective exercises for 45 minutes 3 days a week for 8 weeks. Outcomes will be evaluated at the baseline, 4th week and 8th week.

Participants needed: 44
Trial details
Age: 65-80Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Jun 14, 2024Locations: 1
Eligibility criteria

Community-dwelling adults of both genders who have experienced a fall at least o... [+2]

Unable to walk independently. [+5]