[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"neuromuscular-monitoring\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:neuromuscular-monitoring":38},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":33,"leadSponsor":35,"locationsCount":4},"100580244",false,"NCT06834776","Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using Patients","Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using Patients Undergoing Elective Surgery Under General Anesthesia, Monitored by Train-of-Four (TOF)","Inclusion Criteria:\n\n* Age 18-75 years\n* ASA classification I, II, III\n* BMI 18-30\n* Statin use for at least 3 months or no prior statin use\n* Elective surgery requiring general anesthesia with endotracheal intubation\n* Signed informed consent for participation in the study\n\nExclusion Criteria:\n\n* ASA classification IV or higher\n* BMI \\\u003C18 or \\>30\n* History of liver or renal insufficiency (creatinine \\>1.6, liver function tests \\>2x normal)\n* Neuromuscular, psychiatric, or neurological disorders\n* Pregnancy\n* Use of drugs affecting neuromuscular function (e.g., anticonvulsants, aminoglycosides)\n* History of malignant hyperthermia\n* Respiratory disorders, including sleep apnea\n* Allergy to anesthetic drugs used in the study","ALL","18 Years","75 Years",{"count":19,"type":20},104,"ESTIMATED","OBSERVATIONAL","This study aims to compare the neuromuscular blockade responses in patients undergoing elective surgery under general anesthesia, with a focus on the use of statins. The study will assess the depth of neuromuscular blockade, recovery time, and postoperative residual curarization using Train-of-Four (TOF) monitoring, with the primary goal of determining whether statin use alters the neuromuscular blockade management.",[24,25,26],"Neuromuscular Blockade","Statin-Associated Myopathy","Neuromuscular Monitoring","NOT_YET_RECRUITING","2025-02-15",{"date":30,"type":31},"2025-02-19","ACTUAL",{"date":28,"type":20},{"date":34,"type":20},"2025-12-15",{"name":36,"class":37},"Ankara City Hospital Bilkent","OTHER",""]