[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"periodontal-intrabony-defects\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:periodontal-intrabony-defects":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100637310",false,"NCT07613606","Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defects","Injectable Platelet-Rich Fibrin (i-PRF) With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defects: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients of both genders \\>18 years old, medically free of systemic diseases affecting periodontal regeneration.\n* Diagnosis of 'periodontitis' stage III (grades B or C).\n* Single-rooted and multi-rooted vital teeth in either the maxilla or the mandible.\n* Presence of comparable bilateral two- or three-walled intrabony defects \\[probing pocket depth (PPD), \\> 5 mm with intrabony defect depth ≥ 3 mm, from the alveolar crest to the defect base, at screening radiograph\\] not in a furcation-involved tooth.\n\nExclusion Criteria:\n\n* Patients with systemic illness known to affect the outcome of periodontal therapy, including diabetes, immune deficiencies, etc.\n* Pregnant and lactating women\n* Current use of any form of tobacco.\n* Non-surgical periodontal treatment in the past 6 months, or surgical periodontal treatment in the past 12 months.\n* Degree 2 or 3 mobility of the involved sites.6.\n* Presence of periapical pathology, acute infection, or subgingival restoration which could interfere with clinical measurements.","ALL","18 Years",{"count":18,"type":19},40,"ESTIMATED","INTERVENTIONAL",[22],"NA","This study aims to clinically and radiographically evaluate the adjunctive effect of injectable platelet-rich fibrin (i-PRF) used in combination with a minimally invasive non-surgical technique for the regenerative treatment of intrabony periodontal defects.",[25,26,27],"Platelet-Rich Fibrin","Minimally Invasive Non-Surgical Technique","Periodontal Intrabony Defects","RECRUITING","2026-05-21",{"date":31,"type":32},"2026-05-29","ACTUAL",{"date":34,"type":32},"2026-03-01",{"date":36,"type":19},"2026-12-01",{"name":38,"class":39},"October 6 University","OTHER",""]