[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"mgd-meibomian-gland-dysfunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:mgd-meibomian-gland-dysfunction":39},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":16,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":5},"100643713",false,"NCT07633938","The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled Trial","Inclusion Criteria:\n\n1. Voluntarily participate and sign an informed consent form;\n2. Age range: 18 to 60 years old;\n3. Meet the diagnostic criteria for dry eye in the International Society of Tears and Ocular Surface (TFOS) Dry Eye Symposium (DEWS) II ;\n4. 1\u002F3 or more of the meibomian gland openings are blocked or the secretion characteristics of the meibomian gland are abnormal;\n5. The best corrected visual acuity for each eye is ≥ 0.5;\n6. Eye pressure (IOP) ≥ 5mmHg and ≤ 21mmHg per eye;\n7. Women with reproductive potential agree to use reliable contraceptive methods during the study period;\n8. Willing and able to complete all planned research visits and follow the guidance of the researchers.\n\nExclusion Criteria:\n\n1. Contact lens use: Having used contact lenses within 14 days prior to the screening visit, or refusing to commit to discontinuing contact lens use during the study period (within the next 2 months);\n2. Had undergone corneal refractive surgery (e.g., LASIK\u002FSMILE), other corneal surgeries, cataract surgery, anti-glaucoma surgery, or fundoscopic surgery within 12 months prior to enrollment screening;\n3. Participation in other medical studies within 3 months prior to enrollment screening;\n4. Presence of any of the following active ocular diseases at present or within 3 months prior to screening: I) Acute allergic conjunctivitis; II) Infection (by bacteria, viruses, fungi, etc.); III) Inflammation (e.g., keratitis, retinitis).\n\n   Meningitis, choroiditis, uveitis, scleritis, etc.;\n5. Eyelid abnormalities affecting eyelid function (such as ptosis, blepharospasm, entropion, ectropion, etc.);\n6. Extensive ocular surface scars or conditions that may compromise ocular surface integrity (e.g., Stevens-Johnson syndrome, history of chemical burns, persistent corneal epithelial defects, history of ocular trauma, etc.);\n7. Currently or previously diagnosed with glaucoma, or undergoing treatment with anti-glaucoma medications;\n8. Has used any of the following ocular medications within the past 1 month: immunosuppressants, nonsteroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, or perfluorohexyloctane;\n9. Has received any of the following non-pharmacological treatments for dry eye within the past month: meibomian gland massage, deep eyelid margin cleansing, intense pulsed light therapy, or thermal pulsation therapy;\n10. During pregnancy or lactation;\n11. Neurological or psychiatric disorders (moderate to severe anxiety, depression, and sleep disorders);\n12. Uncontrolled ocular or systemic diseases;\n13. History of epilepsy;\n14. The investigator determines that the subject is not suitable for participation in this study.","ALL","18 Years","60 Years",{"count":18,"type":19},142,"ESTIMATED","INTERVENTIONAL",[22],"NA","This study aims to conduct a randomized controlled clinical trial to compare the efficacy of a new type of massage device - eyelid support plate and glass rod assisted eyelid massage in improving MGD related dry eye symptoms, and evaluate the comfort and efficiency of both treatments, providing evidence-based support for clinical work",[25,26],"Dry Eye Disease (DED)","MGD-Meibomian Gland Dysfunction","NOT_YET_RECRUITING","2026-06-08",{"date":30,"type":31},"2026-06-11","ACTUAL",{"date":33,"type":19},"2026-07-01",{"date":35,"type":19},"2027-09-01",{"name":37,"class":38},"Zhongshan Ophthalmic Center, Sun Yat-sen University","OTHER",""]