[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypoxic-events\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypoxic-events":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100639705",false,"NCT07621367","Gut Oxygen Therapy for Ischemic-Hypoxic Bowel Disease","Efficacy and Safety of Gut Oxygen Therapy for Ischemic-Hypoxic Bowel Disease: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study","Inclusion Criteria:\n\n* Clinical diagnosis of intestinal ischemia and hypoxia-related diseases caused by conditions such as ischemic bowel disease, heart failure, etc., presenting with recurrent or persistent abdominal pain and\u002For distension, and difficulty in defecation. Examples include: heart failure-related defecation difficulty, severe malnutrition combined with defecation difficulty, acute ischemic bowel disease, and chronic ischemic bowel disease.\n* At least able to perform bedside activities and able to defecate in conventional positions (sitting or squatting).\n* Age ≥18 years, and able to voluntarily sign informed consent.\n\nExclusion Criteria:\n\n* Acute intestinal emergencies such as acute intestinal obstruction, intestinal perforation, or active massive gastrointestinal bleeding.\n* Intestinal fistula.\n* History of abdominal surgery within the recent past (\\\u003C1 month).\n* Severe uncontrolled arrhythmia or respiratory failure.\n* Cardiac function Class IV (NYHA Class IV).\n* Patients with abnormal visceral pressure sensitivity.\n* Inability to cooperate with study assessments.\n* Other conditions that, in the opinion of the investigator, make the subject unsuitable for inclusion.","ALL","18 Years",{"count":18,"type":19},90,"ESTIMATED","INTERVENTIONAL",[22],"NA","This multicenter, randomized, double-blind, placebo-controlled clinical trial aimed to investigate the efficacy and safety of gut oxygen therapy in the treatment of ischemic-hypoxic bowel disease using deep intestinal catheterization as a targeted route for gut oxygen delivery.",[25,26],"Ischemic Bowel Disease","Hypoxic Events",[28,29,30,31,32],"ischemic bowel disease","heart failure","abdominal pain","abdominal distension","difficult defecation","RECRUITING","2026-06-01",{"date":36,"type":37},"2026-06-02","ACTUAL",{"date":39,"type":19},"2026-05-28",{"date":41,"type":19},"2031-05-19",{"name":43,"class":44},"The Second Hospital of Nanjing Medical University","OTHER",""]