Pediatric Dentistry

7

Review clinical trials related to Pediatric Dentistry. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Occlusal Changes After Modified Hall Technique in Molars Affected by Molar-Incisor Hypomineralization

Molar-incisor hypomineralization (MIH) frequently affects permanent first molars and increases the risk of rapid post-eruptive breakdown and restorative failure. Stainless steel crowns (SSCs) are considered a reliable treatment option for severely affected molars; however, SSC placement may temporarily alter the occlusal vertical dimension and occlusal contacts. Quantitative evidence describing the occlusal adaptation process following SSC placement in MIH-affected permanent molars is limited. This prospective longitudinal clinical study aims to evaluate occlusal adaptation after SSC placement using the modified Hall technique in MIH-affected permanent first molars. Forty-six children will be included. Intraoral scans will be obtained at baseline, immediately after treatment, and during follow-up visits up to 3 months. Digital models will be superimposed to measure three-dimensional changes in cusp position, occluso-vertical dimension, and occlusal contact area. Temporomandibular joint function and periodontal parameters will also be assessed. The results are expected to provide quantitative evidence on occlusal adaptation following SSC treatment in MIH-affected molars.

Participants needed: 46
Trial details
Age: 6-14Biological sex: AllType: InterventionalSponsor: Ankara Yildirim Beyazıt UniversityUpdated: Apr 17, 2026Locations: 1
Eligibility criteria

Absence of any skeletal anomalies [+11]

Individuals with serious systemic or psychological conditions [+2]

Status: Recruiting

AI Avatar Video vs. Tell-Show-Do for Reducing Anxiety and Improving Cooperation in Children During Local Anesthesia

This randomized clinical trial aims to compare two behavior guidance techniques used to reduce anxiety in children during local anesthesia injections in dental treatment. The study evaluates the traditional Tell-Show-Do (TSD) technique versus an artificial intelligence (AI)-driven, avatar-based video method called the "Mini Dentist." Children aged 5 to 7 years who require local anesthesia for routine dental treatment will be randomly assigned to one of two groups. The control group will receive the conventional Tell-Show-Do explanation from the pediatric dentist. The experimental group will watch a short animated video featuring an AI-generated avatar that explains and demonstrates the procedure in a child-friendly manner before the injection. Anxiety and behavior will be assessed using heart rate monitoring, behavioral observation (FLACC scale), and a self-reported pain scale (Wong-Baker FACES). The goal is to determine whether the AI-based method improves cooperation and reduces anxiety compared to the traditional approach. Participation is voluntary, and all procedures follow ethical research standards.

Participants needed: 70
Trial details
Age: 5-7Biological sex: AllType: InterventionalSponsor: Saint-Joseph UniversityUpdated: Mar 30, 2026Locations: 1
Eligibility criteria

Children aged 5 to 7 years [+6]

History of epilepsy [+5]

Status: Recruiting

Occlusal Impact of Hall Crowns in Primary Molars

Hall Technique is a non-invasive restorative approach for managing carious primary molars, increasingly used in pediatric dentistry due to its simplicity and patient tolerance. This study aims to evaluate and compare the occlusal changes that occur following Hall crown placement on different primary molar groups (maxillary first molar, maxillary second molar, mandibular first molar, mandibular second molar) using digital model analysis.

Participants needed: 60
Trial details
Age: 7-10Biological sex: AllType: InterventionalSponsor: Ankara Yildirim Beyazıt UniversityUpdated: Nov 20, 2025Locations: 1
Eligibility criteria

No skeletal or dental anomalies, [+19]

Individuals with serious systemic or psychological conditions [+2]

Status: Not yet recruiting

Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars

This randomized clinical trial aims to evaluate and compare the antimicrobial efficacy of Moringa Oleifera leaf extract versus sodium hypochlorite as root canal irrigants in pulpectomy of nonvital primary molars in pediatric patients. The study will assess bacterial reduction using blood agar

Participants needed: 38
Trial details
Age: 4-7Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jun 3, 2025Locations: 1
Eligibility criteria

Children aged 4 to 7 years [+3]

Medically compromised or uncooperative children [+4]

Status: Recruiting

Evaluation of Band-Loop Space Maintainers Produced With Three-Dimensional Printer and Conventional Technique

Our research is planned as a randomised clinical trial. The main aim of our study is to evaluate the clinical success of band and loop space maintainers produced by three-dimensional printer and conventional technique and the changes they cause in periodontal tissues.

Participants needed: 27
Trial details
Age: 5-8Biological sex: AllType: InterventionalSponsor: Aydin Adnan Menderes UniversityUpdated: Jan 29, 2025Locations: 1
Eligibility criteria

Systemically healthy children [+6]

Patients with systemic diseases [+1]

Status: Not yet recruiting

Comparing Minimally Invasive Techniques Used In Treatment Of Carious Primary Molars In Children

Dental caries is a natural process by which bacteria in the biofilm causes fluctuations in the pH, which leads to enamel erosion and result in visible lesions. If left untreated, caries will progress and result in pain, abscess, and systemic infection, leading to functional and/or psychosocial impairment which is a serious problem Caries is, in fact, the most prevalent childhood disease in the world and is most prominent among low-economic populations. So, the main goal is to minimize Dental caries as much as possible by applying preventive measures to reduce the occurrence and progression of dental caries. In that scope, both Atraumatic Restorative Treatment (ART) and the Hall Technique (HT) were created as part of Minimal Invasive Dentistry (MID) to slow the downward restorative spiral and reduce discomfort during the treatment as neither of which requires the administration of local anesthesia nor the use of rotary instruments. According to a retrospective analysis, utilizing the Hall technique to seal cavities performed much better than using conventional restorations. statistically and clinically during 10 years of follow-up. Since ART is associated with lower levels of anxiety, pain, and discomfort than traditional dentistry procedures, it has become widely employed in pediatric dentistry. Despite having reduced survival rates in multiple-surface restorations, ART is still regarded as a viable, evidence-based choice for treating and preventing caries lesions in primary posterior teeth since it is a quick, inexpensive, and comfortable procedure for the patient.

Participants needed: 68
Trial details
Age: 4-6Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Sep 19, 2024Locations: 1
Eligibility criteria

Age: From 4 to 6 years. [+3]

Presence of signs and symptoms of necrosis. [+2]

Status: Recruiting

Evaluation of PEEK and BruxZir as Esthetic Space Maintainers in Children

Compare two band and loop space maintainers made from two tooth colored materials; Polyetherethherketone (PEEK) and monolithic Zirconia (BruxZir) as regards to: * Clinical performance of space maintainers in terms of frequency of debonding or fracture of the appliance and health of adjacent gingiva during a one-year follow up. * Wear of the opposing teeth.

Participants needed: 20
Trial details
Age: 6-11Biological sex: AllType: InterventionalSponsor: Ain Shams UniversityUpdated: Aug 19, 2024Locations: 1
Eligibility criteria

Children requiring bilateral extraction of mandibular first primary molars or th... [+5]

Carious abutment teeth requiring pulp therapy. [+4]