[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"in-stent-coronary-artery-restenosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:in-stent-coronary-artery-restenosis":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100623007",false,"NCT07391033","The PICCOLETO XI A-PREP Study","Impact of Lesion PREParation With Modifying Balloons During Drug-coated Balloon (DCB) Angioplasty for In-stent Restenosis (ISR) - PICCOLETO XI A-PREP Study","PICCOLETO-XI","Inclusion Criteria:\n\n* Adult patients ≥18 years of age\n* Patients who underwent DCB angioplasty for in-stent restenosis\n\nExclusion Criteria:\n\n\\- Lack of clinical outcome assessment","ALL","18 Years",{"count":19,"type":20},500,"ESTIMATED","OBSERVATIONAL","To compare the angiographic and clinical outcomes of aggressive versus standard balloon preparation during drug-coated balloon (DCB) angioplasty for in-stent restenosis (ISR). The study will evaluate whether more aggressive lesion preparation with cutting\u002Fscoring\u002FOPN balloons improves outcomes compared to standard preparation with semi-compliant or non-compliant balloons.",[24,25],"In-Stent Coronary Artery Restenosis","Coronary Artery Disease",[27,28,29,30,31,32],"Drug-Coated Balloon","In-Stent Restenosis","Lesion Preparation","Cutting Balloon","Scoring Balloon","Percutaneous Coronary Intervention","NOT_YET_RECRUITING","2026-01-29",{"date":36,"type":37},"2026-02-05","ACTUAL",{"date":39,"type":20},"2026-06-01",{"date":41,"type":20},"2028-06-01",{"name":43,"class":44},"Fondazione Ricerca e Innovazione Cardiovascolare ETS","OTHER",""]