Malignant Neoplasm Of Bladder

1

Review clinical trials related to Malignant Neoplasm Of Bladder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy

The goal of this clinical trial is to determine if a partial cystectomy with extended pelvic lymph node removal will be effective at treating Muscle-Invasive Bladder Cancer instead of a complete cystectomy with extended pelvic lymph node removal. This clinical trial aims to determine the safety and oncologic efficacy of the intervention, and to examine patient-reported quality of life outcomes in participants. Participants will receive the standard pre-surgery treatment for approximately 4 to 6 weeks. After the pre-surgery treatment is completed, participants will undergo a partial cystectomy with extended pelvic lymph node dissection. After surgery, participants will receive adjuvant systemic therapy.

Participants needed: 40
Trial details
Phase: Phase 2Age: 19+Biological sex: AllType: InterventionalSponsor: Case Comprehensive Cancer CenterUpdated: Jun 5, 2026Locations: 1
Eligibility criteria

Subjects must have histologically confirmed urothelial carcinoma of the bladder,... [+11]

Presence of hydronephrosis. [+8]