[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rectal-fistulas\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rectal-fistulas":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":4,"hasResults":10,"nctId":11,"briefTitle":12,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":10,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100627748",false,"NCT07452666","FISTULA-RFA Trial: Radiofrequency Ablation for Perianal Fistula","FISTULA-RFA Trial (Fistula Inactivation by Segmental Thermal Uniform Lesion Ablation-Radiofrequency Ablation): A Prospective, Multicenter, Single-Arm Pilot Study in Patients With Perianal Fistula","FISTULA-RFA","Inclusion Criteria:\n\n* Adults aged 20 to 74 years\n* Able and willing to provide written informed consent after receiving explanation of the study purpose, procedures, potential benefits, and risks\n* Diagnosed with one or more of the following perianal fistula types:\n\n  1. High trans-sphincteric fistula\n  2. Low trans-sphincteric fistula with high risk of fecal incontinence (sphincter injury risk)\n  3. Fistula with seton placement (seton in situ or previously placed per protocol)\n  4. Crohn's disease-associated perianal fistula\n  5. Complex fistula, including cases with a history of perineal or gynecologic surgery and\u002For recurrent fistula\n\nExclusion Criteria:\n\n* Superficial fistula that is expected to be curable with simple fistulotomy with minimal risk of sphincter injury\n* Fistula related to malignancy\n* Any contraindication to RFA, including: History of stapled hemorrhoidopexy, Presence of endoscopic clips (or similar metallic clips) within the anal canal, Fecal diversion with stoma (diverting stoma in place), Pregnancy","ALL","20 Years","74 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this pilot clinical study is to learn whether radiofrequency ablation (RFA) can safely and effectively treat perianal fistulas in adults. It will also evaluate procedure-related safety and changes in symptoms over time. The main questions it aims to answer are:\n\n* How many participants achieve fistula closure by 6 months after RFA treatment?\n* How often do fistulas recur during follow-up?\n* What medical problems or adverse events occur after the RFA procedure (for example, pain, bleeding, infection, urinary retention, or changes in continence)?\n* How do patient-reported outcomes (such as pain and quality of life) change after treatment? This is a prospective, multicenter, single-arm pilot study. All participants will receive RFA treatment; there is no comparison (control) group.\n\nParticipants will:\n\n* Be screened and enrolled at one of the participating hospitals\n* Undergo a standardized RFA procedure for the perianal fistula\n* Attend follow-up visits with clinical assessments at regular time points up to 6 months (including key assessments around 3 and 6 months)\n* Report symptoms and any adverse events during the follow-up period",[27],"Rectal Fistulas",[29,30,31,32],"Rectal Fistula","RFA","Minimal Invasive Surgery","Radiofrequency Ablation","NOT_YET_RECRUITING","2026-03-01",{"date":36,"type":37},"2026-03-05","ACTUAL",{"date":39,"type":21},"2026-04-01",{"date":41,"type":21},"2027-08-30",{"name":43,"class":44},"Korea University Ansan Hospital","OTHER",""]