[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"racism\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:racism":93},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,69],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100476505",false,"NCT05484804","Accountability for Care Through Undoing Racism & Equity for Moms","Reducing Racial Disparities in Maternal Care Through Data-Based Accountability and Doula Support","ACURE4Moms","Inclusion Criteria:\n\nPractices:\n\n* Have at least 180 Black patient deliver over 2 years\n* Be willing to be randomized\n* Be willing to adhere to the study protocol\n\nPatient survey participants:\n\n* Start prenatal care at one of the study clinics during study implementation\n* Self-identify as Black or African American\n* Able to give consent and complete surveys and interviews in English\n\nPractice staff member participants:\n\n* Employed as either a provider, nurse\u002Fmedical assistant, or office administrator at one of the clinics in this study\n\nDoula participants:\n\n* Provide doula care to patients at one the clinics in this study\n\nExclusion Criteria:\n\nPractices:\n\n* Already integrated with Community-Based Doulas\n* Already have an Early Warning System or Disparities Dashboard",true,"FEMALE","12 Years","99 Years",{"count":21,"type":22},60000,"ESTIMATED","INTERVENTIONAL",[25],"NA","This project-also known as \"Accountability for Care through Undoing Racism \\& Equity for Moms\" or ACURE4Moms-aims to reduce Black-White maternal health disparities using multi-level interventions designed to decrease bias in prenatal care, improve care coordination, and increase social support. ACURE4Moms is a pragmatic 4-arm cluster randomized controlled trial conducted with 39 prenatal practices across North Carolina. Practices have been randomly assigned to receive either: Arm 1 (Standard Care): North Carolina Medicaid Care management for high-risk pregnancies; Arm 2 (Data Accountability and Transparency): North Carolina Medicaid Care Management + Practice-level Data Accountability interventions; Arm 3 (Community-Based Doula Support): North Carolina Medicaid Care Management + Community-Based Doula support intervention for high-risk patients during pregnancy and postpartum; or Arm 4 (Data Accountability and Transparency + Community-Based Doula Support): North Carolina Medicaid Care Management + Both Arms 2 and 3 interventions. During each practice's 2-year intervention period, the practice will initiate prenatal care for \\~750-1,500 patients (up to 60,000 patients total), whose outcomes the investigators will follow and compare between arms until all these patients have reached 1-year post-delivery.",[28,29,30,31,32,33],"Pregnancy Related","Maternal Health","Maternal Mortality","Low Birthweight","Racism","Implicit Bias","RECRUITING","2026-04-13",{"date":37,"type":38},"2026-04-17","ACTUAL",{"date":40,"type":38},"2023-06-05",{"date":42,"type":22},"2027-08-31",{"name":44,"class":45},"University of North Carolina, Chapel Hill","OTHER",1,{"id":48,"slug":4,"hasResults":10,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":46},"100477633","NCT05499507","The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)","Inclusion Criteria:\n\n* age ≥18 years\n* baseline BMI ≥30 kg\u002Fm2 and\u002For diagnosis of HTN (≥130\u002F80 x 2)\n* gestational age \\\u003C24 weeks by last menstrual period\n* smartphone ownership\n* self-identification as Black or African American","18 Years",{"count":54,"type":22},432,[25],"The overarching goal of our proposal is to reduce disparities in perinatal cardiovascular disease risk factors among Black women utilizing a community-driven, social ecological framework.",[28,58,59,32],"Hypertension","Obesity","2025-12-04",{"date":62,"type":38},"2025-12-11",{"date":64,"type":38},"2023-01-24",{"date":66,"type":22},"2028-12-10",{"name":68,"class":45},"Temple University",{"id":70,"slug":4,"hasResults":10,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":10,"sex":17,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":4,"studyType":23,"phases":79,"briefSummary":80,"conditions":81,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":46},"100508616","NCT05902741","The Impact of a Race-Based Stress Reduction Intervention","The Impact of a Race-Based Stress Reduction Intervention on Well-Being, Inflammation, and DNA Methylation in African American Women at Risk for Cardiometabolic Disease","Inclusion Criteria:\n\n* Between the ages of 50 and 75\n* Female\n* Post-menopausal (without menstrual period for at least 12 consecutive months)\n* Self-identified AA or Black\n* Able to write, read, speak English\n* Must have at least 1 of any of the following:\n\n  * Waist circumference \\>88 cm\n  * Systolic BP\\>130 mmHg and\u002F or diastolic BP\\>88 mmHg or on antihypertensive medications\n  * Diagnosed and\u002For being treated for hypercholesterolemia\n  * History of Type 2 diabetes\n\nExclusion Criteria:\n\n* History of myocardial infarction or ischemic heart disease\u002Fangina, stent placement, coronary artery bypass, left ventricular hypertrophy, congestive heart failure, or ischemic stroke\n* Any major immune-related disease (e.g., rheumatoid arthritis. lupus)\n* Use of immune-altering medications, such as glucocorticoids\n* Periodontal disease, bleeding gums, dental work in past 72 hours\n* Current smoker or has smoked in past 3 months\n* Active cancer\n* Active infection\n* Substance abuse\n* Cognitive or psychiatric disorder that would affect ability to participate in classes (Brief Screen for Cognitive Impairment total score of 8 or higher)","50 Years","75 Years",{"count":78,"type":22},300,[25],"The goal of this clinical trial is to learn whether a stress reduction program called Resilience, Stress, and Ethnicity (RiSE) improves well-being, inflammation, and the epigenome in African American (AA) women who have risk factors for heart or metabolic disease.\n\nThe main question it aims to answer is whether an intervention that integrates cognitive-behavioral strategies focused on the impact that social stress, such as racism, has on the body, racial identity development, and empowerment.\n\nParticipants will placed in one of the two following groups:\n\n* The RiSE program will focus on teaching participants how to reduce their stress levels and will meet online weekly for approximately 2 hours each week for 8 consecutive weeks.\n* The Health Education program will include education on how to improve general health and will meet online weekly for approximately 2 hours each week for 8 consecutive weeks.\n\nParticipants will provide saliva to measure cytokines and DNA methylation (DNAm), complete questionnaires, and have blood pressure, heart rate, and weight measured at the following clinic visits:\n\n1. Prior to starting the intervention\n2. Mid-way through the intervention (Week 4)\n3. End of the intervention (Week 8)\n4. Six (6) months after the completion of the intervention",[32,82,83],"Stress","Inflammation","2025-09-02",{"date":86,"type":38},"2025-09-09",{"date":88,"type":38},"2023-10-18",{"date":90,"type":22},"2028-01-31",{"name":92,"class":45},"Loyola University",""]