Health Trials

Hypertonia Muscle

2

Review clinical trials related to Hypertonia Muscle. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

The researchers are investigating if the Self-Supporting Nasopharyngeal Airway (ssNPA) device can be used in the treatment of obstructive sleep apnea in children with Hypotonic Upper Airway Obstruction (HUAO).

Participants needed: 40
Trial details
Age: 3-21Biological sex: AllType: InterventionalSponsor: University of MichiganUpdated: Mar 12, 2026Locations: 1
Eligibility criteria

Children with Hypotonic Upper Airway Obstruction (HUAO): This includes those who... [+4]

AHI ≤10 on polysomnogram (PSG) without hypoxemia or AHI<5 with hypoxemia. [+9]

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Status: Recruiting

Longitudinal Study of Neurogenetic Disorders

The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medical problems and any treatment. The investigators will maintain an ongoing database of medical data that is otherwise being collected for routine medical care. The investigators will also collect data prospectively in the form of questionnaires, neuropsychological assessments, motor assessments, and electroencephalography to examine the landscape of deleterious variants in these genes.

Participants needed: 1,000
Trial details
Biological sex: AllType: ObservationalSponsor: Columbia UniversityUpdated: Oct 27, 2025Locations: 1Duration: 5 Years
Eligibility criteria

Individuals must have had whole genome/exome sequencing and have a confirmed var...

Subjects who cannot provide genetic confirmation of a predicted deleterious vari...

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