Hearing Loss Adult Onset

7

Review clinical trials related to Hearing Loss Adult Onset. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Cochlear Implant Speech in Noise Processing

The study will help us in understanding the neural mechanisms by which listeners with a cochlear implant detect speech in noisy environments.

Participants needed: 150
Trial details
Age: 18-99Biological sex: AllType: InterventionalSponsor: Craig D. Workman, PhDUpdated: May 14, 2026Locations: 1
Eligibility criteria

Between 18 and 99 years of age. [+8]

Medical history includes seizure disorder, head injury, neurologic, metabolic, c... [+3]

Status: Not yet recruiting

AI-assisted Diagnosis, Triage and Assessment of Hearing Loss and Tinnitus

Hearing loss affects approximately 11 million people in the UK, while tinnitus impacts around 7 million. Both conditions can significantly reduce quality of life and are linked to poorer mental health and employment challenges. Each year, tinnitus alone accounts for more than one million GP appointments, and patients referred to hospital ear, nose and throat (ENT) services often face long delays, sometimes exceeding a year, before their first assessment. To address this demand, the Royal Cornwall Hospitals NHS Trust has developed a virtual ENT clinic. Patients undergo a validated hearing test in person and complete online questionnaires. Clinicians then review these data to determine next steps, which may include discharge with advice, referral for imaging, or a face-to-face consultation. Initial trials demonstrated that the majority of patients could be managed virtually, substantially reducing waiting times. However, clinicians must still review every case, limiting capacity for patients who require direct care. This project builds on the virtual clinic by introducing artificial intelligence (AI) to support the assessment process. Using explainable AI methods, the system will be trained to replicate clinician-level decision-making while providing transparent reasoning for its recommendations. The study will evaluate how closely AI-generated outcomes align with clinician assessments, with all cases continuing to receive a clinician's final review. Clinicians will not be aware of the recommendations produced by the AI tool, but the study aims to measure how concordant AI recommendations are with clinician assessments. If the AI tool's clinical recommendations closely align with clinician recommendations (the gold standard for care), the AI tool could be introduced as a clinical recommendation assistant tool, streamlining the triage and management of hearing loss and tinnitus, enabling clinicians to focus on complex cases, accelerating access to care, and improving efficiency.

Participants needed: 1,500
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Royal Cornwall Hospitals TrustUpdated: May 14, 2026Locations: 1Duration: 1 Year
Eligibility criteria

Patients assessed in the RCHT virtual hearing loss and tinnitus clinic. [+2]

Individuals under 18 years of age. [+3]

Status: Recruiting

Use of Airpod Pros as Assistive Technology

The goal of this study is to investigate the suitability and effectiveness of the AirPod Pro 2nd and 3rd generation (AP) as hearing assistive technology for individuals with mild-to-moderate hearing loss when listening in noisy environments. Researchers will compare four types of assistive technology: hearing aids (HAs), AP, dedicated wireless remote microphones, and Smartphone wireless remote microphone. The main questions it aims to answer are: * Which assistive technology provides the greatest benefit for speech recognition in noisy environments? * How do these devices impact listening effort, as measured by reaction time in a dual-task activity and changes in pupil size? * What are participants' preferences for each device based on how easy it is to understand speech and their overall satisfaction? Participants will visit the lab for a single 3-hour session. They will listen to sentences using each device and repeat what they hear. During this task, their reaction times for the secondary task and changes in pupil size will be measured.

Participants needed: 24
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: The University of Texas at DallasUpdated: May 11, 2026Locations: 1
Eligibility criteria

Adults aged 18 to 60 years. [+3]

Normal hearing. [+4]

Status: Not yet recruiting

Hearing Loss and Brain Health Study

Hearing loss is a prevalent and modifiable risk factor for cognitive decline and dementia in older adults, yet access to hearing care remains limited. Over-the-counter (OTC) hearing aids represent a promising and scalable strategy to expand access, particularly for individuals at elevated risk for dementia who may benefit most from earlier intervention. This pilot study aims to evaluate the feasibility and acceptability of OTC hearing aid use among older adults. Participants aged ≥50 years will undergo standardized hearing screening to identify bilateral, mild-to-moderate hearing loss. Eligible participants will be randomized to one of two sequences: (1) immediate intervention: 3-mo using OTC hearing aids or (2) waitlist control: 3-mo without devices followed by OTC hearing aid use after 3 months. Feasibility outcomes include study enrollment and retention, protocol adherence, and average daily device use determined by data-logging. Acceptability outcomes will be assessed using the International Outcome Inventory for Hearing Aids (IOI-HA), device satisfaction ratings, and participant intention to continue hearing-aid use. Hearing outcomes include validated questionnaires on hearing and listening efforts. Findings will inform the design of larger trials aimed at improving access to hearing care and promoting cognitive health.

Participants needed: 40
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: University of Southern CaliforniaUpdated: May 8, 2026Locations: 1
Eligibility criteria

Age >= 50 years [+6]

Clinical diagnosis of dementia [+7]

Status: Recruiting

Hearing Healthcare Assessment in Rural Communities

Adult hearing loss in is the third most common chronic health condition in the United States. Adults living in rural areas face a higher risk of experiencing hearing loss, and more difficulty receiving testing and treatment than adults in urban settings. The goal of this clinical trial is to develop and test a community-based hearing healthcare patient navigation program in rural Kentucky. The main question this study aims to answer is: -Can the number of rural adults receiving diagnostic hearing tests be increased?

Participants needed: 500
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Matthew Bush, MDUpdated: May 6, 2026Locations: 9
Eligibility criteria

Age 18 years or older [+2]

Status: Recruiting

Hearing Aid Benefit in Real-World Noisy Environments

Researchers are doing this study to understand why hearing aids often work well in controlled laboratory settings but don't provide the same level of benefit in everyday noisy environments. The questions they hope to answer are: * What factors contribute to hearing aid benefit in noisy environments * What factors limit hearing aid benefit * How do real-world factors interact with common hearing aid settings Participants will complete: * Hearing and listening tests * Memory and attention assessment * Surveys on their Smartphone

Participants needed: 45
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Wisconsin, MadisonUpdated: Feb 24, 2026Locations: 1
Eligibility criteria

Over 18 years old [+2]

Under 18 years old [+4]

Status: Recruiting

Evaluation of Performances, Clinical Benefits and Safety of the 'Audiocap' Connected Hearing Rehabilitation Device for Improving Audibility in Hearing-impaired People in the Context of CE Marking - AUDIOCAP-2

The goal of this clinical trial is the evaluation of performances, clinical benefits and safety of the 'Audiocap' connected hearing rehabilitation device for improving audibility in hearing-impaired people. The main question it aims to answer is to demonstrate, after one month's use of the Audiocap connected hearing aid, that the audiological gain for the patient is better than with a placebo hearing aid. Placebo hearing aid is a Audiocap connected hearing aid with a 'NONE' setting (flat frequency response for the patient (equivalent to not wearing hearing aid). Participants will be first-time hearing aid users, eligible for hearing aid fitting, and adults according to French legislation (18 years and older).

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Archean TechnologiesUpdated: Nov 26, 2025Locations: 4
Eligibility criteria

Subjects presenting one or more of the following criteria: a.Subject with mild t... [+2]

Subject deprived of his/her liberty by a judicial or administrative decision [+16]