[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"phantom-pain-following-amputation-of-lower-limb\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:phantom-pain-following-amputation-of-lower-limb":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100596351",false,"NCT07044323","Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment","PLP Home-Based","Inclusion Criteria:\n\n* Age 18 -100\n* Capacity to provide Informed Consent\n* Unilateral above or below knee amputation more than 3 months prior to enrollment\n* Absence of cognitive impairment, operationally defined as a Montreal Cognitive Assessment score of 18 or greater1.\n* Pain averaged over the preceding 1 month in the phantom limb rated as greater than 4 on a scale of 0-10.\n\nExclusion Criteria:\n\n* History of significant medical or neurological disorder such as stroke or moderate to severe traumatic brain injury (operationally defined as loss of consciousness for more than 30 minutes)\n* History of significant or poorly controlled psychiatric disorders\n* Substantial depression or anxiety affecting their ability to perform tasks necessary for the study.\n* Current abuse of alcohol or drugs, prescription or otherwise\n* Nursing a child, pregnant, or intent to become pregnant during the study","ALL","18 Years","100 Years",{"count":19,"type":20},44,"ESTIMATED","INTERVENTIONAL",[23],"NA","After amputation of an arm or leg, up to 90% of subjects experience a \"phantom limb\", a phenomenon characterized by persistent feelings of the missing limb. Many subjects with a phantom limb experience intense pain in the missing extremity that is often poorly responsive to medications or other interventions. The study will explore the feasibility and efficacy of a home-based, active VR treatment for phantom limb pain (PLP).",[26,27],"Phantom Pain Following Amputation of Lower Limb","Amputation",[29,30,31,32],"pain","phantom limb","lower limb amputation","treatment","RECRUITING","2025-08-07",{"date":36,"type":37},"2025-08-08","ACTUAL",{"date":39,"type":37},"2025-06-16",{"date":41,"type":20},"2026-05-31",{"name":43,"class":44},"Albert Einstein Healthcare Network","OTHER",3,""]