[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"iol\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:iol":38},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":5},"100482395",false,"NCT05561478","Comparison of Visual Outcomes After Implantation of the Synthesis Plus and Synthesis Plus Toric","DETPLUST","Inclusion Criteria:\n\n* Patient older than 50 years old\n* Patient requiring bilateral cataract surgery\n* Regular corneal astigmatism \\>0.5D measured by MS-39 (SimK keratometry and regularity determined by the topography) for patients implanted with SYNTHESIS PLUS TORIC or Regular corneal astigmatism lower or equal to 0.5 D dioptres by MS-39 (SimK keratometry and regularity determined by the topography) for patients implanted with SYNTHESIS PLUS.\n* Expected postoperative astigmatism ≤ 0.75D diopter\n* Corneal astigmatism ≤4D\n* IOL spherical equivalent power requested between 15D and 25D\n* Signed informed consent\n* Availability, willingness and sufficient cognitive awareness to comply with examination procedures\n\nNon inclusion Criteria:\n\n* Patients with a potential postoperative visual acuity of less than 5\u002F10, in particular due to degenerative visual disorders, poor retinal function or a damaged cornea.\n* Amblyopia with a visual acuity potential of less than 5\u002F10\n* IOL power needed outside the spherical equivalent diopter range: 15 to 25D\n* Difficulty for cooperation (distance from their home, general health condition)\n* Acute or chronic disease or illness that would increase risk or confound study results (e.g. diabetes mellitus (with retinopathy), immunocompromised, glaucoma etc…)\n* Irregular astigmatism\n* Subject with postoperative astigmatism, expected \\> 0.75 D.\n* Any ocular comorbidity\n* History of ocular trauma or prior ocular surgery including refractive procedures\n* Capsule or zonular abnormalities that may affect postoperative centration or tilt of the lens (e.g. pseudoexfoliation syndrome, chronic Uveitis, Marfan's syndrome)\n* Patients with chronic uveitis\n* Pupil abnormalitis (non-reactive, tonic pupils, abnormally shaped pupils or pupils that do not dilate under mesopic\u002Fscotopic conditions, diameter (pupil\\>4mm or \\\u003C2.5 mm in photopic conditions))\n* Narrow anterior chambers (ACD ≤ 2.5 mm)\n* Any corneal pathology potentially affecting the topography (eg. Keratoconus),\n* Monophthalma patients\n* Phacodonesis\n\nExclusion criteria:\n\n* Complicated surgery\n* Inability to place the intraocular lens safely at the location planned\n* Subjects with zonular laxity\n* Postoperative endophthalmitis","ALL","50 Years",{"count":18,"type":19},72,"ESTIMATED","OBSERVATIONAL","Prospective controlled monocentric study to determine the non-inferiority of the distance-corrected intermediate visual acuity at 66 cm of the SYNTHESIS PLUS TORIC with respect to the SYNTHESIS PLUS IOL.",[23,24,25],"Cataract","Surgery","IOL","RECRUITING","2025-02-10",{"date":29,"type":30},"2025-02-11","ACTUAL",{"date":32,"type":30},"2022-10-10",{"date":34,"type":19},"2025-10",{"name":36,"class":37},"Cutting Edge SAS","INDUSTRY",""]