Patients With Advanced Non Small Cell Lung Cancer With Meningeal Progression After Osimertinib Treatment

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Review clinical trials related to Patients With Advanced Non Small Cell Lung Cancer With Meningeal Progression After Osimertinib Treatment. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Zorifertinib With Osimertinib for NSCLC With Meningeal Progression

This is a clinical trial that aims to test Zorifertinib when used together with a known drug, Osimertinib. The goal is to learn if this combination is safe and works for people with advanced Non-Small Cell Lung Cancer (NSCLC) whose cancer has spread to the membranes surrounding the brain and spinal cord (a condition called leptomeningeal metastases) after being treated with Osimertinib.

Participants needed: 42
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Alpha Biopharma (Jiangsu) Co., Ltd.Updated: Jun 22, 2026Locations: 5
Eligibility criteria

The patient or the guardian is required to understand and sign the informed cons... [+17]

Subjects who plan to receive brain radiotherapy or intrathecal injection during... [+6]