[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neobladder-diversion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neobladder-diversion":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100530700",false,"NCT06190197","Prophylactic Antibiotics in Cystectomy With Diversion","Prophylactic Antibiotics in Radical Cystectomy With Urinary Diversion","Inclusion Criteria:\n\n* Presence of muscle invasive bladder cancer and planning to undergo radical cystectomy with either ileal conduit or neobladder diversion.\n* 18 years of age or older\n\nExclusion Criteria:\n\n* Currently receiving antimicrobials for active infection\n* Poor renal function with GFR \\\u003C 30 ml\u002Fmin\n* Allergy to nitrofurantoin and unable to take an alternative antibiotic (cephalexin, trimethoprim-sulfamethoxazole, or ciprofloxacin)\n* Pregnancy\n* Unable to provide Informed consent\n* Prior pelvic radiation","ALL","18 Years",{"count":18,"type":19},120,"ESTIMATED","INTERVENTIONAL",[22],"EARLY_PHASE1","Using a randomized 2 arm design, this study is being conducted to test for non-inferiority of no prophylactic antibiotic therapy versus the prophylactic oral antibiotic, nitrofurantoin, through comparison of rates of postoperative urinary tract infections within the 90-day postoperative period in patients with muscle invasive bladder cancer who undergo radical cystectomy with urinary diversion.",[25,26,27,28],"Muscle-Invasive Bladder Carcinoma","Radical Cystectomy","Ileal Conduit","Neobladder Diversion","RECRUITING","2025-11-13",{"date":32,"type":33},"2025-11-17","ACTUAL",{"date":35,"type":33},"2024-05-13",{"date":37,"type":19},"2027-10-15",{"name":39,"class":40},"University of Minnesota","OTHER",""]