[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"porphyria-acute-intermittent\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:porphyria-acute-intermittent":38},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":4,"eligibilityCriteria":13,"healthyVolunteers":10,"sex":14,"minAge":15,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":20,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":32,"leadSponsor":34,"locationsCount":37},"100537116",false,"NCT06273644","Clinical Research on Acute Intermittent Porphyria and the Use of Carbohydrate-Rich Diet as a Treatment","Inclusion Criteria:\n\n* Diagnosis of AIP\n\nExclusion Criteria:\n\n* Not having diagnosis of AIP\n* Undergoing treatment as part of other clinical research on AIP\n* Pregnancy\n* Diabetes\n* Below 18 years of age","ALL","18 Years",{"count":17,"type":18},50,"ESTIMATED","INTERVENTIONAL",[21],"NA","The main aim of this clinical trial is to learn about the effect of carbohydrate-rich diet as a treatment for AIP (acute intermittent porphyria).\n\nAim: Investigate the diet's impact on tissue and serum glucose, plasma insulin, cytokine levels, amino acids, and gut microbiota in AIP, and their correlation with PBG (Porphobilinogen).\n\nAim: Assess the diet's effect on AIP symptoms and health status in AIP. Aim: Measure the effect of a high-carbohydrate diet on mitochondrial activity in AIP Aim: Map and detect potential mutations in mitochondrial genomic DNA in AIP Aim: Discover new markers in AIP through RNA sequencing and machine learning.\n\nParticipants will follow two diet plans, a 4-week intervention with 60-65 E% carbohydrates and a 4 week intervention with 40-45 E% carbohydrates.",[24],"Porphyria, Acute Intermittent","RECRUITING","2026-03-25",{"date":28,"type":29},"2026-03-27","ACTUAL",{"date":31,"type":29},"2024-01-27",{"date":33,"type":18},"2037-12-31",{"name":35,"class":36},"Nordlandssykehuset HF","OTHER",3,""]