[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"non-convulsive-status-epilepticus\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:non-convulsive-status-epilepticus":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100459519",false,"NCT05263674","Fast Acute Sedation at Intensive Care vs. High-dose i.v. Anti-seizure Medication for Treatment of Non-convulsive Status Epilepticus (FAST-trial)","FAST","Inclusion Criteria:\n\n* Adult patients (older than 18 years) with EEG-verified NCSE, according to the Salzburg criteria, who have not responded to appropriate treatment with benzodiazepines and at least one 2nd line i.v. anti-seizure medication according to the current Danish national neurological treatment guidelines (Levetiracetam, Fosfenytoin or Valproate).\n\nExclusion Criteria:\n\n* patients with epilepticus status due to acute neuroinfection (e.g. bacterial meningitis or viral encephalitis)\n* acute traumatic or spontaneous intracranial hemorrhage\n* suspicion of cerebral anoxia \u002F hypoxia \u002F hypoglycemia \u002F epileptic encephalopathy\n* contraindications to anti-seizure medication defined in the protocol\n* contraindications to anesthesia treatment in intensive care\n* focal motor status epilepticus without relevant conscious influence (Glasgow Coma Scale\\> 13)\n* known epileptic encephalopathy\n* Clinical need for acute intubation","ALL","18 Years","120 Years",{"count":19,"type":20},140,"ESTIMATED","INTERVENTIONAL",[23],"PHASE3","This open-label, randomized multicenter trial aims at clarifying the standard of care of patients with non-convulsive status epilepticus not responding to treatment with benzodiazepines and at least one high-dose intra venous anti-seizure medication.",[26],"Non-Convulsive Status Epilepticus","RECRUITING","2026-05-01",{"date":30,"type":31},"2026-05-04","ACTUAL",{"date":33,"type":31},"2022-02-07",{"date":35,"type":20},"2028-12-31",{"name":37,"class":38},"University of Southern Denmark","OTHER",5,""]