[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"nasality\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:nasality":49},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100616085",false,"NCT07301021","Velopharyngeal Insufficiency After Maxillomandibular Advancement Osteotomy in Obstructive Sleep Apnea Patients","VPIMMA","Inclusion Criteria:\n\n* Age \\> 18 years\n* Mild to severe OSA\n* Indication for MMA for OSA treatment\n\nExclusion Criteria:\n\n* patients who underwent other adjunctive procedures at the time of MMA (e.g., multipiece le Fort osteotomy, TMJ reconstruction\n* Previous history of orthognathic surgery\n* Previous history of orthognathic surgery\n* Previous history of oropharyngeal surgery (UPPP or multi-level surgery)\n* Cleft palate and syndromic patients\n* Neuromusculair diseases which causes VPI, dysphagia or dysarthria\n* Incapacity",true,"ALL","18 Years",{"count":19,"type":20},28,"ESTIMATED","2 Years","OBSERVATIONAL","The aim of this study is to gain insight into the development of velopharyngeal insufficiency (VPI) in patients who have undergone maxillomandibular advancement osteotomy (MMA) as a treatment for obstructive sleep apnea syndrome (OSAS). A speech therapist evaluates nasality, speech, and swallowing before and after the surgery.",[25,26,27,28],"Velopharyngeal Insufficiency","Swallowing","Nasality","Speech",[30,31,32,33,34,35,36],"maxillomandibular advancement","obstructive sleep apnea","velopharyngeal insufficiency","speech therapy","swallowing","nasality","speech","NOT_YET_RECRUITING","2026-03-18",{"date":40,"type":41},"2026-03-20","ACTUAL",{"date":43,"type":20},"2026-05-01",{"date":45,"type":20},"2027-12-01",{"name":47,"class":48},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","OTHER",""]