[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-operative-atrial-fibrillation-after-coronary-artery-bypass-grafting-cabg\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-operative-atrial-fibrillation-after-coronary-artery-bypass-grafting-cabg":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100637774",false,"NCT07611019","Colchicine for the Prevention of Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Single-Center, Strategy-Stratified, Randomized, Double-Blind, Placebo-Controlled Trial","Randomized, Double-Blind, Placebo-Controlled Trial of Colchicine to Prevent Post-Operative Atrial Fibrillation After CABG With Strategy-Stratified Randomization","Inclusion Criteria:\n\n* Adults aged 20 years or older scheduled to undergo elective coronary artery bypass grafting (CABG), including either off-pump CABG or on-pump CABG.\n* Ability to receive oral study medication before and after surgery.\n* Provision of written informed consent before randomization.\n\nExclusion Criteria:\n\n* History of atrial fibrillation or atrial flutter before surgery.\n* Severe renal impairment (estimated glomerular filtration rate \\\u003C30 mL\u002Fmin\u002F1.73 m²) or chronic dialysis.\n* Severe hepatic dysfunction.\n* Known hypersensitivity or previous severe adverse reaction to colchicine.\n* Pregnancy or breastfeeding.\n* Current use of strong CYP3A4 or P-glycoprotein inhibitors that cannot be safely discontinued or substituted.\n* Any condition judged by the investigators to interfere with study participation or safety assessment.","ALL","20 Years",{"count":18,"type":19},400,"ESTIMATED","INTERVENTIONAL",[22,23],"PHASE2","PHASE3","Post-operative atrial fibrillation after coronary artery bypass grafting (CABG)",[26],"Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)",[28,29,30,31,32,33,34,35],"colchicine","postoperative atrial fibrillation","coronary artery bypass grafting","off-pump surgery","cardiopulmonary bypass","pharmacokinetics","inflammation","neutrophil extracellular traps","NOT_YET_RECRUITING","2026-05-20",{"date":39,"type":40},"2026-05-28","ACTUAL",{"date":42,"type":19},"2026-06",{"date":44,"type":19},"2028-07",{"name":46,"class":47},"National Taiwan University Hospital","OTHER",""]