[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"loco-regional-anesthesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:loco-regional-anesthesia":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100600798",false,"NCT07102173","Comparison of Loco-regional Analgesic Techniques in Patients Undergoing Video Assisted Thoracoscopic Surgery (VATS)","Management Protocol for Comparison of Loco-regional Analgesic Techniques in Patients Undergoing Video Assisted Thoracoscopic Surgery (VATS)","PRoGEVATS","Inclusion Criteria:\n\n* Adult patients\n* Signed informed consent\n* Elective unilateral surgery\n\nExclusion Criteria:\n\n* Minor patients\n* BMI \\> 40\n* Unstable neurological disorders\n* Known allergy to acetaminophen and NSAIDs\n* Chronic renal failure (stage \\> 4, whith GFR between 29 and 15 mL\u002Fmin)\n* Patient refusal\n* Chronic use of NSAIDs and opioids in the 3 months prior to surgery\n* Contraindications to peripheral block (infection al the insertion site, allergy to local anesthetics, severe coagulation disorders)","ALL","18 Years",{"count":19,"type":20},72,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to compare two loco-regional analgesic techniques:\n\n1. Intercostal nerve block: Performed by the surgeon intraoperatively before final lung re-expansion, involving the administration of 20 mL of 0.5% levobupivacaine using a 27G needle into the subpleural space of the thoracotomy access site and adjacent intercostal spaces.\n2. Ultrasound-guided ESPB: Performed by an anesthesiologist under surgical asepsis with the patient in a seated position. After identifying the target transverse process, a linear ultrasound probe is placed sagittally approximately 2 cm from the midline. The needle (22G, 50 mm) is inserted in-plane in a cranio-caudal direction until contacting the transverse process. After confirming proper injection by observing anesthetic spread between the erector spinae muscle and transverse process, a total of 30 mL of 0.375% ropivacaine is administered.\n\nThis protocol is intended for patients undergoing video-assisted thoracoscopic surgery (VATS) for pneumonectomies, lobectomies, wedge resections, and bullectomies.\n\nPrimary Endpoint:QoR Score at 24 hours (validated questionnaires. Secondary Endpoints: Intraoperative NOL, QoR at 48-72 hours, opioid consumption at 12-24-48 hours, NLR at 24 hours, CPSP incidence at 3 months.",[26],"Loco-regional Anesthesia",[28,29,30,31,32],"VATS","post-operative analgesia","loco-regional anesthesia","ESPB","Intercostal nerve block","NOT_YET_RECRUITING","2025-07-28",{"date":36,"type":37},"2025-08-03","ACTUAL",{"date":39,"type":20},"2025-08-01",{"date":41,"type":20},"2026-04",{"name":43,"class":44},"ASST Sette Laghi","OTHER",""]