[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"lower-extremity-injuries\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:lower-extremity-injuries":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100570659",false,"NCT06710119","Effect of Custom Dynamic Orthoses on Forefoot Loading","LoadsolCP","Patient Inclusion criteria\n\n* Ages: 18-65\n* Sustained a function limiting injury below the knee, requiring a carbon fiber custom dynamic orthosis\n* Shoe size between women's 8 and 13.5 or men's 6.5 and 13\n* Any of the following: weakness of ankle plantarflexors (\\\u003C4\u002F5 on MMT), limited pain free ankle motion (DF\\\u003C10deg or PF\\\u003C20deg), mechanical pain with loading onto hindfoot\u002Fmidfoot\u002Fforefoot (\\>4\u002F10 on verbal numeric pain rating scale), ankle or hindfoot fusion, candidate for ankle or hindfoot fusion, candidate for amputation secondary to ankle\u002Ffoot impairment\n* Ability to walk 25 feet without using a cane or crutch\n* Ability to walk at a slow to moderate pace\n* Able to read and write in English and provide written informed consent\n\nPatient Exclusion criteria\n\n* Pain \\> 9\u002F10 while walking\n* Ankle weakness as a result of spinal cord injury or central nervous system pathology\n* AFO or CDO prescription that includes a knee brace or goes up to thigh\n* Medical or psychological conditions that would preclude functional testing (ex. severe traumatic brain injury, heart condition, clotting disorder, lung condition, stroke, vestibular disorder)\n* Nerve, muscle, bone, or other condition limiting function of the contralateral extremity\n* BMI greater than 40\n* Visual or hearing impairment that limit walking ability or limit the ability to comply with instructions given during testing\n* Pregnancy","ALL","18 Years","65 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","The proposed study is designed to evaluate how foot loading changes during initial accommodation to a carbon fiber custom dynamic orthosis (CDO), after targeted training with or without visual feedback of foot loading, and after take-home use of the CDO. This study will quantify initial offloading associated with CDO use and determine if visual feedback of foot loading and additional take-home use of the CDO can further reduce forces, as orthotists work to provide CDOs to patients.",[26],"Lower Extremity Injuries",[28,29,30,31,32,33],"Gait Analysis","Ankle Foot Orthosis","Carbon Fiber","Biomechanics","Visual Feedback","Foot Loading","RECRUITING","2025-12-29",{"date":37,"type":38},"2025-12-31","ACTUAL",{"date":40,"type":38},"2025-06-18",{"date":42,"type":20},"2027-12-31",{"name":44,"class":45},"University of Iowa","OTHER",2,""]