[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"parkinson-disease-mild-cognitive-impairment\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:parkinson-disease-mild-cognitive-impairment":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100565322",false,"NCT06640673","Electrophysiological Signature of Mild Cognitive Impairment and Its Relationship with Parkinson's Disease: a High-density EEG Investigation","MMCI","Inclusion Criteria:\n\n* Upper score \\>24 MMSE or \\>15.5 Moca\n* If taking medications, taking stable doses for at least 4 weeks prior to the inclusion visit - of anticholinesterase drugs (donepezil, memantine, rivastigmine, ...) or antidepressants (SSRIs, tricyclics, SNARI, ...) or Levodopa.\n* Having signed the informed consent\n\nExclusion Criteria:\n\n* Subjects with severe dementia ( MMSE \\\u003C 24 )\n* Lower score \\\u003C15.5 Moca\n* Subjects on antipsychotic treatment for less than 3 months\n* Subjects with uncontrolled comorbidities\n* Subjects with metal prostheses or dentures and in general conditions for which MRI examinations are prevented.\n* Subjects with an inability to walk independently.",true,"ALL","50 Years","90 Years",{"count":20,"type":21},42,"ESTIMATED","OBSERVATIONAL","The study aims to investigate neural correlate of Mild Cognitive Impairment (MCI) in Parkinson's disease (PD) and to identify a link between functional impairment (in both cognitive and motor domains) and electrophysiological cortical sing of MCI in PD. A sample of 42 subjects will be divide into three subgroup: healthy control, PD with MCI (PD-MCI) and PD without MCI (PD-ctrl). Those subjects will undergo a specific neuropsychological evaluation and, to measure the electro-cortical activity, high-density electroencephalography (hdEEG) will be record during both resting state and cognitive tasks. Furthermore, hdEEG data will be combine with structural magnetic resonance to obtain information about network connectivity.",[25,26,27],"Parkinson Disease","Parkinson Disease, Mild Cognitive Impairment","Healthy",[29,30,31,32],"MCI in PD","Mild Cognitive Impairment","Parkinson's disease","Hd-EEG","RECRUITING","2024-10-11",{"date":36,"type":37},"2024-10-15","ACTUAL",{"date":39,"type":37},"2023-06-18",{"date":41,"type":21},"2025-05",{"name":43,"class":44},"IRCCS San Camillo, Venezia, Italy","OTHER",""]