[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"indeterminate-pulmonary-nodules\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:indeterminate-pulmonary-nodules":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100468116",false,"NCT05375591","AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer","Artificial Intelligence & Radiomics for Stratification Of Lung Nodules After Radically Treated Cancer (AI-SONAR)","AI-SONAR","Inclusion Criteria:\n\n* Confirmed history of previous radically or curative-intent treated solid organ cancer within 10 years of new index CT thoracic scan demonstrating a new pulmonary nodule and either of the following:\n\n  * Biopsy confirming previous malignancy with MDT consensus and successful cancer resolution\u002Fremission following anti-cancer treatment on interval imaging or blood assay analysis\n  * Where biopsy was not possible\u002Fconfirmed for previous malignancy, MDT consensus outcome confirming cancer (+\u002F- calculated Herder score \\>80% if applicable) and decision to treat as malignancy with subsequent resolution\u002Fremission following anti-cancer treatment on interval imaging or blood assay analysis\n* Radical treatment for previous cancer defined as either of the following:\n\n  * Surgical resection\n  * Radical radiotherapy or stereotactic beam radiotherapy\n  * Radical chemotherapy\n  * Radical chemo-radiotherapy\n  * Multi-modality treatment with any of the above\n* New pulmonary nodule ground truth known\n\n  * Scan data showing 2-year stability (based on diameter or volumetry) or resolution in cases of benign disease\n  * Scan data showing progressive nodule enlargement or increase in nodule number on interval imaging with MDT consensus (+\u002F- PET with Herder score \\>80% if applicable) determining metastatic disease or new primary malignancy\n  * Biopsy sampling confirming benign disease or malignancy and in cases of malignancy, metastasis or new primary lung cancer\n* CT scan slice thickness ≤ 2.5mm\n* Nodule size ≥ 5mm\n\nExclusion Criteria:\n\n* CT Imaging \\> 10 years old\n* Non-solid haematological malignancies including leukaemia\n* Cases of radically treated primary cancer disease with early oligometastatic recurrence treated radically","ALL","18 Years",{"count":19,"type":20},1000,"ESTIMATED","OBSERVATIONAL","This study will assess the utility of radiomics and artificial intelligence approaches to new lung nodules in patients who have undergone radical treatment for a previous cancer.",[24,25,26,27],"Indeterminate Pulmonary Nodules","Lung Metastases","Second Primary Cancer","Lung Cancer","RECRUITING","2022-05-17",{"date":31,"type":32},"2022-05-24","ACTUAL",{"date":34,"type":32},"2021-10-13",{"date":36,"type":20},"2026-11-01",{"name":38,"class":39},"Royal Marsden NHS Foundation Trust","OTHER",2,""]