[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"myocardial-blood-flow-reserve\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:myocardial-blood-flow-reserve":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100590602",false,"NCT06969547","Mechanical Dyssynchrony and Microvascular Dysfunction by SPECT","Evaluation the Capabilities of Cardiac Mechanical Dyssynchrony in the Diagnosis of Myocardial Microvascular Dysfunction in Chronic Ischemic Heart Disease","MD&MD","Inclusion Criteria:\n\n* Ischemia with no obstructive coronary arteries (INOCA)\n* Obstructive coronary artery disease (CAD)\n* Patients without evidence of coronary heart disease\n\nExclusion Criteria:\n\n* Left ventricular ejection fraction \\\u003C55% according to echocardiography;\n* History of myocardial infarction\u002Frevascularization;\n* hypertension: systolic blood pressure \\>180 mm Hg. Art., diastolic BP\\>110 mm Hg. Art.;\n* systolic arterial hypotension \\\u003C80 mm Hg. Art.;\n* atrial fibrillation;\n* AV blockade of the III degree; sick sinus syndrome;\n* massive pulmonary embolism (PE) with a high degree of pulmonary hypertension;\n* the presence of significant valvular pathology (mitral insufficiency ≥ 3 degrees, aortic insufficiency ≥ 3 degrees, tricuspid regurgitation ≥ 3 degrees).\n* severe course of bronchial asthma, chronic obstructive pulmonary disease;\n* decompensated type 2 diabetes,\n* severe liver or kidney failure (glomerular filtration rate \\\u003C50 ml\u002Fmin\u002F1.73 m3 (CKD-EPI),\n* morbid obesity (body mass index \\>45);\n* history of myocarditis\n* indications of poor drug tolerance;\n* oncological diseases;\n* chronic alcoholism, mental disorders;\n* other severe comorbidity,\n* refusal to participate in the study.",true,"ALL","18 Years","75 Years",{"count":21,"type":22},75,"ESTIMATED","OBSERVATIONAL","The project is aimed at studying the feasibility of mechanical dyssynchrony of the left ventricle of the heart, determined by SPECT (gated MPI), as well as its stress-induced dynamics, in the evaluation of patients with coronary microvascular dysfunction in chronic coronary heart diseasу.",[26,27,28],"Myocardial Blood Flow Reserve","Mechanical Dyssynchrony","Coronary Arterial Disease (CAD)",[30,31,32,33,34],"SPECT","gated MPI","mechanical dyssynchrony","dobutamine","myocardial bloow flow reserve","RECRUITING","2025-09-22",{"date":38,"type":39},"2025-09-24","ACTUAL",{"date":41,"type":39},"2023-10-01",{"date":43,"type":22},"2026-05-15",{"name":45,"class":46},"Tomsk National Research Medical Center of the Russian Academy of Sciences","OTHER",""]