[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypermobility-type-ehlers-danlos-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypermobility-type-ehlers-danlos-syndrome":53},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":5},"100639329",false,"NCT07626957","Hamstring Strengthening in Hypermobile Conditions","Effects and Feasibility of Eccentric Hamstring Strengthening in Hypermobility Spectrum Disorders and Hypermobile Ehlers-Danlos Syndrome","Inclusion Criteria:\n\n* Reported diagnosis of HSD or hEDS by a physician\n* Meet the 2017 International Diagnostic Criteria for HSD and hEDS\n* Clearance to participant in exercise participation, determined using the Get Active Questionnaire\n\nExclusion Criteria:\n\n* Other acquired or hereditary connective tissue disorder (i.e., rheumatoid arthritis, Marfan syndrome, etc.)\n* Currently experiencing daily knee pain\n* Prior knee injury or surgery\n* Intra-articular knee injection in the last 12 months\n* Currently pregnant","FEMALE","18 Years","55 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to determine how strengthening the hamstring muscles affects the knee joint in people living with hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS). The main questions it aims to answer are:\n\n* Does hamstring strengthening reduce the looseness of the knee joint in HSD\u002FhEDS?\n* Does hamstring strengthening improve clinical outcomes like pain in people living with HSD\u002FhEDS?\n\nParticipants will:\n\n* Attend two exercise classes per week for 12 weeks.\n* Visit the laboratory every 4-6 weeks for testing.",[26,27,28,29],"Hypermobile EDS (hEDS)","Hypermobile Ehlers-Danlos Syndrome","Hypermobile Spectrum Disorder","Hypermobility Type Ehlers-Danlos Syndrome",[31,32,33,34,35,36,37,27,38,39,40],"Exercise","Female","Knee","Joint Laxity","Hypermobility","Joint Stiffness","Ehlers-Danlos Syndrome","Hypermobility Spectrum Disorders","strengthening","eccentric","NOT_YET_RECRUITING","2026-05-29",{"date":44,"type":45},"2026-06-04","ACTUAL",{"date":47,"type":20},"2026-06-01",{"date":49,"type":20},"2027-08-01",{"name":51,"class":52},"University of Calgary","OTHER",""]