[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"premature-atrial-contraction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:premature-atrial-contraction":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":12,"acronym":13,"eligibilityCriteria":14,"healthyVolunteers":10,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100609895",false,"NCT07220525","Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation","DISCRETE AF","Inclusion Criteria:\n\n* Are age 21 years or older\n* Have a HGNS device implanted for obstructive sleep apnea and followed up at UCSF Health\n* Are willing to abstain from using the upper airway stimulation device for no more than two consecutive days as instructed over the 14-day trial period\n* Able and willing to provide written informed consent\n\nExclusion Criteria:\n\n* Currently pregnant or trying to get pregnant\n* Are currently taking class 1 or 3 anti-arrhythmic medications\n* Have a history of permanent AF or expected to have continuous AF throughout the study period\n* Have congenital heart disease\n* Ventricular pacing \\>40%\n* Are unable to read or sign to provide informed consent","ALL","21 Years",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22],"NA","Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode following a night of disrupted or poor-quality sleep. This prospective, randomized, case-crossover study aims to examine the acute effects of sleep disruption on clinically relevant cardiac ectopy pertinent to AF.",[25,26,27,28],"Obstructive Sleep Apnea","Premature Ventricular Contraction (PVC)","Atrial Fibrillation (AF)","Premature Atrial Contraction",[30,31,32,33,28,34],"Sleep Apnea","Hypoglossal Nerve Stimulation Device","Atrial Fibrillation","Upper Airway Stimulation","Premature Ventricular Contraction","RECRUITING","2026-01-21",{"date":38,"type":39},"2026-01-23","ACTUAL",{"date":41,"type":39},"2025-12-15",{"date":43,"type":19},"2027-06-01",{"name":45,"class":46},"University of California, San Francisco","OTHER",""]