Hepatic Fibrosis

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Review clinical trials related to Hepatic Fibrosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Screening for Advanced Liver Fibrosis Using Non-invasive Tests in Primary Care

Liver fibrosis screening is possible at the asymptomatic stage through a healthcare management strategy currently recommended for patients with risk factors for chronic liver disease. It is based on a sequential strategy involving a 1st-line test, fibrosis score calculation (FIB-4). Given this opportunity to identify advanced fibrosis in asymptomatic patients, the project aims to set up this screening program in the Grenoble area with Biogroup Laboratories, in collaboration with the Hepato-gastroenterology department (HGE) of Grenoble University Hospital. The aim of this study is to evaluate the success of sequential screening using FIB-4, followed by a specialized fibrosis test for the diagnosis of advanced hepatic fibrosis

Participants needed: 500
Trial details
Age: 18-70Biological sex: AllType: ObservationalSponsor: University Hospital, GrenobleUpdated: May 20, 2026Locations: 1
Eligibility criteria

Patients between 18 and 70 years of age [+2]

Prescription triggering FIB-4 emanate from a hepatogastroenterologist or oncolog... [+3]

Status: Recruiting

Study of the Efficacy and Safety of Nicotinamide in Patients With Liver Fibrosis (NICOFIB)

The objective of this clinical trial, a pilot study, is to assess the impact of nicotinamide (NAM) on individuals with hepatic fibrosis. The main question it aims to answer is: \- To determine if the treatment with NAM is able to arrest, or even reduce, the hepatic fibrosis. In addition, we also want to study the effect of NAM on: * General parameters (weight, HOMA-IR, etc). * Adiposity distribution (liver and body). * Systemic inflammation. * Thermogenic capacity of adipose tissue. * Microbiota composition. Researchers will compare NAM to a placebo, to see if NAM can arrest or revert hepatic fibrosis and its associated effects. Participants will take either NAM or placebo. The dosage will be 1.2g/m2 NAM per day, for one year.

Participants needed: 30
Trial details
Phase: Phase 2Age: 18-85Biological sex: AllType: InterventionalSponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauUpdated: Nov 18, 2025Locations: 1
Eligibility criteria

Patients aged between 18 and 85 years. [+3]

Patients with any medical condition or illness that, in the opinion of the inves... [+29]

Status: Not yet recruiting

Efficacy of Sodium Glucose Cotransporter 2 Inhibitors on Non-Alcoholic Fatty Liver Disease

evaluate the effectiveness of sodium-glucose cotransporter-2 (SGLT.2) inhibitors in improving hepatic steatosis and hepatic fibrosis using imaging biomarkers and histopathology in patients with non-alcoholic fatty liver disease

Participants needed: 100
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Assiut UniversityUpdated: Dec 18, 2024
Eligibility criteria

age >18 years [+1]

alcohol drinker [+2]

Status: Not yet recruiting

Correlation Between Serum Adiponectin And Resistin Levels And Degree of Hepatic Fibrosis in MASlD With type2 Diabetes Mellitus

Metabolic dysfunction asociated steatotic liver disease prevalence is 25%world wide diabetic patients have a risk for MASLD then have hepatic fibrosis so we study correlation Between Serum Adiponectin And Resistin Levels And Degree of Hepatic fibrosis In Metabolic dysfunction asociated steatotic liver disease in patients with type2 Diabetes Mellitus

Participants needed: 80
Trial details
Age: 30-65Biological sex: AllType: ObservationalSponsor: Sohag UniversityUpdated: Dec 4, 2024
Eligibility criteria

patients of both sex who have type2 Diabetes Mellitus for less than five years