[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"obessive-compulsive-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:obessive-compulsive-disorder":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100630213",false,"NCT07484750","Efficacy and Influencing Factors of Mindfulness-Based Exposure Group Therapy for OCD","Mindfulness-Based Exposure Group Therapy for Obsessive-compulsive Disorder: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Have a primary diagnosis of Obsessive-Compulsive Disorder (OCD) according to DSM-5 criteria\n* Are between 16 and 55 years of age (inclusive)\n* Have a Yale-Brown Obsessive Compulsive Scale (Y-BOCS) total score ≥ 16\n* Have an education level of junior high school or above\n* Are medication-free or have been stabilized on psychotropic medication for at least 8 weeks\n* Have sufficient visual and auditory capabilities to complete study assessments\n* Are willing to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Meet DSM-5 criteria for any other psychiatric disorder besides OCD\n* Have severe OCD symptoms that prevent completion of assessments\n* Exhibit active suicidal ideation or high suicide risk\n* Have a serious somatic disease, central nervous system disease, or substance abuse history\n* Are pregnant, breastfeeding, or planning pregnancy\n* Have metal implants contraindicated for MRI (e.g., pacemakers, intracranial clips, metal dentures, arterial stents, joint fixations)","ALL","16 Years","55 Years",{"count":19,"type":20},64,"ESTIMATED","INTERVENTIONAL",[23],"NA","Obessive-Compulsive Disorder (OCD) is frequently treatment-refractory and imposes a substantial burden on affected individuals. Although Exposure and Response Prevention (ERP) is widely regarded as the first-line intervention, its inherently distressing nature contributes to treatment refusal and premature dropout in a subset of patients. The present study aims to develop and validate a novel intervention, Mindfulness-Based Exposure Therapy (MBET).\n\nIn contrast to existing protocols that incorporate mindfulness as an adjunct to ERP and have yielded mixed or limited benefits, this study seeks a theoretically grounded integration of mindfulness and exposure-based principles. We hypothesize that mindfulness training improves emotion regulation, thereby producing a synergistic effect that enhances patients' capacity to engage in and complete exposure tasks.\n\nFrom a clinical perspective, MBET is intended to offer a more tolerable and acceptable alternative to standard ERP, with the potential to improve treatment adherence and clinical outcomes among patients who experience traditional exposure procedures as excessively distressing.",[26],"Obessive-Compulsive Disorder",[28,29],"mindfulness","Exposure and Response Prevention","RECRUITING","2026-03-16",{"date":33,"type":34},"2026-03-20","ACTUAL",{"date":36,"type":34},"2026-02-03",{"date":38,"type":20},"2029-06-30",{"name":40,"class":41},"Shanghai Mental Health Center","OTHER",""]