[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"motor-neuron-disease--amyotrophic-lateral-sclerosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:motor-neuron-disease--amyotrophic-lateral-sclerosis":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100449725",false,"NCT05136222","Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease","A Multi-centre Randomised Controlled Trial of Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease (PSG4NIVinMND; 3, Three Letter Acronyms [3TLA])","3TLA","Inclusion Criteria:\n\n* Age \\>18 years\n* Clinical indication to commence long term NIV\n* Confirmed clinical diagnosis of underlying condition\n\nExclusion Criteria:\n\n* Medically unstable\n* Hypoventilation attributable to medications with sedative\u002Frespiratory depressant side- effects\n* Use of NIV for more than 1 month in the previous 3 months\n* Inability to provide informed consent\n* Previous intolerance of NIV","ALL","18 Years",{"count":19,"type":20},244,"ESTIMATED","INTERVENTIONAL",[23],"NA","A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.",[26],"Motor Neuron Disease \u002F Amyotrophic Lateral Sclerosis",[28,29,30,31,32],"Non-invasive ventilation","Polysomnography","Sleep study","Amyotrophic lateral sclerosis","Chronic respiratory failure","RECRUITING","2022-06-19",{"date":36,"type":37},"2022-06-23","ACTUAL",{"date":39,"type":37},"2021-12-15",{"date":41,"type":20},"2028-02-28",{"name":43,"class":44},"University of Melbourne","OTHER",13,""]