[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"leishmaniasis-brazilian\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:leishmaniasis-brazilian":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":20,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100519203",false,"NCT06040489","Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly","Inclusion Criteria:\n\n* Active confirmed cutaneous leishmaniasis ou mucosal leishmaniasis\n* Use of highly effective contraceptive method and a negative serologic pregnancy test (beta - HCG), if female in fertile phase\n* Agree and sing informed consent form\n\nExclusion Criteria:\n\n* Previous treatment with leishmanicidal drugs in the last 6 months\n* Pre-treatment electrocardiographic changes that contraindicate the use of liposomal amphotericin B (QTc greater than 450ms)\n* Serum creatinine or urea 1.5 times the upper limit of normal\n* Patients with severe or decompensated liver, kidney, heart disease, Diabetes Mellitus\n* history of any hypersensitivity reaction to liposomal amphotericin B, miltefosine and\u002For pentoxifylline\n* Pregnant and breastfeeding women\n* Patients with Acquired Immunodeficiency Syndrome (AIDS) or other immunodeficiency","ALL","50 Years",{"count":17,"type":18},100,"ESTIMATED","INTERVENTIONAL",[21,22],"PHASE2","PHASE3","Randomised clinical trial comparing oral miltefosine associated with pentoxifylline to intravenous liposomal amphotericin b for the treatment of cutaneous and mucosal leishmaniasis",[25,26],"Leishmaniasis; Brazilian","Leishmaniasis, Mucocutaneous",[28,29,30,31,32,33],"Elderly","Miltefosine","Leishmaniasis","Pentoxifylline","Liposomal amphotericin b","Treatment","RECRUITING","2023-09-13",{"date":37,"type":38},"2023-09-15","ACTUAL",{"date":40,"type":38},"2022-06-22",{"date":42,"type":18},"2026-06",{"name":44,"class":45},"University of Brasilia","OTHER",""]