[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"heart-injuries\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:heart-injuries":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100585127",false,"NCT06898320","Cardiac Injury Due to Anthracycline in Paediatric Oncological Patients","Prediction of Cardiac Injury Due to Anthracycline Chemotherapy in Paediatric Oncological Patients Using Advanced Echocardiography and Circulating Biomarkers.","Inclusion Criteria:\n\n* Paediatric oncological patients 0-18 years\n* Planned start of anthracycline therapy\n* Normal left ventricular systolic function according to International Guidelines before the treatment with AC\n\nExclusion Criteria:\n\n* Previous anthracycline treatment, bone marrow transplantation or chest radiation\n* Pre-anthracycline treatment echocardiographic evidence of:\n* More than mild pericardial effusion\n* More than mild mitral regurgitation\n* Poor echocardiographic acoustic window","ALL","0 Years","18 Years",{"count":19,"type":20},22,"ESTIMATED","OBSERVATIONAL","The study investigates the role of echocardiography and of serum biomarkers (NT-proBNP, cardiac Troponin-I) in predicting cardiac injury in a cohort of paediatric oncological patients treated with Anthracycline chemotherapy.",[24,25],"Heart Injuries","Anthracycline",[27,28,29,30],"Cardiac injury","Anthracycline chemotherapy","echocardiography","Circulating biomarkers","RECRUITING","2025-05-06",{"date":34,"type":35},"2025-05-09","ACTUAL",{"date":37,"type":35},"2023-07-21",{"date":39,"type":20},"2033-07-21",{"name":41,"class":42},"IRCCS Burlo Garofolo","OTHER",""]