[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"injectable-platelet-rich-fibrin\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:injectable-platelet-rich-fibrin":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100539319",false,"NCT06302296","Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement","Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement During Leveling and Alignment Stage Study Description","Inclusion Criteria:\n\n* The patient's age (18-26). Severe or very severe irregularity of the upper incisors greater than (7 mm) according to Little's index, so it is recommended to extract the upper first premolar.\n\n  * Class I or Class II malocclusion, first model according to Angle, with skeletal class I or II and a normal or mild vertical growth pattern.\n  * All permanent upper teeth, up to the first molar, are present, with the possibility of attaching brackets to all teeth in a correct position.\n  * The patient has good oral health.\n\nExclusion Criteria:\n\n* • The presence of any systemic disease that affects orthodontic dental movement.\n\n  * Severe malalignment of one of the teeth (palatal quadrant, ectopic canine, ectopic premolar).\n  * The patient has undergone previous orthodontic treatment.\n  * The patient is subject to any drug treatment that may affect orthodontic dental movement (cortisone, non-steroidal anti-inflammatory drugs).\n  * The patient has poor oral health.\n  * Commitment to periodic follow-up appointments.","ALL","18 Years","26 Years",{"count":19,"type":20},14,"ESTIMATED","INTERVENTIONAL",[23],"NA","One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which makes the results difficult to generalize.",[26,27],"Tooth Mobility","Injectable Platelet-rich Fibrin","RECRUITING","2025-09-09",{"date":31,"type":32},"2025-09-15","ACTUAL",{"date":34,"type":20},"2025-12-20",{"date":36,"type":20},"2026-07-15",{"name":38,"class":39},"Hama University","OTHER",""]