[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neurobehavioral-components-of-reward-and-loss-valuation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neurobehavioral-components-of-reward-and-loss-valuation":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100468774",false,"NCT05384158","Valuation in Depressed Mood, Anhedonia, and Anxiety","Evaluating Overlap and Distinctiveness in Neurocomputational Loss and Reward Elements of the RDoC Matrix","Inclusion Criteria:\n\n* mood, anxiety, or anhedonia symptoms that affect functioning; fluent in English; able to see computer display; able to perform simple computer games.\n\nExclusion Criteria:\n\n* history of seizure disorder, stroke, or head injury with more than 10 minutes of unconsciousness; hormone disorder; electroconvulsive therapy within 5 years; history of chemotherapy for cancer; current pregnancy; contraindications to MRI","ALL","25 Years","50 Years",{"count":19,"type":20},252,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study examines how people respond to rewards and losses, and the extent to which these responses are linked or distinct among people experiencing depressed mood, anhedonia, and\u002For anxiety.",[26],"Neurobehavioral Components of Reward and Loss Valuation",[28,29,30],"depression","anxiety","anhedonia","RECRUITING","2025-09-02",{"date":34,"type":35},"2025-09-09","ACTUAL",{"date":37,"type":35},"2021-08-01",{"date":39,"type":20},"2026-07",{"name":41,"class":42},"Virginia Polytechnic Institute and State University","OTHER",""]