Locally Advancedrecurrent Or Distant Metastasized Non Small Cell Lung Cancer With Met Overexpression

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Review clinical trials related to Locally Advancedrecurrent Or Distant Metastasized Non Small Cell Lung Cancer With Met Overexpression. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Study to Evaluate the Efficacy and Safety of the Combination of Glumetinib and Docetaxel(Albumin Bound)Verse Docetaxel for the Treatment of MET-overexpressed Non-small Cell Lung Cancer

This study consists of Stage 1 (including dose escalation and dose expansion) and Stage 2 (randomized controlled study). The main purpose of Stage 1 is to preliminarily evaluate the safety and tolerability of the combination of glumetinib Tablets and Docetaxel for Injection(Albumin Bound)(HB1801) in the treatment of MET-overexpressed non-small cell lung cancer (NSCLC); The main purpose of Stage 2 is to evaluate the efficacy of the combination of glumetinib tablets and HB1801 compared to glumetinib tablets monotherapy or docetaxel in the treatment of MET-expressed NSCLC.

Participants needed: 256
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: CSPC ZhongQi Pharmaceutical Technology Co., Ltd.Updated: Jul 29, 2024
Eligibility criteria

1. Able to understand and voluntarily sign a written informed consent form; [+10]

1. Previously received MET-targeted drug therapy; [+25]