Oligoprogressive Lung Non Small Cell Carcinoma

1

Review clinical trials related to Oligoprogressive Lung Non Small Cell Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A PET Imaging Agent (64Cu-DOTA-Pembrolizumab) for Determining Treatment Response Among Patients With Stage IV Non-small Cell Lung Cancer Receiving Pembrolizumab

This phase I trial studies the safety and side effects of a new positron emission tomography (PET) imaging agent called 64Cu-DOTA-pembrolizumab to see how well it works in determining treatment response for patients with stage IV non-small cell lung cancer (NSCLC) already receiving pembrolizumab. 64Cu-DOTA-pembrolizumab consists of a monoclonal antibody, pembrolizumab, that binds to a protein called PD-1 that is expressed on tumor cells. PET scans can then visualize the tumor cells using 64Cu, a radioactive substance. 64Cu-DOTA-pembrolizumab PET scans may be safe and useful to doctors in telling the difference between tumors that are still growing and areas that are not growing in patients with stage IV NSCLC receiving pembrolizumab treatment.

Participants needed: 6
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: City of Hope Medical CenterUpdated: Jun 2, 2026Locations: 1
Eligibility criteria

Documented informed consent of the participant and/or legally authorized represe... [+18]

Patient planned to stop pembrolizumab at time of referral for SBRT [+12]