[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"homocystinuria-due-to-cbs-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:homocystinuria-due-to-cbs-deficiency":38},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":32,"leadSponsor":34,"locationsCount":37},"100285674",false,"NCT02998710","Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)","A Multicenter, Observational, Prospective, Natural History Study of Homocystinuria Due to Cystathionine Beta-synthase Deficiency in Pediatric and Adult Patients (ACAPPELLA)","Inclusion Criteria:\n\n* Patients who are clinically diagnosed with homocystinuria\n* Male\u002Ffemale patients aged 1 to 65 years\n* Patients who consented and\u002For assented\n* Patients who are willing and able to comply with all study-related procedures.\n\nExclusion Criteria:\n\n* Medically significant postnatal complications or congenital anomalies that are not associated with homocystinuria\n* Received any experimental therapy for homocystinuria during the 6 months prior to enrollment or expected to receive any such therapy during duration of the study","ALL","1 Year","65 Years",{"count":19,"type":20},150,"ESTIMATED","OBSERVATIONAL","The purpose of the study is to characterize the clinical course of homocystinuria in pediatric and adult patients aged 1 to 65 years under current clinical management practices",[24],"Homocystinuria Due to CBS Deficiency","RECRUITING","2024-11-19",{"date":28,"type":29},"2024-11-22","ACTUAL",{"date":31,"type":29},"2017-01",{"date":33,"type":20},"2026-08",{"name":35,"class":36},"Travere Therapeutics, Inc.","INDUSTRY",11,""]