[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"post-viral-fatigue\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:post-viral-fatigue":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100505866",false,"NCT05866952","Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection","Quantitative Computed Tomography to Assess Ventilatory and Perfusion Abnormalities in Individuals With Post-Acute Sequelae of SARS-CoV-2 Infection","PASC VQ","Inclusion Criteria:\n\n* Age ≥ 18\n* Self-reported or documented SARS-CoV-2 infection by RT-PCR or Antigen testing \\> 3 months ago or no previous history of SARS-CoV-2 infection (control group only)\n* Normal or mild abnormalities on baseline Pulmonary Function Tests (PFTs)\n* New or worsening symptoms of chronic fatigue, dyspnea or exercise intolerance after COVID-19 with otherwise unclear etiology (PASC group only)\n\nExclusion Criteria:\n\n* SARS-CoV-2 infection by RT-PCR or Antigen testing within the last 3 months\n* Inability to provide consent or non-English speaking\n* Pregnancy\n* Any respiratory infection in last 4 weeks\n* PFT relative contraindications\n* History of major cardiovascular, pulmonary, renal, hepatic, autoimmune or neuromuscular disease including asthma, COPD, interstitial lung disease, heart failure, pulmonary arterial hypertension, or prior pulmonary embolism\n* Active malignancy undergoing treatment or history of malignancy involving the lung",true,"ALL","18 Years","99 Years",{"count":21,"type":22},40,"ESTIMATED","OBSERVATIONAL","Prospective cohort study to evaluate the utility of quantitative CT analysis to assess ventilation and perfusion defects in patients with Post-acute Sequelae of SARS-CoV-2 (PASC) and functional limitations",[26,27,28,29],"Post-Acute COVID-19","Post COVID-19 Condition","Post Viral Fatigue","Dyspnea",[31],"Ventilation Perfusion Mismatch","RECRUITING","2025-07-16",{"date":35,"type":36},"2025-07-20","ACTUAL",{"date":38,"type":36},"2023-06-05",{"date":40,"type":22},"2026-12-31",{"name":42,"class":43},"Tufts Medical Center","OTHER",""]